Updates in Magnetic Resonance Venous Imaging

2021 ◽  
Vol 38 (02) ◽  
pp. 202-208
Author(s):  
Pamela Lombardi ◽  
James C. Carr ◽  
Bradley D. Allen ◽  
Robert R. Edelman

AbstractFor years, magnetic resonance angiography (MRA) has been a leading imaging modality in the assessment of venous disease involving the pelvis and lower extremities. Current advancement in noncontrast MRA techniques enables imaging of a larger subset of patients previously excluded due to allergy or renal insufficiency, allowing for preintervention assessment and planning. In this article, the current status of MR venography, with a focus on current advancements, will be presented. Protocols and parameters for MR venographic imaging of the pelvis and lower extremities, including contrast and noncontrast enhanced techniques, will be reviewed based on a recent literature review of applied MR venographic techniques. Finally, several disease-specific entities, including pelvic congestion and compression syndromes, will be discussed with a focus on imaging parameters that may best characterize these disease processes and optimize anatomical planning prior to intervention.

2019 ◽  
Author(s):  
Yao-Kuang Huang ◽  
Yuan-Hsi Tseng ◽  
Chih-Hung Lin ◽  
Yuan-Hsiung Tsai ◽  
Yin-Chen Hsu ◽  
...  

Abstract Background: To explore the diagnostic performance of triggered angiography non-contrast-enhanced magnetic resonance imaging (TRANCE-MRI) for the evaluation of venous pathology of the lower extremity. Methods: This was a single-centre prospective cohort study of 25 patients with suspected venous disease in the lower extremities. Each patient received Doppler ultrasonography (for venous evaluation) before the scheduled TRANCE-MRI (for venous and arterial evaluations) on a 1.5T MR scanner (Philips Ingenia, Philips Healthcare, Best, the Netherlands), followed by lymphography and computed tomography angiography that were arranged according to the diagnostic indications. Results: The sensitivity, specificity and accuracy of TRANCE-MRI were 85.7%, 88/9% and 88%, respectively. The inter-rater agreement for deep vein thrombosis (DVT) of the thigh between the ultrasonography and TRANCE-MRI results was substantial agreement (Cohen's kappa κ, 0.72). In ultrasonography-negative cases, TRANCE-MRI detected four additional cases (16%, 4/25) of DVT; three cases (12%, 3/25) of venous compression caused by pelvic lymphadenopathy, hip prosthesis or knee joint effusion; one case (4%, 1/25) of vena cava anomaly; two cases (8%, 2/25) of occult peripheral artery disease (PAD); and one case (4%, 1/25) of an occluded bypass graft. Conclusion : TRANCE-MRI can be used as an alternative and objective tool for assessing lower extremity diseases, especially suspected venous pathology. Compared with ultrasonography, TRANCE-MRI plays a better role in assessing varicose veins of the lower extremities and deep veins of the pelvis and abdomen. However, false-positive results may occur in the left common iliac vein of elderly patients. Finally, occult PAD rarely occurs in patients with suspected lower extremity venous disease. Therefore, we recommend performing the TRANCE-MRV protocol instead of the full protocol (MRV+MRA) in the clinical setting in patients with venous scenarios.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Yao-Kuang Huang ◽  
Yuan-Hsi Tseng ◽  
Chih-Hung Lin ◽  
Yuan-Hsiung Tsai ◽  
Yin-Chen Hsu ◽  
...  

Abstract Background To explore the diagnostic performance of triggered angiography non-contrast-enhanced magnetic resonance imaging (TRANCE-MRI) for the evaluation of venous pathology of the lower extremity. Methods This was a single-centre prospective cohort study of 25 patients with suspected venous disease in the lower extremities. Each patient received Doppler ultrasonography (for venous evaluation) before the scheduled TRANCE-MRI (for venous and arterial evaluations) on a 1.5 T MR scanner (Philips Ingenia, Philips Healthcare, Best, the Netherlands), followed by lymphography and computed tomography angiography that were arranged according to the diagnostic indications. Results The sensitivity, specificity and accuracy of TRANCE-MRI were 85.7%, 88/9 and 88%, respectively. The inter-rater agreement for deep vein thrombosis (DVT) of the thigh between the ultrasonography and TRANCE-MRI results was substantial agreement (Cohen’s kappa κ, 0.72). In ultrasonography-negative cases, TRANCE-MRI detected four additional cases (16%, 4/25) of DVT; three cases (12%, 3/25) of venous compression caused by pelvic lymphadenopathy, hip prosthesis or knee joint effusion; one case (4%, 1/25) of vena cava anomaly; two cases (8%, 2/25) of occult peripheral artery disease (PAD); and one case (4%, 1/25) of an occluded bypass graft. Conclusion TRANCE-MRI can be used as an alternative and objective tool for assessing lower extremity diseases, especially suspected venous pathology. Compared with ultrasonography, TRANCE-MRI plays a better role in assessing varicose veins of the lower extremities and deep veins of the pelvis and abdomen. However, false-positive results may occur in the left common iliac vein of elderly patients. Finally, occult PAD rarely occurs in patients with suspected lower extremity venous disease. Therefore, we recommend performing the TRANCE-MRV protocol instead of the full protocol (MRV + MRA) in the clinical setting in patients with venous scenarios.


2019 ◽  
Author(s):  
Yao-Kuang Huang ◽  
Chih-Hung Lin ◽  
Yuan-Hsi Tseng ◽  
Yuan-Hsiung Tsai ◽  
Yin-Chen Hsu ◽  
...  

Abstract Background To explore the diagnostic performance of non-contrast-enhanced magnetic resonance imaging using triggered angiography non-contrast-enhanced sequence (TRANCE-MRI) in evaluation of venous pathology of the lower extremity. Methods This is a single-center prospective cohort study of 25 patients with suspected venous disease in their lower extremities. Each patient received a Doppler ultrasound exam before the scheduled TRANCE-MRI on a 1.5T MR scanner (Philips Ingenia, Philips Healthcare, Best, The Netherlands). The following lymphography and CTA were arranged according to the diagnostic indications. Results The venous scenarios of the 25 patient were divided as follows: 11 had deep venous thrombosis (DVT), seven had a static ulcer, three had symptomatic varicose veins (VV), two had recurrent VV after surgery, and two had lymphedema. TRANCE-MRI unexpectedly found that 4 patients (16%) had occult peripheral arterial occlusive disease. Of the 11 patients with scenario of DVT, 4 patients (36.4%) did not actually have DVT on TRANCE-MRI, and the symptoms were due to malignancy, external compression, and congenital anomalies. One patient (4%) with radiation-related lymphedema was falsely diagnosed as external iliac vein compression. Interrater agreement for DVT in the thigh between the ultrasonography and TRANCE-MRI was substantial agreement (Cohen's kappa κ, 0.72). The sensitivity, specificity and accuracy of TRANCE-MRI were 85.7%, 88/9% and 88%, respectively. Venous thrombi and collateral veins could be clearly outlined by TRANCE-MRI, including in middle femoral veins that might be difficult to detect by ultrasound. Conclusion TRANCE-MRI provided not only vascular image of the lower extremity but also information about the pelvis and abdomen. However, false positive results may occur in iliac vessels. TRANCE-MRI could outline venous thrombi and collateral veins from the abdomen to both calves, and thus, could be a powerful tool in the treatment of venous pathology in the lower extremities.


Author(s):  
Alan P. Koretsky ◽  
Afonso Costa e Silva ◽  
Yi-Jen Lin

Magnetic resonance imaging (MRI) has become established as an important imaging modality for the clinical management of disease. This is primarily due to the great tissue contrast inherent in magnetic resonance images of normal and diseased organs. Due to the wide availability of high field magnets and the ability to generate large and rapidly switched magnetic field gradients there is growing interest in applying high resolution MRI to obtain microscopic information. This symposium on MRI microscopy highlights new developments that are leading to increased resolution. The application of high resolution MRI to significant problems in developmental biology and cancer biology will illustrate the potential of these techniques.In combination with a growing interest in obtaining high resolution MRI there is also a growing interest in obtaining functional information from MRI. The great success of MRI in clinical applications is due to the inherent contrast obtained from different tissues leading to anatomical information.


2001 ◽  
Vol 45 (5) ◽  
pp. 465
Author(s):  
Myong Kwan Ko ◽  
Hee Lee ◽  
Sung Gwon Kang ◽  
Jeong Yeol Choi ◽  
Ju Nam Byun ◽  
...  

2021 ◽  
Vol 22 (12) ◽  
pp. 6504
Author(s):  
Peter Sang Uk Park ◽  
William Y. Raynor ◽  
Yusha Sun ◽  
Thomas J. Werner ◽  
Chamith S. Rajapakse ◽  
...  

In a healthy body, homeostatic actions of osteoclasts and osteoblasts maintain the integrity of the skeletal system. When cellular activities of osteoclasts and osteoblasts become abnormal, pathological bone conditions, such as osteoporosis, can occur. Traditional imaging modalities, such as radiographs, are insensitive to the early cellular changes that precede gross pathological findings, often leading to delayed disease diagnoses and suboptimal therapeutic strategies. 18F-sodium fluoride (18F-NaF)-positron emission tomography (PET) is an emerging imaging modality with the potential for early diagnosis and monitoring of bone diseases through the detection of subtle metabolic changes. Specifically, the dissociated 18F- is incorporated into hydroxyapatite, and its uptake reflects osteoblastic activity and bone perfusion, allowing for the quantification of bone turnover. While 18F-NaF-PET has traditionally been used to detect metastatic bone disease, recent literature corroborates the use of 18F-NaF-PET in benign osseous conditions as well. In this review, we discuss the cellular mechanisms of 18F-NaF-PET and examine recent findings on its clinical application in diverse metabolic, autoimmune, and osteogenic bone disorders.


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