Surgical Management of Parapharyngeal Tumors: Our Experience

Abstract Context Tumors of parapharyngeal space (PPS) are rare and histologically diverse. The management of these tumors requires diligent assessment and planning with due consideration of various anatomical and pathological aspects of the lesion. Aims This retrospective study aims to present our experiences in the clinical and pathological aspects of PPS tumors with a critical evaluation of management. Settings and Design Retrospective analytical study. Methods and Material The electronic medical records of 60 cases of PPS tumors, managed surgically from 2007 to 2017, were reviewed and analyzed using SPSS 22 software. The mean follow-up duration was 44 months. Results The mean age was 45 years with a male-to-female ratio of 1.7 (38:22). The majority of the tumors were benign (71.7%) and the most common presentation being upper neck mass or oropharyngeal mass. Histologically, neurogenic tumors were most common (43.3%) PPS tumors, followed by tumors of salivary gland origin. Magnetic resonance imaging was used as a diagnostic modality in 70% of cases, and computed tomography scan and positron emission tomography/CT were used in 26.7 and 3.3% of cases, respectively. In our study, the diagnostic accuracy of fine-needle aspiration cytology was 71% for benign and 47% for malignant lesions. The most common approach for surgery used was transcervical (72%). Conclusion The study reveals that cranial nerve palsy is the most common complication associated with PPS tumors. Completely resected, malignant tumors originating within PPS have a good prognosis, as compared with tumors extending or metastasized to PPS.

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ROLE OF FINE NEEDLE ASPIRATION CYTOLOGY (FNAC) IN BONE TUMORS AND TUMOR LIKE LESIONS

10.36106/ijsr/9622736 ◽

2021 ◽

pp. 69-70

Author(s):

Ragini Kumari ◽

Vikash M. Harinandan ◽

Kunal Shankar ◽

Ajit Kumar Chaudhary ◽

Debarshi Jana

Keyword(s):

Fine Needle Aspiration ◽

Bone Tumors ◽

Needle Aspiration ◽

Bone Lesions ◽

Diagnostic Modality ◽

Predictive Values ◽

Female Ratio ◽

Fine Needle ◽

Needle Aspiration Cytology

Background: FNAC is considered an important procedure in the diagnosis of bone tumors because of its high accuracy. In our study FNA was performed in patients to study the role of FNAC in the diagnosis of bone tumors and to evaluate its usefulness as a diagnostic modality. Methods: Fine needle aspiration was performed on 54 patients whose age ranged between 5 – 75 years with a male to female ratio 1.84 :1 presented with various bone lesions. The bone lesions included 42 (78%) primary lesions, 5 (9.3%) metastatic deposits and 7 (12. 7%) malignancy of related structures involving the bone. Results: 47 biopsy specimens were available for cytohistological correlation and cytological ndings of 45 cases correlated with histopathology. The overall diagnostic accuracy was 95.92%, with 100% sensitivity and specicity. The predictive values of positive as well as negative test were 100%. Conclusions:Thus FNAwas found to be a safe and an extremely useful, rapid method in the preliminary diagnosis of bone lesions.

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Fine-Needle Aspiration Biopsies of Ovarian Masses: A Reliable Technique

Acta Cytologica ◽

10.1159/000449362 ◽

2016 ◽

Vol 60 (5) ◽

pp. 465-474 ◽

Cited By ~ 2

Author(s):

Maral Mokhatri ◽

Golsa Shekarkhar ◽

Zahra Sarraf

Keyword(s):

Diagnostic Accuracy ◽

Fine Needle Aspiration ◽

Malignant Tumors ◽

Invasive Procedure ◽

Needle Aspiration ◽

Histological Diagnosis ◽

Diagnostic Modality ◽

Reliable Technique ◽

Fine Needle ◽

Ovarian Masses

Objective: In gynecology, fine-needle aspiration (FNA) has an overall accuracy of 94.5% in differentiation between benign and malignant tumors. The purpose of this study was to determine reliable cytological criteria for categorizing ovarian masses into benign and malignant categories, their subtypes, and also to evaluate FNA accuracy in the diagnosis of ovarian tumors in relation to histopathological findings. Study Design: A prospective study was performed on all patients with a preoperative diagnosis of ovarian tumor who were referred to our hospital between August 2013 and August 2015. During surgery, FNA was performed using an 18-gauge needle by a pathologist. Aspirated material was spread on clean glass slides and stained with Papanicolaou and Wright-Giemsa stains. The cytological findings and results were compared with the histological diagnosis. Results: Of the 81 cases in this study, there was a discrepancy between the cytological and histological diagnosis in 9 cases. The overall cytological diagnostic accuracy in our study was 88.9% with a sensitivity and specificity of 78.1 and 95.5%, respectively. Conclusion: FNA of an ovarian mass is a minimally invasive procedure with acceptable diagnostic accuracy, especially when differentiating between benign and malignant lesions, and can be considered as a useful diagnostic modality for choosing an appropriate management course.

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Cystic Echinococcosis of the Bone in Kazakhstan

Case Reports in Infectious Diseases ◽

10.1155/2018/9682508 ◽

2018 ◽

Vol 2018 ◽

pp. 1-4

Author(s):

Tommaso Manciulli ◽

Aigerim Mustapayeva ◽

Konrad Juszkiewicz ◽

Ekaterina Sokolenko ◽

Zhaksylik Maulenov ◽

...

Keyword(s):

Hospital Stay ◽

Cystic Echinococcosis ◽

Malignant Tumors ◽

Long Bones ◽

Female Ratio ◽

X Ray ◽

Male Female Ratio ◽

The Mean

Cystic echinococcosis (CE) is a parasitic zoonosis caused by E. granulosus primarily affecting the liver and lungs. CE of the bone is by far the most debilitating form of the disease and is very difficult to manage as it mimics malignant tumors. We reviewed bone CE cases admitted to a reference oncological hospital in Kazakhstan from January 2010 to February 2017. Among eight patients, the mean age was 33.5 years, and the male/female ratio was 1 : 3. Patients were examined by X-ray (8/8), CT (7/8), and MRI (3/8). CE was in the spine (2 cases), pelvis (3 cases), and long bones (humerus, tibia, and femur; one case for each). All patients were treated surgically. No perioperative albendazole was administered. No patient received albendazole afterwards. The mean hospital stay was 25 days. Interventions are urgently needed to assess the burden of CE in Kazakhstan and to inform clinicians of the existence of the disease.

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Paediatric neck masses – a diagnostic dilemma

The Journal of Laryngology & Otology ◽

10.1017/s0022215100137867 ◽

1997 ◽

Vol 111 (6) ◽

pp. 541-545 ◽

Cited By ~ 29

Author(s):

A. A. P. Connolly ◽

K. MacKenzie

Keyword(s):

Lymph Node ◽

Needle Aspiration ◽

Neck Mass ◽

Malignant Tumours ◽

Diagnostic Dilemma ◽

Neck Masses ◽

The Mean ◽

Needle Aspiration Cytology ◽

Sick Children ◽

Reactive Hyperplasia

AbstractThree hundred and sixty children who had a head and neck mass excised during 1987 to 1992 at the Royal Hospital for Sick Children, Glasgow were studied. There were 210 males and 150 females with a mean age of 60.7 months (0.5 to 198 months). Pilomatrixomata/sebaceous cysts (34 per cent), thyroglossal cysts (13 per cent), branchial remnants (nine per cent) and dermoids (nine per cent) accounted for almost twothirds of the 264 non-lymphadenomatous benign lesions excised. Ninety-three lymphadenopathy masses consisted of 60 with reactive hyperplasia, 21 with Mycobacterium infection and 12 lymphomas. There were three solid malignant tumours, two were rhabdomyosarcomata and one disseminated round cell tumour. The correlation between clinical diagnosis and histopathology of benign non-lymph node masses and solid tumours was 90 per cent and 100 per cent respectively, in benign lymph nodes, 66 per cent, but was poor in differentiating lymph node content. The mean time from presentation of a swelling to its excision was almost a year and the mean in-patient stay for excision of a mass was almost five days. The role of fine needle aspiration cytology (FNAC) in arriving at a diagnosis and reducing patient morbidity is discussed.

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A Case of Solitary Fibrous Tumor Presenting as Lower Neck Mass

Korean Society for Head and Neck Oncology ◽

10.21593/kjhno/2021.37.2.87 ◽

2021 ◽

Vol 37 (2) ◽

pp. 87-90

Author(s):

Sang Yen Geum ◽

Jeong Kyu Kim

Keyword(s):

Solitary Fibrous Tumor ◽

Malignant Tumors ◽

Neck Region ◽

Needle Aspiration ◽

Neck Mass ◽

Anatomic Site ◽

S 100 ◽

Hypoechoic Mass ◽

Fibrous Tumor ◽

Lower Neck

Solitary fibrous tumor (SFT) is rare mesenchymal tumor usually arising from pleura. SFT can be found at all anatomic site in our body but incidence of SFT is much lower in head and neck region especially at lower neck area. We found a case of SFT that presented as a lower neck mass in a 41-year old woman. Ultrasonography showed a 3×1cm sized hypoechoic mass in the intermuscular fat plane of left lower neck, and computed tomography showed a well circumscribed, low-density mass with contrast enhancement. Fine needle aspiration showed no malignant cells with abundant red blood cells, but it was not possible to completely rule out malignant tumors or nodules clinically. Surgery was performed to make a definitive diagnosis and histopathology showed tightly packed, round to fusiform cells with staghorn shaped vessels at microscopic examination. The tumor cell were positive for CD34 but negative for CD31 and S-100 protein.

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Diagnostic Value and Application of Infrared Thermography in the Analysis of Circumanal Gland Tumors

Frontiers in Veterinary Science ◽

10.3389/fvets.2021.692221 ◽

2021 ◽

Vol 8 ◽

Author(s):

Erika B. M. Zanuto ◽

Samanta R. Melo ◽

Eric V. Januário ◽

Gustavo A. A. L. Fernandes ◽

Julia M. Matera

Keyword(s):

Thermal Imaging ◽

Diagnostic Value ◽

Good Prognosis ◽

Skin Spot ◽

Diagnostic Modality ◽

The Third ◽

Tumor Center ◽

Common Skin ◽

The Mean ◽

Relapse Rates

In dogs, circumanal tumors are the third most common skin neoplasm. Circumanal gland adenomas (CAGAs) have a good prognosis. Contrastingly, circumanal gland adenocarcinomas (CAGAC) have high relapse rates and may be metastatic. This study aimed to investigate the utility of thermal imaging as an ancillary modality for the diagnosis of canine CAGA and CAGAC. We analyzed the following parameters: SpT, temperature measured at the tumor center; SpNT, temperature measured at a healthy sphincter skin spot distant from the tumor; TA, temperature measured at a tumor-encompassing ellipse-shaped area; and NTA, temperature measured at an ellipse-shaped area of the healthy sphincter skin distant from the tumor. In CAGAs, the mean SpT and SpNT temperature values differed by −1.45°C (p < 0.01) while the mean TA and NTA temperature values differed by −0.96°C (p < 0.05). In CAGACs, mean SpT and SpNT temperatures differed by −1.71°C (p < 0.01) while the mean TA and NTA temperatures differed by −1.69°C (p < 0.01). The mean SpT and TA temperature values measured in CAGAs and CAGACs differed by −0.10°C (p = 0.87) and 0.52°C (p = 0.38), respectively. Both tumors were colder than healthy sphincter skin. However, a substantial number of CAGACs were colder than CAGAs. Temperature differences ≥ 1°C between tumors and healthy sphincter skin increased the probability of CAGAC diagnosis by 17.45%. Thermal imaging allowed discrimination between healthy and tumoral tissues; therefore, it could be a good ancillary diagnostic modality.

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Clinical profile of amoebic liver abscess patients admitted in a tertiary care hospital

Bangladesh Medical Journal Khulna ◽

10.3329/bmjk.v48i1-2.27093 ◽

2016 ◽

Vol 48 (1-2) ◽

pp. 20-23 ◽

Cited By ~ 1

Author(s):

Bishnupada Paik ◽

Swapan Kumar Sarkar ◽

Poritosh Kumar Chowdhury ◽

Saad Ahmed

Keyword(s):

Clinical Features ◽

Liver Abscess ◽

Tertiary Care ◽

Needle Aspiration ◽

Clinical Profile ◽

Amoebic Liver Abscess ◽

Care Hospital ◽

College Hospital ◽

Female Ratio ◽

The Mean

Amoebic liver abscess is an important cause of space occupying lesions of the liver, especially in tropical and sub tropical regions. It is the most frequent complication of invasive amebiasis. It may be found in all age groups but relatively rare in children. The signs and symptoms vary according to the severity of illness. The present study was done to evaluate the clinical profile of patients with amoebic liver abscess for age, gender, clinical features, site of abscess, number of abscess, treatment modality by intravenous metronidazole along with percutaneous needle aspiration and prognosis. A prospective study of 86 admitted patients of amoebic liver abscess were included in this study which was carried out in the medicine department of Khulna Medical College Hospital over a period of 2 years from July 2010 to June 2012. Mean age of patients was 45 years. Male female ratio was 7:1. The mean duration of fever was 17.9 days and the mean duration of pain was 14.1 days. The duration of fever for more than 2 weeks was seen in 38 cases. Regarding clinical features, the major symptoms of fever, pain abdomen and dysentery were seen in 81, 78 and 10 cases respectively. The major signs as determined by clinical and radio imaging studies were hepatomegaly in 76, right lobe abscess in 60, left lobe abscess in 12, multiple abscesses in both lobes in 18, ascites in 5 and right sided pleural effusion in 12 cases respectively. All the cases underwent percutaneous needle aspiration. 5 cases died out of 86 patients.Bang Med J (Khulna) 2015; 48 : 20-23

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Clinical and Morphological Spectrum of Histoplasmosis on Cytology Along with the Review of Literature

Acta Cytologica ◽

10.1159/000509151 ◽

2020 ◽

Vol 64 (6) ◽

pp. 532-538

Author(s):

Gargi Kapatia ◽

Ashmita Saha ◽

Manish Rohilla ◽

Parikshaa Gupta ◽

Nalini Gupta ◽

...

Keyword(s):

Fine Needle Aspiration ◽

Giant Cells ◽

Needle Aspiration ◽

Review Of Literature ◽

Aspiration Cytology ◽

Female Ratio ◽

Fine Needle ◽

The Mean ◽

Needle Aspiration Cytology ◽

Male To Female

Objective: The aim of the study was to study the clinical and morphological spectrum of histoplasmosis diagnosed by fine needle aspiration cytology (FNAC). Study Design: A total of 17 patients diagnosed with histoplasmosis on FNAC were studied over a period of 5 years. The cytology smears were studied and analysed for the cytomorphological spectrum of histoplasmosis. Results: Among the 17 patients studied, the mean age was 51.3 years (range 6–84 years). Male-to-female ratio was 3.25:1 with 4 females and 13 males. The frequent sites of involvement were the lung (5), lymph node (4), adrenal gland (4), and skin (4). The most common cytological patterns were histiocytic collection, followed by granulomas and multinucleated giant cells. Necrosis was noted in only 4 cases. Conclusion: Fine needle aspiration is a highly accurate, rapid, and cheap technique for the diagnosis of histoplasmosis due to its distinct morphological features.

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Parapharyngeal space tumors: a serial case study

Journal of International Medical Research ◽

10.1177/0300060519862659 ◽

2019 ◽

Vol 47 (8) ◽

pp. 4004-4013

Author(s):

Kuang-Hsu Lien ◽

Chi-Kuang Young ◽

Shy-Chyi Chin ◽

Chun-Ta Liao ◽

Shiang-Fu Huang

Keyword(s):

Parapharyngeal Space ◽

Clinical Symptoms ◽

Malignant Tumors ◽

Neck Mass ◽

Surgical Approaches ◽

Common Symptom ◽

Neck Tumors ◽

The Mean

Objective Primary parapharyngeal space (PPS) tumors are one of the most challenging head and neck tumors to diagnose and treat. We analyzed our experience in patients with PPS tumors who were treated in our hospital over 13 years. Methods We retrospectively reviewed 16 patients with PPS tumors between 2006 and 2018. The study included clinical symptoms, histological types, surgical approaches, adjuvant therapies, postoperative complications, and prognosis. Results The mean age of the patients was 49.63 ± 17.03 years. A palpable neck mass (56.3%) was the most common symptom. In our series, 78.6% of the tumors were benign, and of these, schwannomas were the most common (6/14, 42.9%). Three surgical approaches were used in our patients, including transmandibular (57.1%), transcervical (21.4%) and transparotid (21.4%) approaches. Few complications were reported, including hoarseness and numbness. Adjuvant therapy was administered depending on pathological parameters of the tumors. No recurrence was observed during a mean follow-up of 60.6 months in patients with malignant tumors. Conclusions Radiological studies of PPS tumors are essential for diagnosis and surgical planning. Excision of PPS tumors using appropriate surgical approaches provides good outcomes.

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Giant Benign Mediastinal Masses Extending into the Pleural Cavity

The Surgery Journal ◽

10.1055/s-0036-1584519 ◽

2016 ◽

Vol 02 (02) ◽

pp. e46-e50

Author(s):

Güven Sunam ◽

Murat Öncel ◽

Sami Ceran ◽

Kemal Ödev ◽

Hüseyin Yıldıran

Keyword(s):

Pleural Cavity ◽

Correct Diagnosis ◽

Posterior Mediastinum ◽

Exertional Dyspnea ◽

Female Ratio ◽

Neurogenic Tumors ◽

Mediastinal Masses ◽

The Mean ◽

Magnetic Resonance Imaging Mri ◽

Male To Female

Introduction The aim of the study was to evaluate the results of surgery to remove huge mediastinal masses and their pathology. Surgical resection was chosen for accurate diagnosis and treatment of the huge mediastinal masses extending into the pleural cavity. Methods Records were reviewed for eight patients who had the diagnosis of huge benign mediastinal masses and who underwent operation; details of the patients and operations were recorded. Results Mean age was 34.5 (range 22 to 44) years, and male-to-female ratio was 2:6. Computed tomography and magnetic resonance imaging (MRI) were used to evaluate the location and extent of the abnormality and to characterize the tissue components of the mass. Most of the tumors were located in the posterior mediastinum. The most frequent presenting symptom was exertional dyspnea. The majority of cases underwent posterolateral thoracotomy, and complete resection was possible in seven patients. Partial resection could only be performed in one. The mean diameter of the resected masses was 15 × 10 cm. Histopathologic examination revealed 3 neurogenic tumors, 2 teratomas, 1 thymolipoma, and 1 ectopic thyroid, and 1 hemangioma. Minor complication was seen in two cases. Conclusion The presurgical thoracic MRI provided correct diagnosis along with radiologic characterization and topography. Surgery must be the preferred treatment in huge benign mediastinal masses.

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