scholarly journals Spin wave mediated unidirectional vortex core reversal by two orthogonal monopolar field pulses: The essential role of three-dimensional magnetization dynamics

2016 ◽  
Vol 119 (17) ◽  
pp. 173901 ◽  
Author(s):  
Matthias Noske ◽  
Hermann Stoll ◽  
Manfred Fähnle ◽  
Ajay Gangwar ◽  
Georg Woltersdorf ◽  
...  

Nanoscale ◽  
2018 ◽  
Vol 10 (21) ◽  
pp. 9981-9986 ◽  
Author(s):  
Sourav Sahoo ◽  
Sucheta Mondal ◽  
Gwilym Williams ◽  
Andrew May ◽  
Sam Ladak ◽  
...  

Time resolved measurement and numerical study of ultrafast spin dynamics in a 3D Co tetrapod structure revealed complex spin-wave modes.



Leonardo ◽  
2020 ◽  
Vol 53 (1) ◽  
pp. 63-69
Author(s):  
Jasmina Stevanov ◽  
Johannes M. Zanker

The dogmatic nature of Piet Mondrian’s neoplasticism manifesto initiated a discourse about translating aesthetic ideals from paintings to 3D structures. Mondrian rarely ventured into architectural design, and his unique interior design of “Salon de Madame B … à Dresden” was not executed. The authors discuss physical constraints and perceptual factors that conflict with neoplastic ideals. Using physical and virtual models of the salon, the authors demonstrate challenges with perspective projections and show how such distortions could be minimized in a cylinder. The paradoxical percept elicited by a “reverspective” Mondrian-like space further highlights the essential role of perceptual processes in reaching neoplastic standards of beauty.



2018 ◽  
Author(s):  
Stephanie A. Schalbetter ◽  
Geoffrey Fudenberg ◽  
Jonathan Baxter ◽  
Katherine S. Pollard ◽  
Matthew J. Neale

AbstractDuring meiotic prophase, chromosomes organise into a series of chromatin loops emanating from a proteinaceous axis, but the mechanisms of assembly remain unclear. Here we elucidate how this elaborate three-dimensional chromosome organisation is underpinned by genomic sequence in Saccharomyces cerevisiae. Entering meiosis, strong cohesin-dependent grid-like Hi-C interaction patterns emerge, reminiscent of mammalian interphase organisation, but with distinct regulation. Meiotic patterns agree with simulations of loop extrusion limited by barriers, yet are patterned by convergent transcription rather than binding of the mammalian interphase factor, CTCF, which is absent in S. cerevisiae—thereby both challenging and extending current paradigms of local chromosome organisation. While grid-like interactions emerge independently of meiotic chromosome synapsis, synapsis itself generates additional compaction that matures differentially according to telomere proximity and chromosome size. Collectively, our results elucidate fundamental principles of chromosome assembly and demonstrate the essential role of cohesin within this evolutionarily conserved process.





2012 ◽  
Vol 50 (01) ◽  
Author(s):  
N Lange ◽  
S Sieber ◽  
A Erhardt ◽  
G Sass ◽  
HJ Kreienkamp ◽  
...  


1995 ◽  
Vol 74 (05) ◽  
pp. 1323-1328 ◽  
Author(s):  
Dominique Lasne ◽  
José Donato ◽  
Hervé Falet ◽  
Francine Rendu

SummarySynthetic peptides (TRAP or Thrombin Receptor Activating Peptide) corresponding to at least the first five aminoacids of the new N-terminal tail generated after thrombin proteolysis of its receptor are effective to mimic thrombin. We have studied two different TRAPs (SFLLR, and SFLLRN) in their effectiveness to induce the different platelet responses in comparison with thrombin. Using Indo-1/AM- labelled platelets, the maximum rise in cytoplasmic ionized calcium was lower with TRAPs than with thrombin. At threshold concentrations allowing maximal aggregation (50 μM SFLLR, 5 μM SFLLRN and 1 nM thrombin) the TRAPs-induced release reaction was about the same level as with thrombin, except when external calcium was removed by addition of 1 mM EDTA. In these conditions, the dense granule release induced by TRAPs was reduced by over 60%, that of lysosome release by 75%, compared to only 15% of reduction in the presence of thrombin. Thus calcium influx was more important for TRAPs-induced release than for thrombin-induced release. At strong concentrations giving maximal aggregation and release in the absence of secondary mediators (by pretreatment with ADP scavengers plus aspirin), SFLLRN mobilized less calcium, with a fast return towards the basal level and induced smaller lysosome release than did thrombin. The results further demonstrate the essential role of external calcium in triggering sustained and full platelet responses, and emphasize the major difference between TRAP and thrombin in mobilizing [Ca2+]j. Thus, apart from the proteolysis of the seven transmembrane receptor, another thrombin binding site or thrombin receptor interaction is required to obtain full and complete responses.



1979 ◽  
Vol 42 (04) ◽  
pp. 1193-1206 ◽  
Author(s):  
Barbara Nunn

SummaryThe hypothesis that platelet ADP is responsible for collagen-induced aggregation has been re-examined. It was found that the concentration of ADP obtaining in human PRP at the onset of aggregation was not sufficient to account for that aggregation. Furthermore, the time-course of collagen-induced release in human PRP was the same as that in sheep PRP where ADP does not cause release. These findings are not consistent with claims that ADP alone perpetuates a collagen-initiated release-aggregation-release sequence. The effects of high doses of collagen, which released 4-5 μM ADP, were not inhibited by 500 pM adenosine, a concentration that greatly reduced the effect of 300 μM ADP. Collagen caused aggregation in ADP-refractory PRP and in platelet suspensions unresponsive to 1 mM ADP. Thus human platelets can aggregate in response to collagen under circumstances in which they cannot respond to ADP. Apyrase inhibited aggregation and ATP release in platelet suspensions but not in human PRP. Evidence is presented that the means currently used to examine the role of ADP in aggregation require investigation.



1996 ◽  
Vol 34 (1) ◽  
pp. 27
Author(s):  
Sue Yon Shim ◽  
Ki Joon Sung ◽  
Young Ju Kim ◽  
In Soo Hong ◽  
Myung Soon Kim ◽  
...  


2016 ◽  
Vol 2 (2) ◽  
pp. 40
Author(s):  
Miriam Aparicio

This study tests some hypotheses included in the psycho-social-communicational paradigm, which emphasizes the cognitive effects of the media and the role of the psychosocial subject as the recipient



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