scholarly journals The potency of java plum (Syzgium cumini) fruit extract as free radical scavenging in cigarette smoke

2019 ◽  
Author(s):  
A. A. S. A Sukmaningsih ◽  
Sofy Permana ◽  
D. J. D. H. Santjojo ◽  
Arinto Yudi P. Wardoyo ◽  
Sutiman B. Sumitro
Keyword(s):  
Free Radical ◽  
Cigarette Smoke ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Fruit Extract

Preliminary phytochemical analysis and evaluation of antioxidant, cytotoxic and inhibition of lipopolysaccaride - induced NOS (iNOS) expression in BALB/c mice liver by Ziziphus oenoplia Mill. fruit

2017 ◽  
Vol 14 (2) ◽  
Author(s):  
Ramaraj Thirugnanasampandan ◽  
Gunasekar Ramya ◽  
Gunasekaran Bhuvaneswari ◽  
Srinivasan Aravindh ◽  
Suresh Vaishnavi ◽  
...  
Keyword(s):  
Free Radical ◽  
Bioactive Compounds ◽  
Tamil Nadu ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Phytochemical Analysis ◽  
Fruit Extract ◽  
Ms Analysis ◽  
Wide Range ◽  
Mice Liver

AbstractBackground:Mill. is an ethnomedicinal plant and its fruit has been traditionally used by Puliar tribes of Anamalai Hills, Tamil Nadu, India to treat various ailments. Phytochemical analysis, antioxidant, cytotoxic and inducible nitric oxide synthase (Methods:To explore bioactive compounds present in the ripened fruits, high-performance thin-layer chromatography (HPTLC) and gas chromatography/mass spectrometry (GC–MS) analysis were done. Free radical scavenging, hepatoprotective, inhibition ofResults:Total flavonoid content of ZOFwas estimated as 69 µg/mg catechin equivalent. HPTLC densitogram confirmed the presence of quercetin and GC–MS analysis showed a total of 16 compounds of 87.66 % with quinic acid as a major compound which accounted for 22.29 %. Free radical-scavenging activity of ethanolic fruit extract was ranged from 160.12 to 650.23 µg/mL. An amount of 1.5 µg lipopolysaccharide (LPS)- induced severe inflammation in BALB/c mice liver, followed by treatment with ethanolic fruit extract of 100 µg concentration, exhibited significant hepatoprotection and reverse transcriptase polymerase (RT-PCR) analysis showed downregulation ofConclusions:Findings of the present study prove that ZOF is a rich source of bioactive compounds with a wide range of pharmacological activities. Hence, consumption of this wild edible fruit will be a cost-effective and easily available natural nutritional source for health protection.

Evaluation of free radical scavenging and antityrosinase activities of standardized longan fruit extract

2007 ◽  
Vol 45 (2) ◽  
pp. 328-336 ◽  
Author(s):  
Nuchanart Rangkadilok ◽  
Somkid Sitthimonchai ◽  
Luksamee Worasuttayangkurn ◽  
Chulabhorn Mahidol ◽  
Mathuros Ruchirawat ◽  
...  
Keyword(s):  
Free Radical ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Fruit Extract

Composition of Dithyrea wislizenii fruit extract and free-radical scavenging activity of its constituents

2012 ◽  
Vol 90 (8) ◽  
pp. 652-659 ◽  
Author(s):  
Sabine Montaut ◽  
Julie Grandbois ◽  
Laura S. Rossi ◽  
Sonia Kamal ◽  
James Khouri ◽  
...  
Keyword(s):  
Free Radical ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Positive Control ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activity ◽  
Scavenging Activity ◽  
Activity Assay ◽  
Fruit Extract ◽  
Brine Shrimp Lethality Assay

Glucolesquerellin (2), glucohesperin (3), quercetin 3-O-sophoroside (4), and quercetin 3-O-sophoroside-7-O-glucoside (5), isolated from the fruit of Dithyrea wislizenii , were quantified by HPLC. The fruit extract and flavonoids were not found to be toxic by using a brine shrimp lethality assay. The fruit extract and the flavonoids and glucosinolates were submitted to a free-radical scavenging activity assay with the diphenylpicrylhydrazyl radical (DPPH•). The concentration of quercetin (6) (a positive control for the flavonoids) able to scavenge 50% of DPPH• (SC50) was 32 ± 2 µmol/L (or 4 ± 1 µg/mL), which was about 27 times more potent than the crude extract. Compounds 4 and 5 had a SC50, the concentration of the compound required to scavenge 50% of the DPPH•, of 78 ± 1 µmol/L and 113 ± 10 µmol/L, respectively. The positive control for the glucosinolates, glucoraphasatin, (1) had a SC50 of 1768 ± 60 µmol/L. The glucosinolates 2 and 3 had a SC50 of 7819 ± 1968 and 970 ± 63 µmol/L, respectively.

scholarly journals Antioxidant and free radical scavenging potential of Citrullus colocynthis (L.) Schrad. methanolic fruit extract

2008 ◽  
Vol 58 (2) ◽  
Author(s):  
Sunil Kumar ◽  
Dinesh Kumar ◽  
Man Jusha ◽  
Kamal Saroha ◽  
Nidhan Singh ◽  
...  
Keyword(s):  
Free Radical ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Citrullus Colocynthis ◽  
Fruit Extract

scholarly journals Free Radical Scavenging and Analgesic Activities of Cucumis sativus L. Fruit Extract

2010 ◽  
Vol 2 (4) ◽  
pp. 365-368 ◽  
Author(s):  
D. Kumar ◽  
S. Kumar ◽  
J. Singh ◽  
Narender ◽  
Rashmi ◽  
...  
Keyword(s):  
Free Radical ◽  
Cucumis Sativus ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Fruit Extract ◽  
Cucumis Sativus L ◽  
Analgesic Activities

Determination of Free Radical Scavenging Potential in Cucumis melo (L). Fruit Extract

2021 ◽  
pp. 5084-5088
Author(s):  
Vidya R ◽  
Kalaivani K
Keyword(s):  
Free Radical ◽  
Cucumis Melo ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Ethanolic Extract ◽  
Ethanol Extract ◽  
Free Radical Scavenging ◽  
Scavenging Activity ◽  
Fruit Extract

The human body has an elaborate antioxidant defence system. Antioxidants are manufactured within the body and may even be extracted from the food like fruits, vegetables, seeds, nuts, meats and oil. Fresh fruits and vegetables are a rich source of antioxidant vitamins such as A, C and E, that prevent cellular damage associated with many diseases. This present investigation was designed to evaluate the radical scavenging activity of ethanolic extract of Cucumis melo fruit. The in vitro free radical scavenging effect of the Cucumis melo (L) fruit extract was assessed by using 1,1 – diphenyl 2-picryl hydrazyl radical (DPPH), ABTS (2, 2’-Azinobis (3-ethyl Benz Thiazoline-6-Sulfonic acid) hydroxyl radical, reducing power and nitric oxide scavenging assay. The scavenging activity of the fruit extract was tested at different concentrations. C.melo fruit extract showed concentration dependant free radical scavenging activity. Ethanol extract of Cucumis melo fruit (EECMF) exhibited maximum scavenging activity against DPPH (64.46%), ABTS (70.52%) hydroxyl radical (62.57%), and nitric oxide (61.18%) in comparison with standard antioxidants. The reducing power of ethanol extract of C.melo fruit was found to be 0.11 at 0.2mg/ml and increased to 0.49 at 1mg/ml. These results clearly indicate that ethanolic extract of C.melo fruit has great potential of free radical scavenging activity and it may be used as a bioactive source of natural antioxidants for pharmacology of functional foods.

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