An antimalarial constituent from alkaloid medang lendir (Litsea glutinosa (Lour.) C. B. Rob)

Objective: To evaluate the chemical composition, antibacterial and antioxidant properties of stem bark essential oil of Litsea glutinosa C. B. Rob.Methods: The essential oil isolated from stem bark of L. glutinosa and their chemical composition was analyzed by gas chromatography coupled with mass spectrometry detector. The in vitro antibacterial activity of the stem bark essential oil was investigated against eight human pathogenic bacterial clinical isolates using agar disc diffusion method and MIC value was determined by modified resazurin microtitre-plate assay. The antioxidant activity of essential oil was measured by 2, 2-diphenyl-1-picrylhydrazyl radical (DPPH), 2, 2-azinobis-3-ethylbenzothiazoline-6-sulphonate radical cation (ABTS) and β-carotene bleaching assay.Results: GC-MS analysis of stem bark essential oil resulted in the identification of 37 compounds, off which 9,12-octadecadienoic acid (62.57%), hexadecanoic acid (12.68%), stigmast-5-en-3-ol (6.87%) and vitamin E (2.51%) were the main constituents representing 84.63% of the oil. The determination of in vitro antibacterial activity of stem bark essential oil resulted in significant inhibition zone (15.00±0.57 mm) and MIC value (0.15±0.15×10-2 mg/ml) against the pathogenic bacteria Vibrio cholera followed by Pseudomonas aeruginosa and Salmonella typhi. The results of DPPH radical scavenging (IC50:4.540±0.06 µg/ml), ABTS (IC50:256.02±0.06 µg/ml) and β-carotene bleaching assay (%I: 78.51±0.42 %) showed significant in vitro antioxidant property.Conclusion: L. glutinosa stem bark essential oil showed potential antibacterial activity against the Vibrio cholera. The results of this investigation supported the ethnomedical claim of essential oil as a demulcent, antidiarrheal and antioxidant drug.

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Anti-hyperglycemic and anti-hyperlipidemia effects of the alkaloid-rich extract from barks of Litsea glutinosa in ob/ob mice

Scientific Reports ◽

10.1038/s41598-018-30823-w ◽

2018 ◽

Vol 8 (1) ◽

Cited By ~ 5

Author(s):

Xiaopo Zhang ◽

Yan Jin ◽

Younan Wu ◽

Caiyun Zhang ◽

Dejun Jin ◽

...

Keyword(s):

Litsea Glutinosa

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Litsea glutinosa (Indian Laurel).

10.1079/fc.31024.20210113940 ◽

2021 ◽

Author(s):

Manuel Angel Duenas-Lopez

Keyword(s):

Litsea Glutinosa

Abstract A datasheet on Litsea glutinosa covering, as an economically important tree, its taxonomy, importance, silviculture, distribution, biology and ecology, uses, products and pests.

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Introduction Pages

Notulae Scientia Biologicae ◽

10.15835/nsb10110272 ◽

2018 ◽

Vol 10 (1) ◽

pp. I-VI

Author(s):

Radu E. SESTRAS

Keyword(s):

Carbon Sequestration ◽

Reproductive Behavior ◽

Mass Production ◽

Life Science ◽

Banana Peel ◽

Wildlife Sanctuary ◽

Technical Aspects ◽

Litsea Glutinosa ◽

Radiation Treatments ◽

Senna Alata

Notulae Scientia Biologicae (http://www.notulaebiologicae.ro), Issue 1, Volume 10, 2018: The papers published in this issue (http://www.notulaebiologicae.ro/index.php/nsb/issue/current) represent interesting novelties in different topics of life science. Among the exciting researches, we invite you to find news about enhancing the resistance of watermelon; biodiversity within Mt. Hamiguitan Range Wildlife Sanctuary; bioactive compounds investigated in several species (Litsea glutinosa, Senna alata, etc.); new approaches for technical aspects for improving crops of interest (mass production of Spirulina, gamma radiation treatments on potato and sesame, testing banana peel as substrate); cytogenetic, forestry and carbon sequestration; reproductive behavior with significant embryological data. Notulae Scientia Biologicae journal has moved to online-only publication at the start of 2017. At the same time, we maintain our standard publication, as printed form, with 'classic' style - volume, issue, pagination.

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Determination of informant consensus factor of ethnomedicinal plants used in Kalenga forest, Bangladesh

Bangladesh Journal of Plant Taxonomy ◽

10.3329/bjpt.v21i1.19272 ◽

2014 ◽

Vol 21 (1) ◽

pp. 83-91 ◽

Cited By ~ 13

Author(s):

Mohammad Zashim Uddin ◽

Md. Abdul Hassan

Keyword(s):

Healthcare Management ◽

Forest Area ◽

New Drugs ◽

Average Value ◽

Informant Consensus ◽

Plant Taxon ◽

Litsea Glutinosa ◽

Ethnomedicinal Uses ◽

Herbal Formulations

The present article tried to document the ethnomedicinal uses of plants and determine the consensus factor among villagers of Kalenga forest area to evaluate the potential for new drugs of herbal origin. This study was conducted in 2010 using semi-structured questionnaire with villagers engaged in the forest management. The present study documented 35 plant species under 25 families for treatment of 11 categories of ailments using 52 medicinal formularies in Kalenga forest area. There was great agreement among the informants regarding ethnomedicinal uses of plants with Factor of Informants Consensus (FIC) value ranging from 0.50 to 0.95, with an average value of 0.73. The study revealed that most of the informants agreed in the use of Litsea glutinosa (Lour.) Roxb. to treat dysentery (FIC 0.95) that showed the highest fidelity level (95.23%). The results of the study also indicated that L. glutinosa might be used for the development of new, cheap, effective, and eco-friendly herbal formulations for healthcare management. Villagers views and our observations confirmed that L. glutinosa is a rare plant in the study area. Illegal and unsustainable collection of bark from this tree by the local crude drug traders considered as major causes of its depletion from nature.DOI: http://dx.doi.org/10.3329/bjpt.v21i1.19272Bangladesh J. Plant Taxon. 21(1): 83-91, 2014 (June)

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