scholarly journals Neuronal (type I) nitric oxide synthase regulates nuclear factor B activity and immunologic (type II) nitric oxide synthase expression

1997 ◽  
Vol 94 (6) ◽  
pp. 2676-2680 ◽  
Author(s):  
H. Togashi ◽  
M. Sasaki ◽  
E. Frohman ◽  
E. Taira ◽  
R. R. Ratan ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Type I ◽  
Nuclear Factor ◽  
Type Ii ◽  
Factor B ◽  
Oxide Synthase ◽  
Neuronal Type

scholarly journals Oestrogens inhibit interleukin 1 -mediated nitric oxide synthase expression in articular chondrocytes through nuclear factor- B impairment

2007 ◽  
Vol 66 (3) ◽  
pp. 345-350 ◽  
Author(s):  
P. Richette ◽  
M.-F. Dumontier ◽  
K. Tahiri ◽  
M. Widerak ◽  
A. Torre ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Articular Chondrocytes ◽  
Interleukin 1 ◽  
Nuclear Factor ◽  
Factor B ◽  
Oxide Synthase

ß-Catenin triggers nuclear factor ?B-dependent up-regulation of hepatocyte inducible nitric oxide synthase

2008 ◽  
Vol 40 (9) ◽  
pp. 1861-1871 ◽  
Author(s):  
Andrea Bandino ◽  
Alessandra Compagnone ◽  
Vittoria Bravoco ◽  
Carlo Cravanzola ◽  
Anna Lomartire ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Inducible Nitric Oxide Synthase ◽  
Nuclear Factor ◽  
Factor B ◽  
Oxide Synthase ◽  
Inducible Nitric Oxide

scholarly journals Distribution of Nitric Oxide Synthase in the Human Cerebral Blood Vessels and Brain Tissues

1994 ◽  
Vol 14 (6) ◽  
pp. 930-938 ◽  
Author(s):  
Hidekazu Tomimoto ◽  
Masaki Nishimura ◽  
Toshihiko Suenaga ◽  
Sinichi Nakamura ◽  
Ichiro Akiguchi ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Endothelial Cells ◽  
Cerebral Cortex ◽  
Nitric Oxide Synthase ◽  
Blood Vessels ◽  
Nadph Diaphorase ◽  
Type I ◽  
Type Ii ◽  
Cerebral Blood Vessels ◽  
Oxide Synthase

The distribution of nitric oxide synthase was investigated in human cerebral blood vessels and brain tissues. NADPH-diaphorase histochemistry, which is a marker for nitric oxide synthase in neurons and endothelial cells, revealed periadventitial nerve fibers in the arteries of the circle of Willis and their cortical branches, as well as the common carotid and subclavian arteries. The fibers were mostly nonvaricose in the periadventitial nerve trunk and were varicose within the adventitia. Patchy reaction products were distributed in the perinuclear region of each endothelial cell. Smooth muscle cells in the tunica media were weakly stained. Staining was particularly intense in regions with atherosclerotic changes, which consist of macrophage infiltration and proliferation of fibroblasts. In the neural parenchyma, two types of NADPH-diaphorase reactive neurons were differentiated. Type I neurons were intensely stained, medium-sized, and bipolar or multipolar. They were distributed in the cerebral cortex and white matter, mostly in the subcortical white matter. Type II neurons were lightly stained, small oval neurons with fine processes and were distributed in the cerebral cortex. Endothelial cells were intensely reactive for NADPH-diaphorase in the arteries, arterioles, and capillaries but weakly in veins. Immuno-histochemistry for neural nitric oxide synthase labeled perivascular nerves in the larger arteries and those in the neural parenchyma. Both type I and type II neurons were labeled. Nitric oxide synthase in endothelial cells and the nerve encircling blood vessels further suggests a dual control of cerebral circulation by nitric oxide in human brain.

Reduction of penile nitric oxide synthase in diabetic BB/WORdp (type I) and BBZ/WORdp (type II) rats with erectile dysfunction.

Endocrinology ◽  
1995 ◽  
Vol 136 (12) ◽  
pp. 5709-5717 ◽  
Author(s):  
D Vernet ◽  
L Cai ◽  
H Garban ◽  
M L Babbitt ◽  
F T Murray ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Erectile Dysfunction ◽  
Nitric Oxide Synthase ◽  
Type I ◽  
Type Ii ◽  
Oxide Synthase
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