“The people” in populist discourse

2017 ◽  
Vol 16 (4) ◽  
pp. 582-594 ◽  
Author(s):  
Paul Chilton

Abstract At the centre of populism is a problem of meaning. We could simply say it is a semiotic problem, but I would like to go further, and say that it’s a cognitive problem, one intrinsic to the human nervous system. It is a characteristic of our species that becomes highly active and significant in group action at certain social and historical conjunctures. The problem is the meaning of the word people, which on most accounts is centrally important for making out what the phenomenon called “populism” is about. It is unhelpful to say the word is meaningless or vague, because clearly something is going on in the minds of its users and their hearers. That something is not simply about denoting an entity; it is about activating a mental effect.

2020 ◽  
Vol 15 ◽  
Author(s):  
Smita P. Kakad ◽  
Sanjay J. Kshirsagar

Introduction: The infiltration of HIV into the brain alters the functions of the nervous system known as NeuroAIDS. It leads to neuronal defects clinically manifested by motor and cognitive dysfunctions. Materials/Methods: Current antiretroviral therapy can prevent viral replication but cannot cure the disease completely. HAART-Highly active antiretroviral therapy used for the treatment of HIV infection. Challenges in neuro-AIDS therapy are as shown in the graphical abstract. One of the challenges is latent viral reservoirs like the brain; which acts as a sanctuary site for viruses. Nearly ~50% of HIV patients show neuropathological signs. Nervous system related disorders including AIDS dementia, sensory neuropathy, and myelopathy have a 25% of prevalence in patients having access to a highly active combination antiretroviral therapy. Results/Conclusions: Brain is one of the viral sanctuary sites for HIV. The current need of neuro-AIDS therapy is to target the brain as a viral reservoir. Drugs should cross or bypass the blood-brain barrier to reach the brain with effective concentrations. Current research on novel drug delivery approaches may prove helpful to treat neuro-AIDS and related disorders effectively.


2021 ◽  
Vol 10 (10) ◽  
pp. 2149
Author(s):  
Ji Yeon Chung ◽  
Seung Jae Lee ◽  
Hyuck Jin Lee ◽  
Jeong Bin Bong ◽  
Chan-Hyuk Lee ◽  
...  

We evaluated the toxic effects of aconitine on the human nervous system and its associated factors, and the general clinical characteristics of patients who visited the emergency room due to aconitine intoxication between 2008 and 2017. We also analyzed the differences related to aconitine processing and administration methods (oral pill, boiled in water, and alcohol-soaked), and the clinical characteristics of consciousness deterioration and neurological symptoms. Of the 41 patients who visited the hospital due to aconitine intoxication, 23 (56.1%) were female, and most were older. Aconitine was mainly used for pain control (28 patients, 68.3%) and taken as oral pills (19 patients, 46%). The patients showed a single symptom or a combination of symptoms; neurological symptoms were the most common (21 patients). All patients who took aconitine after processing with alcohol showed neurological symptoms and a higher prevalence of consciousness deterioration. Neurological symptoms occurred most frequently in patients with aconitine intoxication. Although aconitine intoxication presents with various symptoms, its prognosis may vary with the processing method and prevalence of consciousness deterioration during the early stages. Therefore, the administration method and accompanying symptoms should be comprehensively investigated in patients who have taken aconitine to facilitate prompt and effective treatment and better prognoses.


1978 ◽  
Vol 177 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Ronald J. Chandross ◽  
Richard S. Bear ◽  
Royce L. Montgomery

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Muhammad Nabeel Anwar ◽  
Salman Hameed Khan

Human nervous system tries to minimize the effect of any external perturbing force by bringing modifications in the internal model. These modifications affect the subsequent motor commands generated by the nervous system. Adaptive compensation along with the appropriate modifications of internal model helps in reducing human movement errors. In the current study, we studied how motor imagery influences trial-to-trial learning in a robot-based adaptation task. Two groups of subjects performed reaching movements with or without motor imagery in a velocity-dependent force field. The results show that reaching movements performed with motor imagery have relatively a more focused generalization pattern and a higher learning rate in training direction.


1988 ◽  
Vol 267 (3) ◽  
pp. 398-408 ◽  
Author(s):  
David R. Hinton ◽  
Victor W. Henderson ◽  
Janet C. Blanks ◽  
Maria Rudnicka ◽  
Carol A. Miller

Brain ◽  
1974 ◽  
Vol 97 (1) ◽  
pp. 489-498 ◽  
Author(s):  
D. M. A. MANN ◽  
P. O. YATES

Human Cell ◽  
2006 ◽  
Vol 19 (2) ◽  
pp. 49-64 ◽  
Author(s):  
Noboru GOTO ◽  
Jun GOTO

2007 ◽  
Vol 18 (8) ◽  
pp. 575-576 ◽  
Author(s):  
Osamu Usami ◽  
Yugo Ashino ◽  
Yuichi Komaki ◽  
Masafumi Tomaki ◽  
Toshiya Irokawa ◽  
...  

Some of the HIV-1-infected patients who were given highly active anti-retroviral therapy (HAART) including efavirenz (EFV) presented adverse central nervous system (CNS) symptoms such as fatigue and insomnia. The incidence of adverse CNS symptoms is associated with hepatic cytochrome P450 isozymes (CYP2B6) polymorphisms. For example, CYP2B6 *6 (G516T and A785G) and *7 (G516T, A785G and C1459T) prolonged the EFV half-life despite discontinuation of EFV. CYP2B6 *2/*2 (C64T) is extremely rare and there have been no data describing the EFV plasma concentrations in C64T homozygous patients, who developed adverse CNS symptoms. C64T homozygous possibly has some catalytic defects.


Sign in / Sign up

Export Citation Format

Share Document