Resistance management for Bt maize and above-ground lepidopteran targets in the USA: from single gene to pyramided traits.

Author(s):  
F. N. Huang

2013 ◽  
Vol 106 (5) ◽  
pp. 1941-1951 ◽  
Author(s):  
Jennifer L. Petzold-Maxwell ◽  
Lance J. Meinke ◽  
Michael E. Gray ◽  
Ronald E. Estes ◽  
Aaron J. Gassmann


2007 ◽  
Vol 157 (suppl_1) ◽  
pp. S33-S37 ◽  
Author(s):  
Martin O Savage ◽  
Cecilia Camacho-Hübner ◽  
Alessia David ◽  
Louise A Metherell ◽  
Vivian Hwa ◽  
...  

Background: Idiopathic short stature (ISS) includes a range of conditions. Some are caused by defects in the GH–IGF-I axis. ISS is an approved indication for GH therapy in the USA and a similar approval in Europe may be imminent. Genetic analysis for single-gene defects has made enormous contributions to understanding the physiology of growth regulation. Can this type of investigation help in predicting growth responses to GH or IGF-I therapy? Methods: The rationale for choice of GH or IGF-I therapy in ISS is reviewed. Many ISS patients have low IGF-I, but most can generate IGF-I levels in response to short-term GH administration. Some GH resistance seems to be present. Mutation analysis in several cohorts of GHIS and ISS patients is reviewed. Results: Low IGF-I levels suggest either unrecognised GH deficiency or GH resistance. In classical GHIS patients, there was a positive relationship between IGFBP-3 levels and height SDS. No relationship exists between mutations and phenotype. There is a wide variability of phenotype in patients carrying identical mutations. Heterozygous GH receptor (GHR) mutations were present in <5% of ISS patients and their role in causing growth defects is questionable. Exceptions are dominant negative mutations that have been shown to disturb growth. Conclusions: Analysis for single-gene defects does not give sensitive predictions of phenotype and cannot predict responses to GH or IGF-I therapy. Endocrine abnormalities have closer correlations with phenotype and may thus be a better guide to therapeutic responsiveness.



2020 ◽  
Vol 76 (11) ◽  
pp. 3657-3666
Author(s):  
Ana M Camargo ◽  
María Arias‐Martín ◽  
Pedro Castañera ◽  
Gema P Farinós


Insects ◽  
2019 ◽  
Vol 10 (10) ◽  
pp. 343 ◽  
Author(s):  
Débora G. Montezano ◽  
Thomas E. Hunt ◽  
Alexandre Specht ◽  
Priscila M. C. Luz ◽  
Julie A. Peterson

Striacosta albicosta is a crop pest that causes economic damage in the United States and Canada. Only maize and dry beans are shown to be suitable hosts, since larval development is incomplete on other hosts. The objective of this study was to describe the developmental parameters of immature stages of S. albicosta feeding on dry beans, non-Bt, Cry1F, and Vip3A maize. For Vip3A, mortality was 100% after 24 h. Larvae feeding on non-Bt maize had the highest larval survival (70.6%) compared to the other hosts. Maize expressing Cry1F had higher survival (31.3%) than dry beans (26.0%). Larvae feeding on dry beans had a significantly faster total development time (74.8 days), compared to 92.5 days for non-Bt and 96.2 days for Cry1F. All larvae developed through seven instars. Pupae from larvae that had fed on non-Bt maize were significantly heavier than pupae from other hosts. An understanding of S. albicosta immature development on various host plants is needed to improve recommendations for effective scouting, treatment timing, and economic thresholds. Differential development can result in an extended adult emergence period, and possibly result in assortative mating between Bt susceptible and resistant populations, which violates the assumption of random mating necessary for current resistance management strategies for Bt maize. Therefore, understanding the impact of host plant and transgenic traits on aspects of pest biology will aid in developing effective integrated pest management and insect resistance management strategies for this pest.



2005 ◽  
Vol 129 (6) ◽  
pp. 281-292 ◽  
Author(s):  
J. A. Qureshi ◽  
L. L. Buschman ◽  
J. E. Throne ◽  
S. B. Ramaswamy


2010 ◽  
Vol 11 (1) ◽  
pp. 17 ◽  
Author(s):  
Odile Carisse ◽  
Tristan Jobin

Dodine was introduced in the USA and Canada in the early 1960s for the control of apple scab. Following control failure, growers stopped using dodine in the mid-1970s. Despite the curtailment of dodine use more than 30 years ago, persistent resistance to the fungicide was suspected in V. inaequalis populations. The dodine sensitivity was determined for two populations that were not exposed to dodine for at least 30 years – a wild type population (25 monoconidial isolates) and a population constructed with isolates collected in orchards managed for apple scab (156 isolates). The sensitivity to dodine was determined by monitoring growth of these isolates on agar Petri dishes amended with 0, 0.01, 0.1, 1.0, or 10.0 μg/ml of dodine. Sensitivity to fungicide was evaluated based on ED50 values. Both populations showed a lognormal distribution of ED50 values. The ED50 means were 0.525 μg/ml and 1.735 μg/ml for the wild type and managed orchards populations, respectively. In managed orchard, 31.4% of the isolates were resistant to dodine (ED50 > 1.0 μg/ml). Cross-resistance with myclobutanil and with kresoxim-methyl was tested and found not to be significant. The results of this study suggest that resistance to dodine is still present in the populations of V. inaequalis from Quebec and that reintroduction of dodine should only be done along with an appropriate resistance management strategy. Accepted for publication 27 April 2010. Published 14 June 2010.





2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Renato J. Horikoshi ◽  
Daniel Bernardi ◽  
Oderlei Bernardi ◽  
José B. Malaquias ◽  
Daniela M. Okuma ◽  
...  


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