scholarly journals The polyunsaturated fatty acid status of the twin foetal lamb and the effect of maternal nutrient intake

1982 ◽  
Vol 47 (1) ◽  
pp. 101-104
Author(s):  
E. Payne ◽  
P. V. Rattray
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Nutrient Intake ◽  
Fatty Acid Status ◽  
Acid Ratio ◽  
Acid Deficiency ◽  
Acid Status ◽  
Fatty Acid Deficiency ◽  
Foetal Lamb

1. Restriction of food to ewes bearing twin lambs showed a trend to decrease the level of ω6 fatty acids in muscle phospholipids of the foetus though this was not significant statistically (P < 0·05).2. There was a significant increase in the fatty acid ratio, 20:3ω9:20:4ω6 in the twin lambs as compared with single lambs.3. There were no symptoms of polyunsaturated fatty acid deficiency.

scholarly journals Membrane Omega-3 Fatty Acid Deficiency as a Preventable Risk Factor for Comorbid Coronary Heart Disease in Major Depressive Disorder

2009 ◽  
Vol 2009 ◽  
pp. 1-13 ◽  
Author(s):  
Robert K. McNamara
Keyword(s):  
Coronary Heart Disease ◽  
Risk Factor ◽  
Heart Disease ◽  
Fatty Acid ◽  
Omega 3 ◽  
Fatty Acid Status ◽  
Preventable Risk Factor ◽  
Acid Deficiency ◽  
Acid Status ◽  
Fatty Acid Deficiency

Major depression disorder (MDD) significantly increases the risk for coronary heart disease (CHD) which is a leading cause of mortality in patients with MDD. Moreover, depression is frequently observed in a subset of patients following acute coronary syndrome (ACS) and increases risk for mortality. Here evidence implicating omega-3 (n-3) fatty acid deficiency in the pathoaetiology of CHD and MDD is reviewed, and the hypothesis that n-3 fatty acid deficiency is a preventable risk factor for CHD comorbidity in MDD patients is evaluated. This hypothesis is supported by cross-national and cross-sectional epidemiological surveys finding an inverse correlation between n-3 fatty acid status and prevalence rates of both CHD and MDD, prospective studies finding that lower dietary or membrane EPA+DHA levels increase risk for both MDD and CHD, case-control studies finding that the n-3 fatty acid status of MDD patients places them at high risk for emergent CHD morbidity and mortality, meta-analyses of controlled n-3 fatty acid intervention studies finding significant advantage over placebo for reducing depression symptom severity in MDD patients, and for secondary prevention of cardiac events in CHD patients, findings that n-3 fatty acid status is inversely correlated with other documented CHD risk factors, and patients diagnosed with MDD after ACS exhibit significantly lower n-3 fatty acid status compared with nondepressed ACS patients. This body of evidence provides strong support for future studies to evaluate the effects of increasing dietary n-3 fatty acid status on CHD comorbidity and mortality in MDD patients.

Causal Link between n-3 Polyunsaturated Fatty Acid Deficiency and Motivation Deficits

2019 ◽  
Author(s):  
Fabien Ducrocq ◽  
Roman Walle ◽  
Andrea Contini ◽  
Asma Oummadi ◽  
Baptiste Caraballo ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Causal Link ◽  
Acid Deficiency ◽  
Fatty Acid Deficiency
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