Autoantibodies against inner ear proteins in patients with delayed endolymphatic hydrops and unilateral juvenile deafness

2006 ◽  
Vol 126 (2) ◽  
pp. 117-121 ◽  
Author(s):  
Mikio Suzuki ◽  
Masakazu Hanamitsu ◽  
Tsuyoshi Kitanishi ◽  
Hideaki Kohzaki ◽  
Hiroya Kitano
Keyword(s):  
Inner Ear ◽  
Endolymphatic Hydrops ◽  
Delayed Endolymphatic Hydrops

scholarly journals Menière's Disease and Disorders of the Carbohydrate Metabolism Involving the Inner Ear

2019 ◽  
Vol 23 (02) ◽  
pp. 218-220
Author(s):  
Pedro L. Mangabeira Albernaz
Keyword(s):  
Inner Ear ◽  
Carbohydrate Metabolism ◽  
Endolymphatic Hydrops ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Delayed Endolymphatic Hydrops ◽  
Ménière's Disease

Introduction Menière’s disease was described in 1861, but there are still uncertainties regarding its pathophysiology and treatment. Endolymphatic hydrops is recognized as a fundamental pathological characteristic of the disease, as a result of an inadequate absorption of the endolymph. A milder type of endolymphatic hydrops results from an altered chemical composition of the endolymph, due to disorders of the carbohydrate metabolism. Objective To describe the association of both types of hydrops in patients with Menière disease. Methods This was a retrospective study of 98 patients with Menière’s disease, 62 of whom also presented disorders of the carbohydrate metabolism, and 5 patients with delayed endolymphatic hydrops, 2 of whom also presented disorders of the carbohydrate metabolism. Results The follow-up of these patients showed that the correction of the metabolic disorders may help in the clinical treatment of Menière’s disease and of delayed endolymphatic hydrops, but this does not happen in the more severe types of the diseases. Conclusion Patients with Menière’s disease may present simultaneous disorders of the carbohydrate metabolism, affecting the inner ear. The correction of these disorders helps the clinical treatment but does not preclude the progression of the more severe cases of Menière disease.

Diagnostic value of three-dimensional magnetic resonance imaging of inner ear after intratympanic gadolinium injection, and clinical application of magnetic resonance imaging scoring system in patients with delayed endolymphatic hydrops

2013 ◽  
Vol 128 (1) ◽  
pp. 53-59 ◽  
Author(s):  
X Gu ◽  
Z-M Fang ◽  
Y Liu ◽  
S-L Lin ◽  
B Han ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Inner Ear ◽  
Endolymphatic Hydrops ◽  
Three Dimensional ◽  
Resonance Imaging ◽  
Positive Identification ◽  
Delayed Endolymphatic Hydrops ◽  
Intratympanic Injection ◽  
Perilymphatic Space

AbstractObjective:Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging of the inner ear after intratympanic injection of gadolinium, together with magnetic resonance imaging scoring of the perilymphatic space, were used to investigate the positive identification rate of hydrops and determine the technique's diagnostic value for delayed endolymphatic hydrops.Methods:Twenty-five patients with delayed endolymphatic hydrops underwent pure tone audiometry, bithermal caloric testing, vestibular-evoked myogenic potential testing and three-dimensional magnetic resonance imaging of the inner ear after bilateral intratympanic injection of gadolinium. The perilymphatic space of the scanned images was analysed to investigate the positive identification rate of endolymphatic hydrops.Results:According to the magnetic resonance imaging scoring of the perilymphatic space and the diagnostic standard, 84 per cent of the patients examined had endolymphatic hydrops. In comparison, the positive identification rates for vestibular-evoked myogenic potential and bithermal caloric testing were 52 per cent and 72 per cent respectively.Conclusion:Three-dimensional magnetic resonance imaging after intratympanic injection of gadolinium is valuable in the diagnosis of delayed endolymphatic hydrops and its classification. The perilymphatic space scoring system improved the diagnostic accuracy of magnetic resonance imaging.

Primary Intravestibular Lipoma

1989 ◽  
Vol 98 (5) ◽  
pp. 393-395 ◽  
Author(s):  
Tsun-Sheng Huang
Keyword(s):  
Inner Ear ◽  
Endolymphatic Hydrops ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Delayed Endolymphatic Hydrops ◽  
Ménière's Disease ◽  
Unusual Symptoms

An intravestibular lipoma was discovered during destructive surgery for disabling vertigo in a case diagnosed as delayed endolymphatic hydrops. The author recommends that in cases that resemble Meniere's disease but have unusual symptoms, the existence of other lesions within the inner ear should be suspected.

Clinical features and long-term outcome of ipsilateral delayed endolymphatic hydrops

2019 ◽  
Vol 69 (3) ◽  
Author(s):  
Andrea Albera ◽  
Claudia Cassandro ◽  
Carmine F. Gervasio ◽  
Sergio Lucisano ◽  
Marco Boldreghini ◽  
...  
Keyword(s):  
Clinical Features ◽  
Endolymphatic Hydrops ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Delayed Endolymphatic Hydrops

Evidence for bilateral endolymphatic hydrops in ipsilateral delayed endolymphatic hydrops: preliminary results from examination of five cases

2013 ◽  
Vol 134 (3) ◽  
pp. 221-226 ◽  
Author(s):  
Hiroshi Nonoyama ◽  
Tohru Tanigawa ◽  
Tsuneo Tamaki ◽  
Hirokazu Tanaka ◽  
Osamu Yamamuro ◽  
...  
Keyword(s):  
Endolymphatic Hydrops ◽  
Preliminary Results ◽  
Delayed Endolymphatic Hydrops

scholarly journals Gentamicin delivery to the inner ear: Does endolymphatic hydrops matter?

PLoS ONE ◽  
2018 ◽  
Vol 13 (11) ◽  
pp. e0207467 ◽  
Author(s):  
Pedro Marques ◽  
Maoli Duan ◽  
Nicolas Perez-Fernandez ◽  
Jorge Spratley
Keyword(s):  
Inner Ear ◽  
Endolymphatic Hydrops

scholarly journals Bridging the gap between chronic cerebrospinal venous insufficiency and Ménière disease

2016 ◽  
Vol 5 (2) ◽  
Author(s):  
Dario C. Alpini ◽  
Pietro M. Bavera ◽  
Federica Di Berardino ◽  
Stefania Barozzi ◽  
Piero Cecconi ◽  
...  
Keyword(s):  
Inner Ear ◽  
Major Part ◽  
Venous Insufficiency ◽  
Endolymphatic Hydrops ◽  
Meniere Disease ◽  
Number Of Patients ◽  
Hydraulic Mechanism ◽  
Collateral Pathways ◽  
Menière Disease ◽  
Global Brain

Ménière disease (MD) is a chronic illness of the inner ear that affects a substantial number of patients every year worldwide. Because of a dearth of well-controlled studies, the medical and surgical management of MD remains quite empirical. The main reason is that it is very difficult to investigate patients affected with Certain MD due to the post-mortem criterion necessary for this diagnostic grade. Although Endolymphatic Hydrops (EH) is the worldwide accepted mechanism of MD, the causes that induce it are still not clear. In fact MD has been correlated mostly to a wide and different disturbances ranging from trauma to sleep disorders. It is nowadays sufficiently demonstrated that Chronic Cerebro Spinal Venous Insufficiency (CCSVI) is very frequent in MD. Even if CCSVI may potentially induce EH through a pure hydraulic mechanism CCSVI, per se does not explain how the various disorders correlated with MD may interact with CCSVI and provoke EH. The aim of this review is an attempt to approach MD into the context of the more recent findings about the global brain waste clearance system, to which inner ear is anatomically and functionally connected, in order to build a reasonable model of MD pathogenesis. The major part of the diseases correlated to MD may act on the inner ear disturbing the Glymphatic (GS) and/or Brain Lymphatic System (BLS) activity. The venous system interplays with GS and BLS. In this model CCSVI is considered more than a direct cause of MD rather the anatomical predisposition to develop the disease. In this model EH, and then MD, is the consequence of a failure of the compensation of the congenital venous abnormalities, anatomical compensation as collateral pathways and/or functional compensation as GS and BLS. In this model the major part of the disturbances correlated to MD and the various treatment proposed find their appropriate placement.

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