The Long-term Effect of Bilateral Inferior Colliculus Ablation on Auditory Brainstem Response in Awake Cats

1999 ◽  
Vol 119 (2) ◽  
pp. 128-131 ◽  
Author(s):  
Kimitaka Kaga, Katsushi Yamada, Tos
Keyword(s):  
Inferior Colliculus ◽  
Auditory Brainstem Response ◽  
Auditory Brainstem ◽  
Term Effect ◽  
Long Term Effect ◽  
Brainstem Response ◽  
Awake Cats

Diffusion Tensor Imaging of Auditory Pathway in Patients With Crigler-Najjar Syndrome Type I: Correlation With Auditory Brainstem Response

2021 ◽  
pp. 088307382110258
Author(s):  
Ahmed Abdel Khalek Abdel Razek ◽  
Mohamed Ezz El Regal ◽  
Mortada El-Shabrawi ◽  
Mohamed Moustafa Abdeltawwab ◽  
Ahmed Megahed ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Inferior Colliculus ◽  
Cochlear Nucleus ◽  
Auditory Brainstem Response ◽  
Diffusion Tensor ◽  
Auditory Brainstem ◽  
Type I ◽  
Syndrome Type ◽  
Brainstem Response ◽  
Olivary Nucleus

Aim: To evaluate the role of diffusion tensor imaging of the auditory pathway in patients with Crigler Najjar syndrome type I and its relation to auditory brainstem response. Methods: Prospective study was done including 12 patients with Crigler Najjar syndrome type I and 10 age- and sex-matched controls that underwent diffusion tensor imaging of brain. Mean diffusivity and fractional anisotropy at 4 regions of the brain and brainstem on each side were measured and correlated with the results of auditory brainstem response for patients. Results: There was significantly higher mean diffusivity of cochlear nucleus, superior olivary nucleus, inferior colliculus, and auditory cortex of patients versus controls on both sides for all regions ( P = .001). The fractional anisotropy of cochlear nucleus, superior olivary nucleus, inferior colliculus, and auditory cortex of patients versus controls was significantly lower, with P values of, respectively, .001, .001, .003, and .001 on the right side and .001, .001, .003, and .001 on left side, respectively. Also, a negative correlation was found between the maximum bilirubin level and fractional anisotropy of the left superior olivary nucleus and inferior colliculus of both sides. A positive correlation was found between the mean diffusivity and auditory brainstem response wave latency of the right inferior colliculus and left cochlear nucleus. The fractional anisotropy and auditory brainstem response wave latency of the right superior olivary nucleus, left cochlear nucleus, and inferior colliculus of both sides were negatively correlated. Conclusion: Diffusion tensor imaging can detect microstructural changes in the auditory pathway in Crigler Najjar syndrome type I that can be correlated with auditory brainstem response.

Long-term course of Landau-Kleffner syndrome:

1999 ◽  
Vol 16 (1) ◽  
Author(s):  
Carla G. Matas ◽  
Renata A. Leite ◽  
Letícia L. Mansur ◽  
Laura M.F.F. Guilhoto ◽  
Maria Luiza G. Manreza
Keyword(s):  
Auditory Brainstem Response ◽  
Epileptic Seizures ◽  
Auditory Brainstem ◽  
Cognitive Domain ◽  
Speech Acquisition ◽  
Middle Latency Response ◽  
Brainstem Response ◽  
Latency Response ◽  
Middle Latency

Introduction. Landau-Kleffner Syndrome is characterized by normal speech acquisition followed by epileptic seizures, receptive and expressive language deterioration coupled with agnosia for non-verbal sounds, having variable long-term evolution. Case Report. It is described neurophysiologic and acoustic findings in a patient with Landau-Kleffner Syndrome, and correlate these with the results of a language evaluation carriedout 7 years after the acute phase. It is performed Electroencephalography, Immitance Measurements, Basic Audiometry, Auditory Brainstem Response, Middle Latency Response, and P300. Language was evaluated by Boston Diagnostic Aphasia Examination. Electroencephalography was normal and audiologic evaluation revealed normal Immitance Measurements, Basic Audiometry and Auditory Brainstem Response values. Anelectrode effect was present in the left hemisphere in Middle Latency Response, and bilateral P300 latencies delayed on the right. Language evaluation showed severe receptive and expressive impairment, severe phonemic substitutions, which had an impact on social and academic levels. There were contextual and gestual non-verbal compensations, evidencing intellectual and cognitive domain preservation. Conclusion. This case illustrates the specific cerebral areas that can be damaged in patients with Landau-Kleffner Syndrome and which are demonstrable by clinical evaluation and proper neurophysiology studies, showing the importance of neurological, audiological, electrophysiological and language exams in a longitudinal follow up.

scholarly journals Ipsilateral and Contralateral Auditory Brainstem Response Reorganization in Hemispherectomized Patients

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Ning Yao ◽  
Hui Qiao ◽  
Ping Li ◽  
Yang Liu ◽  
Liang Wu ◽  
...  
Keyword(s):  
Auditory Brainstem Response ◽  
Auditory Pathway ◽  
Auditory Brainstem ◽  
Subcortical Structures ◽  
Auditory Pathways ◽  
Control Subjects ◽  
Monaural Stimulation ◽  
Brainstem Response ◽  
Magnetic Resonance Imaging Mri

Background. Cortical hemispherectomy leads to degeneration of ipsilateral subcortical structures, which can be observed long term after the operation. Therefore, reorganization of the brainstem auditory pathway might occur. The aim of this study was to assess reorganization of brainstem auditory pathways by measuring the auditory brainstem response (ABR) in long-term hemispherectomized patients.Methods. We performed bilateral monaural stimulation and measured bilateral ABR in 8 patients~20 years after hemispherectomy and 10 control subjects. Magnetic resonance imaging (MRI) was performed in patients to assess structural degeneration.Results. All patients showed degenerated ipsilateral brainstem structures by MRI but no significant differences in bilateral recording ABR wave latencies. However, nonsurgical-side stimulation elicited significantly longer wave V latencies compared to surgical-side stimulation. Differences in bilateral ABR were observed between hemispherectomized patients and control subjects. Waves III and V latencies elicited by nonsurgical-side stimulation were significantly longer than those in control subjects; surgical-side stimulation showed no significant differences.Conclusions. (1) Differences in ABR latency elicited by unilateral stimulation are predominantly due to bilateral brainstem auditory pathway activity rather than to changes in brainstem volume; (2) ABR Waves III and V originate predominantly in the contralateral brainstem; and (3) subcortical auditory pathways appear to reorganize after long term hemispherectomy.

Sign in / Sign up

Export Citation Format

Share Document