Protective Role of PERK-eIF2α-ATF4 Pathway in Chronic Renal Failure Induced Injury of Rat Hippocampal Neurons

Author(s):  
Qi Chen ◽  
Jingjing Min ◽  
Ming Zhu ◽  
Zhanqin Shi ◽  
Pingping Chen ◽  
...  
2006 ◽  
Vol 58 (11) ◽  
pp. 1515-1525 ◽  
Author(s):  
Sumiyo Sasaki ◽  
Takako Yokozawa ◽  
Eun Ju Cho ◽  
Shigeru Oowada ◽  
Mujo Kim

1985 ◽  
Vol 75 (3) ◽  
pp. 1037-1044 ◽  
Author(s):  
M Akmal ◽  
S G Massry ◽  
D A Goldstein ◽  
P Fanti ◽  
A Weisz ◽  
...  

1995 ◽  
Vol 15 (2) ◽  
pp. 129-136 ◽  
Author(s):  
Hiroaki Suzuki ◽  
Liliana Schaefer ◽  
Hong Ling ◽  
Roland M. Schaefer ◽  
Jobst Dämmrich ◽  
...  

2020 ◽  
pp. 81-82
Author(s):  
Ramesh Chandra Thanna ◽  
B K Agarwal ◽  
Rakesh Romday ◽  
Neha Sharma

Introduction: Cardiovascular diseases (CVD) are known as important reasons of the increased morbidity and mortality observed in patients with chronic renal failure (CRF). The association of serum Interlukin-6 , homocysteine as well as other cardiovascular risk factors in relation to existence and cause of CVD were investigated. Method: In this study 200 CRF patients were recruited and further stratified into group with Male and Female as case groups. Those without renal failure were assigned as control group (n=200). Results: The patients with CRF showed a significant increase in plasma levels of Cpk-MB homocysteine and C-reactive protein (CRP) compared to control. The positive association were observed between homocysteine, Urea and Hs-CRP, IL_6 . It shows a significant Association of parameters in CRF . Conclusion: The results demonstrated elevation in plasma values IL-6 , homocysteine and HS-CRP in patients with CRF . However, these modifications may be lead to atherosclerosis and consequence CVD event. These parameters may be important with respect to the high morbidity and mortality of CVD found in patients with CRF.


ASAIO Journal ◽  
2006 ◽  
Vol 52 (2) ◽  
pp. 75A ◽  
Author(s):  
J Simoni ◽  
G Simoni ◽  
J F Moeller ◽  
A Khanna ◽  
W T Bohannon ◽  
...  

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