Adaptive learning algorithm in classification of fuzzy patterns An application to vowels in CNC context

1978 ◽  
Vol 9 (8) ◽  
pp. 887-897 ◽  
Author(s):  
S. K. PAL ◽  
A. K. DATTA ◽  
D. DUTTA MAJUMDER
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Gabriel A. Colozza-Gama ◽  
Fabiano Callegari ◽  
Nikola Bešič ◽  
Ana C. de J. Paviza ◽  
Janete M. Cerutti

AbstractSomatic mutations in cancer driver genes can help diagnosis, prognosis and treatment decisions. Formalin-fixed paraffin-embedded (FFPE) specimen is the main source of DNA for somatic mutation detection. To overcome constraints of DNA isolated from FFPE, we compared pyrosequencing and ddPCR analysis for absolute quantification of BRAF V600E mutation in the DNA extracted from FFPE specimens and compared the results to the qualitative detection information obtained by Sanger Sequencing. Sanger sequencing was able to detect BRAF V600E mutation only when it was present in more than 15% total alleles. Although the sensitivity of ddPCR is higher than that observed for Sanger, it was less consistent than pyrosequencing, likely due to droplet classification bias of FFPE-derived DNA. To address the droplet allocation bias in ddPCR analysis, we have compared different algorithms for automated droplet classification and next correlated these findings with those obtained from pyrosequencing. By examining the addition of non-classifiable droplets (rain) in ddPCR, it was possible to obtain better qualitative classification of droplets and better quantitative classification compared to no rain droplets, when considering pyrosequencing results. Notable, only the Machine learning k-NN algorithm was able to automatically classify the samples, surpassing manual classification based on no-template controls, which shows promise in clinical practice.


2021 ◽  
Vol 11 (3) ◽  
pp. 92
Author(s):  
Mehdi Berriri ◽  
Sofiane Djema ◽  
Gaëtan Rey ◽  
Christel Dartigues-Pallez

Today, many students are moving towards higher education courses that do not suit them and end up failing. The purpose of this study is to help provide counselors with better knowledge so that they can offer future students courses corresponding to their profile. The second objective is to allow the teaching staff to propose training courses adapted to students by anticipating their possible difficulties. This is possible thanks to a machine learning algorithm called Random Forest, allowing for the classification of the students depending on their results. We had to process data, generate models using our algorithm, and cross the results obtained to have a better final prediction. We tested our method on different use cases, from two classes to five classes. These sets of classes represent the different intervals with an average ranging from 0 to 20. Thus, an accuracy of 75% was achieved with a set of five classes and up to 85% for sets of two and three classes.


2021 ◽  
Vol 11 (9) ◽  
pp. 3836
Author(s):  
Valeri Gitis ◽  
Alexander Derendyaev ◽  
Konstantin Petrov ◽  
Eugene Yurkov ◽  
Sergey Pirogov ◽  
...  

Prostate cancer is the second most frequent malignancy (after lung cancer). Preoperative staging of PCa is the basis for the selection of adequate treatment tactics. In particular, an urgent problem is the classification of indolent and aggressive forms of PCa in patients with the initial stages of the tumor process. To solve this problem, we propose to use a new binary classification machine-learning method. The proposed method of monotonic functions uses a model in which the disease’s form is determined by the severity of the patient’s condition. It is assumed that the patient’s condition is the easier, the less the deviation of the indicators from the normal values inherent in healthy people. This assumption means that the severity (form) of the disease can be represented by monotonic functions from the values of the deviation of the patient’s indicators beyond the normal range. The method is used to solve the problem of classifying patients with indolent and aggressive forms of prostate cancer according to pretreatment data. The learning algorithm is nonparametric. At the same time, it allows an explanation of the classification results in the form of a logical function. To do this, you should indicate to the algorithm either the threshold value of the probability of successful classification of patients with an indolent form of PCa, or the threshold value of the probability of misclassification of patients with an aggressive form of PCa disease. The examples of logical rules given in the article show that they are quite simple and can be easily interpreted in terms of preoperative indicators of the form of the disease.


Cancers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1615
Author(s):  
Ines P. Nearchou ◽  
Hideki Ueno ◽  
Yoshiki Kajiwara ◽  
Kate Lillard ◽  
Satsuki Mochizuki ◽  
...  

The categorisation of desmoplastic reaction (DR) present at the colorectal cancer (CRC) invasive front into mature, intermediate or immature type has been previously shown to have high prognostic significance. However, the lack of an objective and reproducible assessment methodology for the assessment of DR has been a major hurdle to its clinical translation. In this study, a deep learning algorithm was trained to automatically classify immature DR on haematoxylin and eosin digitised slides of stage II and III CRC cases (n = 41). When assessing the classifier’s performance on a test set of patient samples (n = 40), a Dice score of 0.87 for the segmentation of myxoid stroma was reported. The classifier was then applied to the full cohort of 528 stage II and III CRC cases, which was then divided into a training (n = 396) and a test set (n = 132). Automatically classed DR was shown to have superior prognostic significance over the manually classed DR in both the training and test cohorts. The findings demonstrated that deep learning algorithms could be applied to assist pathologists in the detection and classification of DR in CRC in an objective, standardised and reproducible manner.


Author(s):  
Jianfang Cao ◽  
Minmin Yan ◽  
Yiming Jia ◽  
Xiaodong Tian ◽  
Zibang Zhang

AbstractIt is difficult to identify the historical period in which some ancient murals were created because of damage due to artificial and/or natural factors; similarities in content, style, and color among murals; low image resolution; and other reasons. This study proposed a transfer learning-fused Inception-v3 model for dynasty-based classification. First, the model adopted Inception-v3 with frozen fully connected and softmax layers for pretraining over ImageNet. Second, the model fused Inception-v3 with transfer learning for parameter readjustment over small datasets. Third, the corresponding bottleneck files of the mural images were generated, and the deep-level features of the images were extracted. Fourth, the cross-entropy loss function was employed to calculate the loss value at each step of the training, and an algorithm for the adaptive learning rate on the stochastic gradient descent was applied to unify the learning rate. Finally, the updated softmax classifier was utilized for the dynasty-based classification of the images. On the constructed small datasets, the accuracy rate, recall rate, and F1 value of the proposed model were 88.4%, 88.36%, and 88.32%, respectively, which exhibited noticeable increases compared with those of typical deep learning models and modified convolutional neural networks. Comparisons of the classification outcomes for the mural dataset with those for other painting datasets and natural image datasets showed that the proposed model achieved stable classification outcomes with a powerful generalization capacity. The training time of the proposed model was only 0.7 s, and overfitting seldom occurred.


2021 ◽  
Vol 237 ◽  
pp. 106718
Author(s):  
Sepideh Alsadat Azimi ◽  
Hossein Afarideh ◽  
Jong-Seo Chai ◽  
Martin Kalinowski ◽  
Abdelhakim Gheddou ◽  
...  

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