Alcohol Consumption Pattern and Serum Lipids in Alcoholic Cirrhosis and Pancreatitis

1984 ◽  
Vol 19 (5) ◽  
pp. 582-587 ◽  
Author(s):  
L. Stigendal ◽  
R. Olsson
Medicines ◽  
2021 ◽  
Vol 8 (7) ◽  
pp. 39
Author(s):  
Akihiko Shibamoto ◽  
Tadashi Namisaki ◽  
Junya Suzuki ◽  
Takahiro Kubo ◽  
Satoshi Iwai ◽  
...  

: Background: This study aimed to compare the diagnostic performance of carbohydrate-deficient transferrin (CDT) and gamma-glutamyltranspeptidase (γ-GTP) to assess the single and combined benefits of these biological markers for the detection of chronic excessive alcohol consumption in patients with alcoholic cirrhosis. Methods: Biological markers were determined in blood samples from patients with alcoholic cirrhosis (drinking group, n = 35; nondrinking group, n = 81). The prediction accuracy of %CDT alone, γ-GTP alone, and their combination for the detection of excessive alcohol consumption was determined in patients with alcoholic cirrhosis. Results: Serum total bilirubin, alanine aminotransferase, aspartate aminotransferase, γ-GTP, and alkaline phosphatase levels and %CDT were significantly higher and serum albumin levels were significantly lower in the drinking group than in the nondrinking group. The combination of %CDT and γ-GTP compared with %CDT or γ-GTP alone showed a higher prediction accuracy. The combination of %CDT and γ-GTP exhibited a higher specificity than γ-GTP alone. However, in terms of sensitivity, no significant difference was found between single or combined markers. Conclusions: The combination of %CDT and γ-GTP is considered a useful biomarker of chronic excessive alcohol consumption in patients with alcoholic cirrhosis.


Alcohol ◽  
2020 ◽  
Vol 89 ◽  
pp. 43-48
Author(s):  
Min-Gyu Yoo ◽  
Yoo Jeong Lee ◽  
Han Byul Jang ◽  
Hyo-Jin Kim ◽  
Hye-Ja Lee ◽  
...  

Author(s):  
Víctor J. Villanueva-Blasco ◽  
Verónica Villanueva Silvestre ◽  
Manuel Isorna ◽  
Patricia Motos ◽  
Pere Blay ◽  
...  

(1) The goal of this study was to analyze the prevalence and pattern of alcohol consumption (frequency of consumption, average daily consumption, and risky consumption) before and during confinement due to the coronavirus disease (COVID-19) in the adult population and based on gender. (2) Methods: Data from 3779 individuals were collected via a set of online surveys. The AUDIT alcohol consumption questions (AUDIT-C) were used to measure the frequency of consumption, the average daily consumption, intensive consumption, risky consumption, and standard drink units. (3) Results: During confinement, the prevalence of alcohol consumption declined in both males and females, but only intensive consumption showed significant differences, with a greater reduction in males. The number of females who consumed alcohol four or more times per week doubled, whereas the number of males who did so was multiplied by a factor of 1.5; in both females and males, the percentage who presented intensive consumption doubled. The percentage of females with risky consumption was higher than that of males both before and during confinement. In addition to gender, the interaction between age and the employment situation explain consumption before and during confinement. (4) Conclusions: During confinement due to COVID-19, alcohol consumption declined in both sexes, but alcohol-risk consumers increased their frequency of use. The interaction between gender, age, and employment situation was related to these changes. These findings are relevant for guiding public health and health-risk management policies related to alcohol consumption in environmental situations similar to COVID-19.


2019 ◽  
Vol 63 (2) ◽  
pp. 79-85
Author(s):  
Raisa Ya. Khamitova ◽  
D. V. Loskutov

Introduction. There are variable patterns of alcohol consumption in Russia that differ significantly between the regions. Awareness and knowledge of those regional differences are key to the effectiveness of measures to prevent and minimise possible damage to public health caused by alcohol consumption. The purpose. To identify regional characteristics of the dynamics of alcoholism and alcoholic psychosis and dependencies with indicators of the implementation and consumption of alcohol in Mari El in 2006-2017. Material and methods. In a retrospective analysis, they included state statistics and bulletins of the Office of Rospotrebnadzor on RME on the primary incidence and prevalence of alcohol dependence syndrome, chronic alcoholism, AP, acute alcohol poisoning, sales of alcohol through a distribution network in 2006-2017. Results. In the reported period of 2006-2017 there was a decline in determination coefficient (R2) from 0.76 to 0.96 for newly diagnosed cases of alcohol dependence in general, alcoholic psychosis and alcoholism in Mari El. There was a significant decline from 221.6 to 47.5 per 100 thousand in the range of values between regions, but higher rates remained among the rural and urban areas (p = 0.0002). The dynamics of the prevalence of alcoholic psychotic disorders and alcoholism were also on decline. Conclusion. The direction and extent of changes in the medical consequences of alcohol consumption (such as primary morbidity and prevalence of alcohol dependence syndrome, alcoholic psychosis and alcoholism, average duration of the course, number of alcoholic psychosis) in the region and indicators of the implementation and consumption of alcoholic beverages in the reported period can be evaluated as positive. It is crucial to ensure the positive trend in the alcohol consumption pattern and impact on public health in the region becomes a long-lasting one. At the same time, it is necessary to increase attention to the assistance and treatment provided to drug users patient.


2019 ◽  
Vol 2 (1-3) ◽  
pp. 8-15
Author(s):  
Chanita Unhapipatpong ◽  
Daruneewan Warodomwichit ◽  
Kumutnart Chanprapaph

A 54-year-old Thai female with known alcoholic cirrhosis presented with chronic scaly eczematous patches and plaque for over 1 month. Initially, she was treated with oral antibiotics, but the lesions did not improve. The dermatologic examination and history of alcoholic cirrhosis were compatible with zinc deficiency. Moreover, copper deficiency was found together with zinc deficiency. Excessive alcohol consumption can cause zinc and copper co-deficiency. To avoid aggravated copper deficiency after zinc supplementation, copper and zinc were supplemented together in appropriate proportions. On the 2-week follow-up examination, her clinical outcome improved.


2002 ◽  
Vol 37 (11) ◽  
pp. 1309-1312 ◽  
Author(s):  
S. Fujimori ◽  
T. Kishida ◽  
K. Mitsui ◽  
M. Yonezawa ◽  
K. Nagata ◽  
...  

2020 ◽  
pp. 1-2
Author(s):  
Bharathraj M. Y

Background : In case of ischemic hepatic disease, patients with severe heart failure usually remain asymptomatic, while for patients with congestive hepatopathy, signs of right-sided heart failure could mask hepatic injury. However, changes in hepatic function, that are proven by laboratory tests are significant¬ in predicting the survival of patients with severe heart failure. There is possible considerable changes in the involvement of cardiac morbidity among both alcoholics and non alcoholics. This study evaluates the cardiac profile of cirrhotic individuals with respect to their alcohol consumption. Materials and methods : It is a comparative cross sectional study carried out at Medical department of SSIMS and RC, a tertiary medical institute in central part of the Karnataka. Study randomly selected patients with cirrhosis which comprised of 50 alcoholics and 50 non alcoholics. A normal group of 50 individuals without history of alcohol consumption and cirrhosis were selected for secondary comparison. Non Probability Purposive Sampling Technique is used and data was analyzed using latest SPSS for windows. Results : ECHO revealed that all the patients with alcoholic and non alcoholic cirrhosis had abnormal LVIDd (>56mm). LV mass abnormality was found among 76% of patients with non alcoholic cirrhosis compared to 66% of patients with alcoholic cirrhosis. High Ejection fraction abnormality was found among only 4% of patients with non alcoholic cirrhosis. The abnormal E/A ratio was observed among 8% of patients with non alcoholic cirrhosis compared to 4% of alcoholic cirrhosis patients. Conclusion : 2D Echocardiography showed increase in LAD, LVIDd and LV mass among cirrhotic patients thereby suggesting definitive cardiac involvement. The cardiovascular abnormalities did not show much differences between the alcoholic and non alcoholic patients. all cirrhotic patients irrespective of their aetiology has to undergo a cardiovascular evaluation.


2020 ◽  
Vol 34 (6) ◽  
pp. 636-647 ◽  
Author(s):  
Zoé Bollen ◽  
Nicolas Masson ◽  
Samuel Salvaggio ◽  
Fabien D’Hondt ◽  
Pierre Maurage

Background: Attentional bias towards alcohol-related stimuli is a core characteristic of severe alcohol use disorders (AUD), directly linked to clinical variables (e.g. alcohol consumption, relapse). Nevertheless, the extent of this bias in subclinical populations remains poorly documented. This is particularly true for binge drinking, an alcohol consumption pattern highly prevalent in youth, characterised by an alternation between excessive intakes and withdrawal periods. Aims: We used eye-tracking to: (a) measure attentional bias in binge drinking, (b) determine its time course by dissociating early/late processing stages, (c) clarify its specificity for alcohol-related stimuli compared to other appetitive stimulations and (d) explore its modulation by current craving intensity. Methods: Binge drinkers ( n=42) and matched controls ( n=43) performed a visual probe task, requiring visual targets preceded by pairs of pictures to be processed, with three conditions (i.e. alcohol vs. soft drink, alcohol vs. high-calorie food, high-calorie food vs. low-calorie food). Results: No group difference was observed for early processing (i.e. first area of interest visited). Dwell times highlighted a bias towards soft drinks and healthy food among controls, without any global bias towards alcohol in binge drinkers. Centrally, a comparison of binge drinkers with low versus high current craving intensity indicated that binge drinking was associated with a bias towards alcohol and high-calorie food only in the presence of a high craving towards these stimuli. Conclusion: Attentional bias towards alcohol reported in severe AUD is only found in binge drinkers in the presence of high craving and is generalised to other appetitive cues.


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