Effect of correcting serum cholesterol levels on erectile function in patients with vasculogenic erectile dysfunction

2008 ◽  
Vol 42 (5) ◽  
pp. 437-440 ◽  
Author(s):  
Serkan Cevdet Gokkaya ◽  
Cuneyt Ozden ◽  
Ozdem Levent Ozdal ◽  
Hasbey Hakan Koyuncu ◽  
Ozer Guzel ◽  
...  
Keyword(s):  
Erectile Dysfunction ◽  
Serum Cholesterol ◽  
Erectile Function ◽  
Cholesterol Levels ◽  
Vasculogenic Erectile Dysfunction

Expression of the Apelin–APJ Pathway and Effects on Erectile Function in a Mouse Model of Vasculogenic Erectile Dysfunction

2013 ◽  
Vol 10 (12) ◽  
pp. 2928-2941 ◽  
Author(s):  
Mi‐Hye Kwon ◽  
Buyankhuu Tuvshintur ◽  
Woo Jean Kim ◽  
Hai‐Rong Jin ◽  
Guo Nan Yin ◽  
...  
Keyword(s):  
Erectile Dysfunction ◽  
Mouse Model ◽  
Erectile Function ◽  
Vasculogenic Erectile Dysfunction

956 THE EFFECT OF CORRECTION OF SERUM CHOLESTEROL LEVELS ON ERECTILE FUNCTION

2007 ◽  
Vol 6 (2) ◽  
pp. 261
Author(s):  
S. Gokkaya ◽  
C. Özden ◽  
L. Ozdal ◽  
H. Koyuncu ◽  
O. Guzel ◽  
...  
Keyword(s):  
Serum Cholesterol ◽  
Erectile Function ◽  
Cholesterol Levels

scholarly journals The Comparison of Penile Doppler Ultrasonography Findings with Serum Lipid Parameters in Hyperlipidemic Patients with Erectile Dysfunction

2021 ◽  
Author(s):  
Mustafa Taşdemir ◽  
Ünal Öztekin ◽  
Mehmet Canikoğlu ◽  
Hafize Aktaş
Keyword(s):  
Erectile Dysfunction ◽  
Erectile Function ◽  
Doppler Ultrasonography ◽  
Oral Treatment ◽  
Post Treatment ◽  
Cholesterol Levels ◽  
Before And After ◽  
Function Domain ◽  
Lipid Parameters ◽  
High Triglyceride

Objective: The aim of this study is to investigate the effect of hyperlipidemia on the development of erectile dysfunction (ED) in hyperlipidemic patients with ED. Materials and Methods: Twenty-five patients who applied to the radiology clinic were included in the study. All patients have only hyperlipidemia as a risk factor of ED. The patients were evaluated in terms of ED by using International Index of Erectile Function (IIEF) form. Before and after oral treatment with daily doses of 10 mg atorvastatin, all parameters were measured. Paired t-test was used to compare vascular velocities between lipid profiles and Erectile Function Domain Scores (EFDS) and IIEFs, before and after treatment separately. Results: Cholesterol levels of 96% of patients were higher than 200 mg/dl and 52% of them had abnormal penile Doppler ultrasonography (PDU) findings. Patients with abnormal PDU findings had lower cholesterol levels than those with normal PDU findings. Significant differences existed between patients with normal and abnormal PDU in the high triglyceride group as for pre-, and post-treatment values . Pre-, and post-treatment EFD and IIEF scores were comparable. Conclusion: It can be said that a relationship exists between hyperlipidemia and erectile dysfunction. Therefore, lipid profile of a patient admitted with ED may be analyzed routinely

scholarly journals Low-intensity extracorporeal shock wave therapy of vasculogenic erectile dysfunction - three-week treatment in a cohort of North Italian patients

2018 ◽  
Vol 146 (9-10) ◽  
pp. 549-553 ◽  
Author(s):  
Goran Arandjelovic ◽  
Fedra Gottardo ◽  
Ivan Ignjatovic
Keyword(s):  
Shock Wave ◽  
Erectile Dysfunction ◽  
Doppler Ultrasound ◽  
Erectile Function ◽  
Extracorporeal Shock Wave Therapy ◽  
Shock Wave Therapy ◽  
Low Intensity ◽  
Extracorporeal Shock Wave ◽  
Vasculogenic Erectile Dysfunction

Introduction/Objective. Although phosphodiesterase 5 (PDE 5) inhibitors represent the gold standard for medical treatment of erectile dysfunction (ED), they are not curative. Over the recent years, low-intensity extracorporeal shock wave therapy (LI-ESWT) has been proposed as a valid non-invasive therapy approach for ED. The aim of our work is to assess the shortened, three-week low-intensity extracorporeal shock wave therapy of vasculogenic ED. Methods. The study involved 32 patients with an International Index of Erectile Function (IIEF) score between 5 and 20, and whose vasculogenic ED had been proven through Doppler ultrasound. All the patients had a washout period of one month after previous therapy and agreed to discontinue the PDE5-I therapy during the follow-up. The LI-ESWT was applied for three weeks, twice weekly, without repeating. The patients were evaluated at baseline, after one, three, and six months with the IIEF, Doppler ultrasound, and the Beck Depression Inventory. Results. All investigated parameters (International Index of Erectile Function, Beck Depression Inventory and penile Doppler ultrasound parameters) showed statistically significant improvement just one month after the treatment, compared to pre-treatment values, in all investigated domains. The international index of erectile function passed from baseline values of 12.75 ? 4.62 to 14.87 ? 5.04 at one month after treatment (p < 0.01). This trend remained positive in IIEF and all the parameters tested at the three-month and six-month follow-up. Conclusion. The shortened three-week low-intensity shock wave treatment of vasculogenic erectile dysfunction proved to be clinically effective.

scholarly journals The Effect of Atorvastatin on ADMA Level and Erectile Function in patients with Vasculogenic Erectile Dysfunction

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
A Emam ◽  
M Abdallah ◽  
M Khalil
Keyword(s):  
Erectile Dysfunction ◽  
Normal Level ◽  
Erectile Function ◽  
Great Influence ◽  
Control Group ◽  
Adma Level ◽  
Short Term Treatment ◽  
Plasma Adma ◽  
Vasculogenic Erectile Dysfunction ◽  
Moderate Elevation

Abstract Background Erectile dysfunction (ED), the inability to achieve and/or maintain an erection sufficient to permit satisfactory intercourse, is a highly prevalent disease whose aetiology is mostly vasculogenic. It is associated with subclinical coronary artery disease (CAD) and is nowadays considered a marker of future cardiovascular events. The higher prevalence of ED in patients with cardiovascular risk factors(CVRF) reflects the underlying endothelial dysfunction. ADMA is a naturally occurring amino acid that exists as a result of proteolysis of methylated proteins. Several factors, such as oxidative stress and increased levels of low-density lipoproteins (LDLs), are responsible for induced production of ADMA in endothelial cells. In our study, atorvastatin administration resulted in a significant decrease in ADMA levels and improvement of erectile function Aim To demonstratethe effect of Atorvastatin on ADMA level and erectile function in patients with normal or high LDL level vasculogenic erectile dysfunction. Patients and Methods The study will include 30 patients aged 30-60 years old with vasculogenic erectile dysfunction.The patients will be collected from The Andrology Outpatient Clinic – Ain-Shams University Hospitals. Results Among the study group 10 subjects showed moderate elevation of plasma ADMA (33.3%), 10 subjects with high level (33.3%) and 10 subjects with normal level (33.3%), while in control group only 5 subjects had high ADMA level, one subjects with moderate elevation and 24 subjects had normal level (80%) There was high significant reduction in both ADMA and LDL level after atorvastatin treatment and significant improvement in IIEF score, However no significant change in Testosterone level CONCLUSIONS We demonstrated that short-term treatment with atorvastatin has great influence on plasma ADMA levels with marked improvement in lipid profile (LDL) and erectile function in both normolipidemic and dyslipidenic patients.

scholarly journals Can the International Index of Erectile Function (IIEF-5) be used as a diagnostic tool to the severity of vasculogenic erectile dysfunction?

2012 ◽  
Vol 17 (2) ◽  
pp. 101-104 ◽  
Author(s):  
Abdelrahman Elnashar ◽  
Amr M. Gadallah ◽  
Alaa A. Abdelaal ◽  
Islam F. Soliman ◽  
Mohamed A.F.M. Youssef
Keyword(s):  
Erectile Dysfunction ◽  
Diagnostic Tool ◽  
Erectile Function ◽  
Vasculogenic Erectile Dysfunction

scholarly journals Efficacy of Aspirin for Vasculogenic Erectile Dysfunction in Men: A Meta-Analysis of Randomized Control Trials

2020 ◽  
Vol 14 (5) ◽  
pp. 155798832096908
Author(s):  
Muhammad Irfan ◽  
Shaiful Bahari Ismail ◽  
Norhayati Mohd Noor ◽  
Nik Hazlina Nik Hussain
Keyword(s):  
Erectile Dysfunction ◽  
Erectile Function ◽  
Selection Criteria ◽  
Reference Lists ◽  
Meta Analysis ◽  
Vascular Disorder ◽  
Randomized Controlled ◽  
Randomized Control ◽  
High Selection ◽  
Vasculogenic Erectile Dysfunction

One of the major causes of erectile dysfunction (ED) is an endothelial vascular disorder. This meta-analysis is performed to determine the efficacy of aspirin on erectile function in men with vasculogenic ED. For this purpose, CENTRAL, MEDLINE, and reference lists of articles up to November 2019 were searched. Randomized controlled trials (RCTs) were selected that compared aspirin with placebo in men of any ethnicity with vasculogenic ED. A total of 58 trials were retrieved. Finally, two trials of 214 men fulfilled our selection criteria. High selection and detection bias were identified for one trial. The participants showed a significant improvement in erectile function when they took aspirin (mean difference: 5.14, 95% CI [3.89, 6.40], and I2 = 0%). Although the present meta-analysis suggested that aspirin has a significant effect on the improvement of erectile function, there were limited RCTs available on this topic and doses of aspirin varied. Additional studies are needed to support findings from this meta-analysis. Aspirin needs to be considered by practitioners when prescribing drugs for vasculogenic ED.

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