Women with Abnormal Mammographic Findings and High Neutrophil-to-Lymphocyte Ratio have the Worst Dietary Carbohydrate Quality Index

Abstract Background Dietary carbohydrate quality may play an important role in disease development. We evaluated the association between carbohydrate quality index (CQI) and the odds of metabolic syndrome (MetS) in type 2 diabetes mellitus (T2DM) subjects in Ghana. Methods In this case-control study, we analyzed data using 124 T2DM subjects. We obtained dietary information using 2-day 24-h dietary recalls. We calculated CQI from dietary fiber, glycemic index, whole grains/total grains ratio, and solid carbohydrates/total carbohydrates ratio. Serum lipid profiles were measured after an overnight fast of 8–12 h. Results Upon adjustments for the effects of covariates, the CQI showed a positive association with high-density lipoprotein cholesterol concentration (beta coefficient (β) = 0.24; standard error (SE) = 0.20; P for trend = 0.01), and an inverse relationship with waist circumference (β = − 17.29; SE = 4.00; P for trend < 0.001), systolic blood pressure (β = − 15.74; SE = 4.69; P for trend < 0.001), diastolic blood pressure (β = − 7.23; SE = 2.97; P for trend = 0.02), and triglyceride concentrations (β = − 0.43; SE = 0.11; P for trend < 0.001). Overall, the CQI had an inverse relationship with the odds of MetS (Odds ratio tertile 3 vs.1 0.05; 95% Confidence interval: 0.01–0.23; p-trend < 0.001). Also, a positive correlation was found between the CQI and fiber, but the CQI showed a negative relationship with dietary glycemic index. Conclusions The present results suggest an inverse association between the CQI of a diet and the odds of MetS. The CQI approach of dietary recommendation may be a useful strategy for dietary carbohydrate selection for the prevention of MetS.

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Dietary carbohydrate quality and risk of breast cancer among women

Nutrition Journal ◽

10.1186/s12937-021-00752-y ◽

2021 ◽

Vol 20 (1) ◽

Author(s):

Bahareh Sasanfar ◽

Fatemeh Toorang ◽

Elham Mohebbi ◽

Kazem Zendehdel ◽

Leila Azadbakht

Keyword(s):

Breast Cancer ◽

Quality Index ◽

Middle Eastern ◽

Menopausal Status ◽

Premenopausal Women ◽

Dietary Carbohydrate ◽

Dietary Fiber Intake ◽

Carbohydrate Quality ◽

Total Carbohydrates ◽

The Relationship

Abstract Background A few studies have examined the relationship between carbohydrate quality index (CQI) and risk of breast cancer (BC) among women in Middle Eastern countries. We studied the associations between carbohydrate quality index and the risk of BC in overall and by menopausal status. Methods In this case-control study, dietary intake of 461 women with pathologically confirmed BC within the past year were examined. The same information were collected for 495 apparently healthy controls using a 168-item validated FFQ. Carbohydrate quality was determined by considering four criteria including: ratio of solid carbohydrates to total carbohydrates, dietary fiber intake, GI and the ratio of whole grains to total grains. Results Mean GI and GL of participants were totally 57.5 ± 7.2 and 245.7 ± 64.7, respectively. A trend toward significant association was seen between GI and odds of BC in the whole population; such that after stratifying analysis by menopausal status, premenopausal women in the highest quartile of GI were 1.85 times higher likely to have BC than those in the lowest quartile (95% CI: 1.12, 3.07, P = 0.01). We found that women with the greatest CQI had lower odds for BC, compared with those with the lowest CQI (0.63; 95% CI: 0.43–0.94, P = 0.03). This association was remained after stratifying analysis by menopausal status in premenopausal (0.55; 95% CI: 0.34–0.90, P = 0.04). Conclusion We found that GI was directly and CQI inversely associated with odds of BC. In order to determine the effects of dietary carbohydrate quality prospective cohort studies are needed.

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Carbohydrate and Lipid Dietary Quality Indexes: Trends in the Brazilian Population

Current Developments in Nutrition ◽

10.1093/cdn/nzab053_009 ◽

2021 ◽

Vol 5 (Supplement_2) ◽

pp. 1016-1016

Author(s):

Luciana Cardoso ◽

Ana lúcia Rêgo ◽

Taís Lopes ◽

Natália Cardoso ◽

Iuna Alves ◽

...

Keyword(s):

Fatty Acids ◽

Rural Area ◽

Quality Index ◽

Brazilian Population ◽

Dietary Quality ◽

Dietary Carbohydrate ◽

Dietary Fiber Intake ◽

Carbohydrate Quality ◽

Nationally Representative ◽

Over Time

Abstract Objectives Our aim was to evaluate the qualitative profile of carbohydrate (CHO) and fat intake and the modification in 10-year period according to demographic and socioeconomic variables. Methods Data from two Brazilian National Dietary Survey with nationally representative sample of individuals ≥10 years old. The dietary Carbohydrate Quality Index (CQI) is a score ranging from 4 to 20 calculated from dietary fiber intake, global glycemic index, solid CHO to total CHO ratio and CHO from wholegrains to CHO from total grains ratio. Lipid Quality Index (LQI) was estimated by dividing the sum of the dietary content of monounsaturated and polyunsaturated fatty acids by the sum of saturated with trans fatty acids. Both indexes were categorized in quintiles in ascending order for best quality. Information about sex, age (categorized in adolescents, adults and elderly), income (quartiles), urban and rural area and lastly body mass index (categorized in obesity, overweight and normal/underweight) was collected. The estimates were generated separately for each survey and their 95% confidence intervals were compared to identify changes in time. Results CQI reduced in the Brazilian population, but was not significant. There was a significant reduction in the quintile of greater CHO quality over time for adolescentes (2,8%), first quartile of income (3,3%) and people living in rural área (5,3%). Otherwise the frequency of people that have better dietary quality for CHO increased for the last quartile of income (3,2%) over time. It was observed an increase for the population and for several categories at the second quintile for CQI, including men, adolescents, people in lowest quartile for income and people living in rural area. >The LQI raised 1,6% across 10 years in Brazilian population. It also increased between women (3,2%), adults (2,1%), last quartile of income (4,2%), urban area (2,2%) and obese (4,1%). Additionally, the frequency of people in the lowest quartile for income that presented the best quality in their diet for fats decreased 3,7% in 10 years. Conclusions Strategies to improve the dietary carbohydrate quality should be taken into consideration; particular attention should be given to dietary quality of carbohydrates and lipids of people with lowest income values in the Brazilian population. Funding Sources Not applicable.

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Clinical Impact of Myeloid-Derived Suppressor Cells, Lymphocyte Subsets, and Neutrophil-to-Lymphocyte Ratio in Patients with Colorectal Cancer

Laboratory Medicine Online ◽

10.3343/lmo.2020.10.1.75 ◽

2020 ◽

Vol 10 (1) ◽

pp. 75

Author(s):

Min-Gu Kang ◽

Chang Hyun Kim ◽

Soo Hyun Kim ◽

Jong-Hee Shin ◽

Hye Ran Kim ◽

...

Keyword(s):

Colorectal Cancer ◽

Lymphocyte Subsets ◽

Suppressor Cells ◽

Clinical Impact ◽

Neutrophil To Lymphocyte Ratio ◽

Myeloid Derived Suppressor Cells ◽

Lymphocyte Ratio

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Inflammation and Congenital Heart Disease Associated Pulmonary Hypertension

The Heart Surgery Forum ◽

10.1532/hsf.1228 ◽

2015 ◽

Vol 18 (1) ◽

pp. 038 ◽

Cited By ~ 2

Author(s):

Mete Gursoy ◽

Ece Salihoglu ◽

Ali Can Hatemi ◽

A. Faruk Hokenek ◽

Suleyman Ozkan ◽

...

Keyword(s):

Pulmonary Artery ◽

Pulmonary Artery Pressure ◽

Neutrophil To Lymphocyte Ratio ◽

Cell Distribution ◽

Inflammation Markers ◽

Distribution Width ◽

Artery Pressure ◽

Lymphocyte Ratio ◽

Mean Pulmonary Artery Pressure ◽

Pulmonary Arterial

Background: Increased blood flow may trigger pulmonary arterial wall inflammation, which may influence progression of pulmonary artery hypertension in patients with congenital heart disease. In this study, we aimed to investigate the correlation between preoperative inflammation markers and pulmonary arterial hypertension. Methods: A total of 201 patients with pulmonary hypertension were enrolled in this study retrospectively; they had undergone open heart surgery between January 2012 and December 2013. Patients’ preoperative C-reactive protein (CRP), neutrophil to lymphocyte ratio, red blood cell distribution width, pulmonary pressures, and postoperative outcomes were evaluated. Results: Patient age, neutrophil to lymphocyte ratio, red blood cell distribution width, and CRP were found to be significantly correlated with both preoperative peak and mean pulmonary artery pressures. These data were entered into a linear logistic regression analysis. Patient age, neutrophil to lymphocyte ratio, and CRP were found to be independently correlated with peak pulmonary pressure (P < .001, P < .001, and P = .004) and mean pulmonary artery pressure (P < .001, P < .001, and P = .001), whereas preoperative mean pulmonary artery pressure was found to be independently correlated with intensive care unit stay (P < .001). No parameter was found to be significantly correlated with extubation time and mortality. Eighteen patients had experienced pulmonary hypertensive crisis; in this subgroup, patients’ mean pulmonary artery pressure and neutrophil to lymphocyte ratio were found to be significant (P = .047, P = .003). Conclusion: Preoperative inflammation markers may be correlated with the progression of pulmonary hypertensive disease, but further studies with larger sample size are needed to determine the predictive role of these markers for postoperative outcomes.

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