The relationship between interpersonal problems and outcome in psychodynamic hospitalization-based treatment for personality disorders: A 12-month follow-up study

2010 ◽  
Vol 24 (4) ◽  
pp. 417-436 ◽  
Author(s):  
Patrick Luyten ◽  
Benedicte Lowyck ◽  
Rudi Vermote
Medicina ◽  
2021 ◽  
Vol 57 (6) ◽  
pp. 627
Author(s):  
Christina Frederiksen ◽  
Ole André Solbakken ◽  
Rasmus Wentzer Licht ◽  
Carsten René Jørgensen ◽  
Maria Rodrigo-Domingo ◽  
...  

Background and Objectives: Emotional dysfunction is considered a key component in personality disorders; however, only few studies have examined the relationship between the two. In this study, emotional dysfunction was operationalized through the Affect Integration Inventory, and the aim was to examine the relationships between the level of affect integration and the levels of symptom distress, interpersonal problems, and personality functioning in patients diagnosed with personality disorder according to the Diagnostic and Statistical Manual of Mental Disorders, fifth edition. Materials and Methods: Within a hospital-based psychiatric outpatient setting, 87 patients with personality disorder referred for treatment were identified for assessment with the Affect Integration Inventory and other measures (e.g., the Symptom Checklist-90, Revised, the Inventory of Interpersonal Problems 64 circumplex version, and the Severity Indices of Personality Problems). Results: The analyses revealed that problems with affect integration were strongly and statistically significantly correlated with high levels of symptom distress, interpersonal problems, and maladaptive personality functioning. Additionally, low scores on the Affect Integration Inventory regarding discrete affects were associated with distinct and differentiated patterns of interpersonal problems. Conclusion: Taken together, emotional dysfunction, as measured by the Affect Integration Inventory, appeared to be a central component of the pathological self-organization associated with personality disorder. These findings have several implications for the understanding and psychotherapeutic treatment of personality pathology. Furthermore, they highlight the importance of considering the integration of discrete affects and their specific contributions in the conceptualization and treatment of emotional dysfunction in patients with personality disorders.


2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii352-iii352
Author(s):  
Hung Tran ◽  
Robert Cooper

Abstract PURPOSE To describe decreased growth velocity with long term use of BRAFV600e and MEK inhibition in a patient with anaplastic ganglioglioma. RESULTS 4-year-old patient was found to have a 6 x 4.6 x 5 cm mass in the hypothalamus. Pathology consistent with anaplastic ganglioglioma and chromosomal microarray revealed a BRAFV600e mutation. Patient started on dabrafenib and trametinib and tumor decreased 85% after 3 months. She is stable without significant toxicities 39 months on therapy, and is now 8 years old. Patient had been growing at the 25% for weight and 12% for height but is now 65% for weight and 0.5% for height. It is difficult to tease out the relationship between the tumor, the location of the tumor, and the BRAF and MEK inhibitors and their effect on growth. Discussions with the family and endocrinology are ongoing but being <1% for height will lead to decrease in quality of life. CONCLUSIONS Further follow-up study is needed to determine if this is truly a long-term toxicity, or if this may just be a direct result of the location of the tumor. Would supplementation with growth hormone in this patient lead to losing control of a high grade tumor, or would it simply replace a hormone that is not produced?


2018 ◽  
Vol 110 ◽  
pp. 241-246 ◽  
Author(s):  
André Bonadias Gadelha ◽  
Silvia Gonçalves Ricci Neri ◽  
Martim Bottaro ◽  
Ricardo M. Lima

2021 ◽  
pp. 002076402110102
Author(s):  
Ruth Abraham ◽  
Marja Leonhadt ◽  
Lars Lien ◽  
Ingrid Hansen ◽  
Edvard Hauff ◽  
...  

Background: Women are more vulnerable to mental health problems than men after migration, but little is known about the influence of religiosity/spirituality on their quality of life. The purpose of this study was to explore religiosity/spirituality, in relationships with various domains of quality of life, among female Eritrean refugees staying in Norwegian asylum centres. Method: A questionnaire assessing sociodemographic characteristics was used together with the World Health OrganizationQuality of Life – Spirituality, Religiosity and Personal Beliefs (WHOQOL-SRPB) questionnaire, which assesses religiosity/spirituality and domains of quality of life. A total of 63 adult female Eritrean refugees who had been granted asylum but were still living in asylum reception centres located in southern and central Norway participated. Results: Religiosity/spirituality was independently associated with psychological quality of life ( B = 0.367, p < .001), level of independence ( B = 0.184, p = .028), social quality of life ( B = 0.500, p = .003), environmental quality of life ( B = 0.323, p < .001) and overall quality of life ( B = 0.213, p < .001), but not with physical quality of life ( B = 0.056, p = .679). There were no significant differences between religious affiliations on religiosity/spirituality or quality of life measures. Conclusion: Consistent with previous research, this study highlights the correlation between religiosity/spirituality and overall quality of life. We recommend a longitudinal follow-up study of similar populations, after they are resettled and integrated into their host countries, to understand the associations between quality of life and religiosity/spirituality over time.


2015 ◽  
Vol 38 (14) ◽  
pp. 1407-1414
Author(s):  
Juha Suuronen ◽  
Samu Sjöblom ◽  
Risto Honkanen ◽  
Heli Koivumaa-Honkanen ◽  
Heikki Kröger ◽  
...  

1965 ◽  
Vol 111 (472) ◽  
pp. 254-257 ◽  
Author(s):  
D. Laskowska ◽  
K. Urbaniak ◽  
A. Jus

The syndrome of acute catatonic delirium associated with fever and usually with a fatal outcome was reported over hundred years ago. The first to describe it was Calmeil in 1832 (cit. after Aronson and Thompson, 1950). Kraepelin (1904) includes these states in the group of “akute Verwirrtheit”. Most authors emphasize the acuteness and high mortality of these states. Thus Claude and Cuel (1927), Guiraud and Saunet (1938), Golse and Morel (1953), call them “délire aigu”, de Simone (1962) “catatonie pernicieuse”, Stauder (1934) “tödliche Katatonie”, Huber (1954) “lebens-bedrohliche Katatone psychosen”, Knoll (1954) “perniziose Katatonien”. English writers call them “acute lethal catatonia” (Fisher and Greiner, 1960), Scandinavian “delirium acutum” (Lingjaerde, 1954). In Russian journals one finds them described as “delirium acutum” (Agieeva et al., 1955; Molokhov, 1962), “ostrij bried” (Rohlenko, 1961) or more recently “hypertoxic schizophrenia” (Romasienko, 1962).


Stroke ◽  
2015 ◽  
Vol 46 (suppl_1) ◽  
Author(s):  
Takashi Yamazaki ◽  
Ken Nagata ◽  
Daiki Takano ◽  
Tetsuya Maeda

Background: Many genes and environmental factors linked to Alzheimer’s disease (AD) risk affect lipid metabolism or the cardiovascular system, strongly implicating cerebrovascular and metabolic dysfunction in AD pathogenesis. Although some PUFAs may improve cognitive function in aging individuals, it is still unclear how different PUFAs influence AD neuropathology and cognitive function. Objective: To examine the influence of polyunsaturated fatty acid (PUFA) metabolism on AD-associated cognitive decline, we investigated the relationship between serum PUFA profile and neuropsychological test performance. Methods: Cognitive functioning in patients with probable AD (n = 174, mean age 77.6 years) was examined using the Mini-Mental State Exam (MMSE) and clock drawing test (CDT). Serum samples were obtained for PUFA profile, including the eicosapentaenoic acid/arachidonic acid (EPA/AA) ratio, and measurement of brain natriuretic peptide (BNP) concentration. In the follow-up study, 47 subjects repeated MMSE and CDT after 1 year, According to the second MMSE score, the subjects were divided into the following 2 groups: those with unchanged or improved MMSE score and those with lower MMSE score. A receiver operating characteristic curve was used to evaluate the relationship between the EPA/AA ratio and 1-year cognitive stability. Results: In the cross-sectional study, total MMSE score correlated positively with the EPA/AA ratio and systolic blood pressure (SBP), and negatively with age and diastolic blood pressure (DBP) (p < 0.05). In the follow-up study, the MMSE score was lower than baseline in 20 subjects, whereas it was improved or unchanged in 29 patients. The EPA/AA ratio in the stable group was significantly greater than that in the deteriorating group, suggesting an association between higher EPA/AA ratio and cognitive stability over 1 year. The EPA/AA ratio predicted stability of cognitive performance with a sensitivity of 66% and specificity of 70% (odds ratio = 4.43) when the cut-off was 0.67. Conclusion: Our results suggest that serum EPA concentration strongly influences cognitive performances in AD patients. The EPA/AA ratio was a sensitive indicator of cognitive stability in this patient group.


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