Induction of cytochrome p‐450 and phosphatidylcholine synthesis by endosulfan in liver of rats : Effect of quality of dietary proteins

1985 ◽  
Vol 20 (6) ◽  
pp. 651-664 ◽  
Author(s):  
S.R. Tyagi ◽  
K. Sriram ◽  
Satya Narayan ◽  
U.K. Misra
Keyword(s):  
Dietary Proteins ◽  
Cytochrome P 450 ◽  
Phosphatidylcholine Synthesis

Patterns and Rates of Ammonia Excretion by Juvenile American Lobsters, Homarus americanus, Fed Casein- and Crab Protein-Based Diets

1986 ◽  
Vol 43 (6) ◽  
pp. 1290-1294 ◽  
Author(s):  
C. M. Hawkins ◽  
J. D. Castell ◽  
V. Leroyer
Keyword(s):  
Dietary Protein ◽  
Nutritional Quality ◽  
Ammonia Excretion ◽  
Homarus Americanus ◽  
Protein Formulation ◽  
Metabolic Status ◽  
Dietary Proteins ◽  
Formulated Diets ◽  
Excretion Rates

The rate of excretion of nitrogenous wastes is not only a function of an animal's metabolic status but is also a function of the nutritional quality and quantity of dietary protein. Hourly rates of ammonia excretion by Stage V and Stage VI juvenile lobsters, Homarus americanus, fed purified diets formulated with casein or a purified crab protein, were measured over 24 h postfeeding to evaluate differences in use efficiencies of these two dietary proteins. Hourly ammonia excretion rates by Stages V and VI lobsters fed the casein-based formulated diets were significantly higher than those of animals fed the crab protein formulation. In addition to differences in ammonia excretion rates observed between animals fed the two diets, regular but different recurring patterns in hourly excretion rates were found between Stages V and VI lobsters fed each diet. Our findings illustrate that although the percentage of protein in the food of juvenile lobsters may be similar, the use of the nitrogen component is significantly different. We conclude that the quality of the protein in a diet may be as important (if not more important) as its quantity.

scholarly journals Relationships between Nutritional Quality of Dietary Proteins and Hepatic Polyribosome Profiles in Rats

1980 ◽  
Vol 110 (3) ◽  
pp. 383-387 ◽  
Author(s):  
Hidehiko Yokogoshi ◽  
Yuko Sakuma ◽  
Akira Yoshida
Keyword(s):  
Nutritional Quality ◽  
Dietary Proteins

Dietary orotic acid accentuates the hepatic response to phenobarbital in rats

1990 ◽  
Vol 68 (9) ◽  
pp. 1146-1149 ◽  
Author(s):  
D. S. Milton Haines ◽  
Margaret Wu ◽  
Sonya D. Tokmakjian
Keyword(s):  
Endoplasmic Reticulum ◽  
Total Protein ◽  
Orotic Acid ◽  
Smooth Endoplasmic Reticulum ◽  
Limiting Factor ◽  
Semisynthetic Diet ◽  
Structural Framework ◽  
Cytochrome P 450 ◽  
Phosphatidylcholine Synthesis ◽  
Stimulation Of

In rats treated with phenobarbital for 3 days and simultaneously fed a semisynthetic diet containing 1.0% orotic acid, the extent of the increases in liver microsomal phosphatidylcholine, phosphatidylethanolamine, total RNA, total protein, and cytochrome P-450 were significantly greater than they were in rats treated identically with phenobarbital but without dietary orotic acid. This is attributed primarily to the stimulation of hepatic phosphatidylcholine synthesis by dietary orotic acid. In the absence of phenobarbital, orotic acid was shown to cause some increase in liver smooth endoplasmic reticulum components, but not cytochrome P-450. Orotic acid also decreased the activity of microsomal phosphatidylethanolamine N-methyltransferase, which may have contributed to the increase in the microsomal content of phosphatidylethanolamine. The hypothesis is advanced that phospholipid availability is a limiting factor in the hepatic response to phenobarbital. When more phospholipid is available to provide the structural framework for biogenesis of endoplasmic reticulum, all of the hepatic actions of phenobarbital, including induction of cytochrome P-450, are amplified.Key words: phosphatidylcholine, phosphatidylethanolamine, cytochrome P-450, phenobarbital, orotic acid, endoplasmic reticulum.

scholarly journals Effect of dietary proteins on insulin-like growth factor-1 (IGF-1) messenger ribonucleic acid content in rat liver

1992 ◽  
Vol 67 (2) ◽  
pp. 257-265 ◽  
Author(s):  
Yutaka Miura ◽  
Hisanori Kato ◽  
Tadashi Noguchi
Keyword(s):  
Growth Factor ◽  
Rat Liver ◽  
Soya Bean ◽  
Dietary Proteins ◽  
Insulin Like Growth Factor ◽  
Casein Diet ◽  
Mrna Species ◽  
Mrna Content ◽  
Protein Free Diet

Effects of quantity and quality of dietary proteins on plasma immunoreactive insulin-like growth factor-1 (IGF-1) concentration, and content of IGF-1 mRNA in rat liver were investigated in rats. Plasma immunoreactive IGF-1 concentration in rats given a casein diet was higher than that in rats given a soya-bean-protein or protein-free diet. The IGF-1 mRNA content in liver was estimated by the Northern blot hybridization technique employing 32P-labelled rat IGF-1 complementary DNA (cDNA). At least four molecular species of IGF-1 mRNA of different molecular weight were found in rat liver. The sizes were 0·8–1·2, 2·0, 3·6–4·0 and 7·4 kb. Most of the mRNA species decreased in the livers of rats given a gluten diet (120 g gluten/kg diet) compared with rats given the casein diet. In particular, mRNA of 7·4 kb decreased markedly. When rats were fed on the protein-free diet, mRNA of all species decreased significantly. The estimated IGF-1 mRNA in the livers of rats fed on the gluten or protein-free diet was almost 0·4 of that of the rats given the casein diet. Feeding the soya-bean-protein diet did not result in a marked effect on the hepatic content of mRNA species of IGF-1. The results showed that liver IGF-1 mRNA content is sensitively regulated by quantity and nutritional quality of dietary proteins.

Factors Influencing the Quality of Dietary Proteins: Implications for Pulses

2017 ◽  
Vol 94 (1) ◽  
pp. 49-57 ◽  
Author(s):  
Matthew G. Nosworthy ◽  
James D. House
Keyword(s):  
Dietary Proteins ◽  
Factors Influencing
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