Formulation of chitosan coated nanoliposomes for the oral delivery of colistin sulfate: in vitro characterization, 99mTc-radiolabeling and in vivo biodistribution studies

2021 ◽  
pp. 1-10
Author(s):  
Mohamed H. Aboumanei ◽  
Ashgan. F. Mahmoud ◽  
M. A. Motaleb
Keyword(s):  
Oral Delivery ◽  
In Vivo Biodistribution ◽  
Colistin Sulfate ◽  
In Vitro Characterization ◽  
Biodistribution Studies

In vitro binding and in vivo biodistribution studies of the neuroprotective peptide humanin using [125I]humanin derivatives

Peptides ◽  
2009 ◽  
Vol 30 (12) ◽  
pp. 2409-2417 ◽  
Author(s):  
Alexandra Evangelou ◽  
Christos Zikos ◽  
Dimitra Benaki ◽  
Maria Pelecanou ◽  
Penelope Bouziotis ◽  
...  
Keyword(s):  
In Vitro Binding ◽  
In Vivo Biodistribution ◽  
Biodistribution Studies ◽  
Vitro Binding

scholarly journals 124I-Radiolabeling of a Au(III)-NHC Complex for in Vivo Biodistribution Studies

2020 ◽  
Author(s):  
Federica Guarra ◽  
Alessio Terenzi ◽  
Christine Pirker ◽  
Rossana Passannante ◽  
Dina Baier ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Direct Evidence ◽  
Heterocyclic Carbenes ◽  
Emission Tomography ◽  
Direct Oxidation ◽  
In Vivo Biodistribution ◽  
Biodistribution Studies ◽  
Positron Emission

Au(III) complexes with N-Heterocyclic Carbenes (NHCs) ligands have shown remarkable potential as anticancer agents, yet their fate in vivo has not been thoroughly examined and understood. Herein we report on the synthesis of new Au(III)-NHC complexes via direct oxidation with radioactive [124I]I2 as a valuable strategy to monitor the in vivo biodistribution of this class of compounds using positron emission tomography (PET) and, in combination with in vitro analyses, to provide direct evidence of the importance of Au(III)-to-Au(I) reduction for achieving full anticancer activity.

Silica nanoparticles: Preparation, characterization and in vitro/in vivo biodistribution studies

2015 ◽  
Vol 71 ◽  
pp. 46-55 ◽  
Author(s):  
B.I. Tamba ◽  
A. Dondas ◽  
M. Leon ◽  
A.N. Neagu ◽  
G. Dodi ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
In Vivo Biodistribution ◽  
Biodistribution Studies
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