Structurally disordered C-terminal residues of GTP cyclohydrolase II are essential for its enzymatic activity

Journal of Biomolecular Structure and Dynamics ◽

10.1080/07391102.2021.1926326 ◽

2021 ◽

pp. 1-14

Author(s):

Savita Yadav ◽

Ranajit Nivrutti Shinde ◽

Suruchi Singh ◽

Subramanian Karthikeyan ◽

Balvinder Singh

Keyword(s):

Enzymatic Activity ◽

Gtp Cyclohydrolase ◽

Gtp Cyclohydrolase Ii

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Finding Ways to Relax: A Revisionistic Analysis of the Chemistry of E. coli GTP Cyclohydrolase II

Biochemistry ◽

10.1021/acs.biochem.1c00511 ◽

2021 ◽

Author(s):

Madison M. Smith ◽

Brett A. Beaupre ◽

Dariush C. Fourozesh ◽

Kathleen M. Meneely ◽

Audrey L. Lamb ◽

...

Keyword(s):

Gtp Cyclohydrolase ◽

E Coli ◽

Gtp Cyclohydrolase Ii

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A Novel Mechanism for Nitrosative Stress Tolerance Dependent on GTP Cyclohydrolase II Activity Involved in Riboflavin Synthesis of Yeast

Scientific Reports ◽

10.1038/s41598-020-62890-3 ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

Khairul Anam ◽

Ryo Nasuno ◽

Hiroshi Takagi

Keyword(s):

Stress Tolerance ◽

Nitrosative Stress ◽

Gtp Cyclohydrolase ◽

Gtp Cyclohydrolase Ii ◽

Riboflavin Synthesis

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GTP cyclohydrolase II and 3,4-dihydroxy-2-butanone 4-phosphate synthase are rate-limiting enzymes in riboflavin synthesis of an industrial Bacillus subtilis strain used for riboflavin production

Journal of Industrial Microbiology & Biotechnology ◽

10.1038/sj.jim.2900590 ◽

1999 ◽

Vol 22 (1) ◽

pp. 1-7 ◽

Cited By ~ 75

Author(s):

M Hümbelin ◽

V Griesser ◽

T Keller ◽

W Schurter ◽

M Haiker ◽

...

Keyword(s):

Bacillus Subtilis ◽

Subtilis Strain ◽

Gtp Cyclohydrolase ◽

Riboflavin Production ◽

Gtp Cyclohydrolase Ii ◽

Rate Limiting ◽

Riboflavin Synthesis ◽

Phosphate Synthase

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II. Yeast sequencing reports. The sequence of an 8·8 kb segment on the left arm of chromosome II fromSaccharomyces cerevisiae reveals four new open reading frames including homologs of animal DNA polymerase α-primases and bacterial GTP cyclohydrolase II

Yeast ◽

10.1002/yea.320100003 ◽

1994 ◽

Vol 10 (S1994A) ◽

pp. S13-S24 ◽

Cited By ~ 2

Author(s):

Luc van Dyck ◽

Bénédicte Purnelle ◽

André Goffeau ◽

Jacek Skala

Keyword(s):

Dna Polymerase ◽

Open Reading Frames ◽

Gtp Cyclohydrolase ◽

Dna Polymerase Α ◽

Gtp Cyclohydrolase Ii ◽

Chromosome Ii ◽

Reading Frames

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Assay for GTP Cyclohydrolase II Activity in Bacterial Extracts

BIO-PROTOCOL ◽

10.21769/bioprotoc.1198 ◽

2014 ◽

Vol 4 (15) ◽

Author(s):

Svetlana Yurgel ◽

Na Sa ◽

Jennifer Rice ◽

Sanja Roje

Keyword(s):

Gtp Cyclohydrolase ◽

Gtp Cyclohydrolase Ii

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Hemolytic properties and riboflavin synthesis of Helicobacter pylori: cloning and functional characterization of the rib A gene encoding GTP-cyclohydrolase II that confers hemolytic activity to Escherichia coli

Medical Microbiology and Immunology ◽

10.1007/s004300050062 ◽

1998 ◽

Vol 186 (4) ◽

pp. 177-187 ◽

Cited By ~ 13

Author(s):

S. Bereswill ◽

F. Fassbinder ◽

C. Völzing ◽

A. Covacci ◽

R. Haas ◽

...

Keyword(s):

Escherichia Coli ◽

Helicobacter Pylori ◽

Hemolytic Activity ◽

Functional Characterization ◽

Gtp Cyclohydrolase ◽

Gene Encoding ◽

Gtp Cyclohydrolase Ii ◽

Riboflavin Synthesis

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Structural and functional analysis of the riboflavin synthesis genes encoding GTP cyclohydrolase II (ribA), DHBP synthase (ribBA), riboflavin synthase (ribC), and riboflavin deaminase/reductase (ribD) fromHelicobacter pyloristrain P1

FEMS Microbiology Letters ◽

10.1111/j.1574-6968.2000.tb09339.x ◽

2000 ◽

Vol 191 (2) ◽

pp. 191-197 ◽

Cited By ~ 21

Author(s):

Frank Fassbinder ◽

Manfred Kist ◽

Stefan Bereswill

Keyword(s):

Functional Analysis ◽

Gtp Cyclohydrolase ◽

Genes Encoding ◽

Gtp Cyclohydrolase Ii ◽

Riboflavin Synthesis

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Molecular and structural characterization of GTP-cyclohydrolase II in Eremothecium ashbyi NRRL Y-1363: cDNA cloning, comparative sequence analysis and molecular modeling

Fungal Biology ◽

10.1016/j.funbio.2010.06.006 ◽

2010 ◽

Vol 114 (9) ◽

pp. 731-738 ◽

Cited By ~ 2

Author(s):

Sudeshna Sengupta ◽

T.S. Chandra

Keyword(s):

Molecular Modeling ◽

Sequence Analysis ◽

Cdna Cloning ◽

Structural Characterization ◽

Comparative Sequence Analysis ◽

Gtp Cyclohydrolase ◽

Comparative Sequence ◽

Eremothecium Ashbyi ◽

Gtp Cyclohydrolase Ii

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Biosynthesis of riboflavin in plants. The ribA gene of Arabidopsis thaliana specifies a bifunctional GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase

Phytochemistry ◽

10.1016/s0031-9422(00)00013-3 ◽

2000 ◽

Vol 53 (7) ◽

pp. 723-731 ◽

Cited By ~ 42

Author(s):

Stefan Herz ◽

Sabine Eberhardt ◽

Adelbert Bacher

Keyword(s):

Arabidopsis Thaliana ◽

Gtp Cyclohydrolase ◽

Gtp Cyclohydrolase Ii ◽

Phosphate Synthase

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The crystal structure reveals the molecular mechanism of bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II (Rv1415) fromMycobacterium tuberculosis

Acta Crystallographica Section D Biological Crystallography ◽

10.1107/s0907444913011402 ◽

2013 ◽

Vol 69 (9) ◽

pp. 1633-1644 ◽

Cited By ~ 6

Author(s):

Mirage Singh ◽

Pankaj Kumar ◽

Savita Yadav ◽

Ruchi Gautam ◽

Nidhi Sharma ◽

...

Keyword(s):

Crystal Structure ◽

Molecular Mechanism ◽

Gtp Cyclohydrolase ◽

Gtp Cyclohydrolase Ii ◽

Phosphate Synthase

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