Optimization and evaluation of silk fibroin-chitosan freeze-dried porous scaffolds for cartilage tissue engineering application

2016 ◽  
Vol 27 (7) ◽  
pp. 657-674 ◽  
Author(s):  
Varshini Vishwanath ◽  
Krishna Pramanik ◽  
Amit Biswas
2019 ◽  
Vol 69 (15) ◽  
pp. 961-970 ◽  
Author(s):  
Tatiane Venturott Toniato ◽  
Thiago Domingues Stocco ◽  
Danilo dos Santos Martins ◽  
Luciana Barros Santanna ◽  
Carla Roberta Tim ◽  
...  

2016 ◽  
Vol 4 (21) ◽  
pp. 3670-3684 ◽  
Author(s):  
Nandana Bhardwaj ◽  
Yogendra Pratap Singh ◽  
Dipali Devi ◽  
Raghuram Kandimalla ◽  
Jibon Kotoky ◽  
...  

A three-dimensional porous scaffolds based on muga silkworm, Antheraea assamensis was fabricated and well characterized for cartilage tissue engineering, which may present as noteworthy targets for the further development in chondrocytes based cartilage repair.


2017 ◽  
Vol 192 ◽  
pp. 44-47 ◽  
Author(s):  
Weiming Chen ◽  
Binbin Sun ◽  
Tonghe Zhu ◽  
Qiang Gao ◽  
Yosry Morsi ◽  
...  

2016 ◽  
Vol 872 ◽  
pp. 261-265 ◽  
Author(s):  
Wassanai Wattanutchariya ◽  
Atitaya Oonjai ◽  
Kittiya Thunsiri

This study reports the effects of the mixing ratio of hydroxyapatite (HA), silk fibroin (SF) and chitosan (CS) on the physical properties of the scaffold used in tissue engineering. Experimental design based on mixture design was implemented to investigate the degradation rate of the scaffolds fabricated from various ratios of those biomaterials. Furthermore, pore morphology and pore size were evaluated to confirm the compatibility of the scaffold topography for cell growth and adhesion. The results from the study showed that all ratios, except pure HA solution, can be fabricated into porous scaffolds with an interconnected pore structure and appropriate pore sizes to allow all types of human cells to pass through. Furthermore, the scaffold solutions with high CS ratio resulted in a uniform pore structure and lower rates of biodegradation. Therefore, CS is recommended as the main structure because it provides the highest resistance to biodegradation. The scaffolds from various ratios may be applied for different tissue replacements in the near future.


Biomaterials ◽  
2011 ◽  
Vol 32 (25) ◽  
pp. 5773-5781 ◽  
Author(s):  
Nandana Bhardwaj ◽  
Quynhhoa T. Nguyen ◽  
Albert C. Chen ◽  
David L. Kaplan ◽  
Robert L. Sah ◽  
...  

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