scholarly journals Estimation of an accuracy index of a diagnostic biomarker when the reference biomarker is continuous and measured with error

2016 ◽  
Vol 26 (6) ◽  
pp. 1111-1117 ◽  
Author(s):  
Mixia Wu ◽  
Dianchen Zhang ◽  
Aiyi Liu
2013 ◽  
Vol 34 (1) ◽  
pp. 32-40 ◽  
Author(s):  
Matthias Ziegler ◽  
Christoph Kemper ◽  
Beatrice Rammstedt

The present research aimed at constructing a questionnaire measuring overclaiming tendencies (VOC-T-bias) as an indicator of self-enhancement. An approach was used which also allows estimation of a score for vocabulary knowledge, the accuracy index (VOC-T-accuracy), using signal detection theory. For construction purposes, an online study was conducted with N = 1,176 participants. The resulting questionnaire, named Vocabulary and Overclaiming – Test (VOC-T) was investigated with regard to its psychometric properties in two further studies. Study 2 used data from a population representative sample (N = 527), and Study 3 was another online survey (N = 933). Results show that reliability estimates were satisfactory for the VOC-T-bias index and the VOC-T-accuracy index. Overclaiming did not correlate with knowledge, but it was sensitive to self-enhancement supporting the construct validity of the test scores. The VOC-T-accuracy index in turn covaried with general knowledge and even more so with verbal knowledge, which also supports construct validity. Moreover, the VOC-T-accuracy index had a meaningful correlation with age in both validation studies. All in all, the psychometric properties can be regarded as sufficient to recommend the VOC-T for research purposes.


2019 ◽  
Author(s):  
Julia Krupinova ◽  
Natalia Mokrysheva ◽  
Vasiliy Petrov ◽  
Ekaterina Pigarova ◽  
Anatoliy Tiulpakov ◽  
...  
Keyword(s):  

2019 ◽  
Vol 2 (1) ◽  
pp. 1-3
Author(s):  
Attabak Toofani Milani ◽  
Mahshid Mohammadian ◽  
Sadegh Rostaminasab ◽  
Roghayeh Paribananaem ◽  
Zohre Ahmadi ◽  
...  

Conventional diagnostic test have limitations to deferential diagnosis in clinical suspicion ofbacterial infection cases, that in some cases lead to inappropriate antibiotic therapy and increases antibiotic resistance. A new diagnostic insight is procalcitonin (PCT) test to improve diagnosis of bacterial infections and to guide antibiotic therapy. Serum PCT levels are of useful test as a biomarker in patients with bacterial infections for several reasons. Initial rise of PCT levels due to bacterial infection, subsequent sequential PCT levels can be used to assess the effectiveness and duration of antibiotic therapy. Based on clinical researches results, in bacterial infections, promising good results obtained when use of PCT used as differential diagnostic test. But further intervention studies are needed before use of PCT in clinical routine tests. The goal of this review is to study the PCT reliability as infections diagnostic biomarker.


2020 ◽  
Author(s):  
Jin Li ◽  
Deli Zhang ◽  
Kennedy Silva Ramos ◽  
Lucienne Baks ◽  
Marit Wiersma ◽  
...  

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