A proliferation-inducing ligand (APRIL) as a diagnostic biomarker of bacterial infection

2016 ◽  
Author(s):  
Tamara Tesic
Keyword(s):  
Bacterial Infection ◽  
Diagnostic Biomarker

Procalcitonin Testingreduce Unnecessary Antibiotic Use in Bacterial Infection

2019 ◽  
Vol 2 (1) ◽  
pp. 1-3
Author(s):  
Attabak Toofani Milani ◽  
Mahshid Mohammadian ◽  
Sadegh Rostaminasab ◽  
Roghayeh Paribananaem ◽  
Zohre Ahmadi ◽  
...  
Keyword(s):  
Antibiotic Therapy ◽  
Bacterial Infection ◽  
Diagnostic Test ◽  
Bacterial Infections ◽  
Intervention Studies ◽  
Antibiotic Use ◽  
Clinical Suspicion ◽  
Diagnostic Biomarker ◽  
Clinical Routine ◽  
Initial Rise

Conventional diagnostic test have limitations to deferential diagnosis in clinical suspicion ofbacterial infection cases, that in some cases lead to inappropriate antibiotic therapy and increases antibiotic resistance. A new diagnostic insight is procalcitonin (PCT) test to improve diagnosis of bacterial infections and to guide antibiotic therapy. Serum PCT levels are of useful test as a biomarker in patients with bacterial infections for several reasons. Initial rise of PCT levels due to bacterial infection, subsequent sequential PCT levels can be used to assess the effectiveness and duration of antibiotic therapy. Based on clinical researches results, in bacterial infections, promising good results obtained when use of PCT used as differential diagnostic test. But further intervention studies are needed before use of PCT in clinical routine tests. The goal of this review is to study the PCT reliability as infections diagnostic biomarker.

scholarly journals Interleukin-27 is a novel candidate diagnostic biomarker for bacterial infection in critically ill children

Critical Care ◽  
2012 ◽  
Vol 16 (5) ◽  
pp. R213 ◽  
Author(s):  
Hector R Wong ◽  
Natalie Z Cvijanovich ◽  
Mark Hall ◽  
Geoffrey L Allen ◽  
Neal J Thomas ◽  
...  
Keyword(s):  
Bacterial Infection ◽  
Critically Ill ◽  
Critically Ill Children ◽  
Diagnostic Biomarker ◽  
Interleukin 27

scholarly journals New diagnostic biomarker in acute diarrhea due to bacterial infection in children

2017 ◽  
Vol 4 (2) ◽  
pp. 75-80 ◽  
Author(s):  
Hassan M. Al-Asy ◽  
Rasha M. Gamal ◽  
Ahmed M. Abd Albaset ◽  
Mohammed G. Elsanosy ◽  
Maali M. Mabrouk
Keyword(s):  
Bacterial Infection ◽  
Acute Diarrhea ◽  
Diagnostic Biomarker

scholarly journals Procalcitonin Testingreduce Unnecessary Antibiotic Use in Bacterial Infection

2019 ◽  
Vol 2 (1) ◽  
pp. 1-3
Author(s):  
Attabak Toofani Milani ◽  
Mahshid Mohammadian ◽  
Sadegh Rostaminasab ◽  
Roghayeh Paribananaem ◽  
Zohre Ahmadi ◽  
...  
Keyword(s):  
Antibiotic Therapy ◽  
Bacterial Infection ◽  
Diagnostic Test ◽  
Bacterial Infections ◽  
Intervention Studies ◽  
Antibiotic Use ◽  
Clinical Suspicion ◽  
Diagnostic Biomarker ◽  
Clinical Routine ◽  
Initial Rise

Conventional diagnostic test have limitations to deferential diagnosis in clinical suspicion ofbacterial infection cases, that in some cases lead to inappropriate antibiotic therapy and increases antibiotic resistance. A new diagnostic insight is procalcitonin (PCT) test to improve diagnosis of bacterial infections and to guide antibiotic therapy. Serum PCT levels are of useful test as a biomarker in patients with bacterial infections for several reasons. Initial rise of PCT levels due to bacterial infection, subsequent sequential PCT levels can be used to assess the effectiveness and duration of antibiotic therapy. Based on clinical researches results, in bacterial infections, promising good results obtained when use of PCT used as differential diagnostic test. But further intervention studies are needed before use of PCT in clinical routine tests. The goal of this review is to study the PCT reliability as infections diagnostic biomarker.

scholarly journals Interleukin-27 as a candidate diagnostic biomarker for bacterial infection in immunocompromised pediatric patients

PLoS ONE ◽  
2018 ◽  
Vol 13 (11) ◽  
pp. e0207620 ◽  
Author(s):  
Lauren Jacobs ◽  
Zachary Berrens ◽  
Erin K. Stenson ◽  
Matthew Zackoff ◽  
Lara Danziger-Isakov ◽  
...  
Keyword(s):  
Bacterial Infection ◽  
Pediatric Patients ◽  
Diagnostic Biomarker ◽  
Interleukin 27

scholarly journals Serum Procalcitonin as a Diagnostic Biomarker for Bacterial Infection in Febrile Children

2017 ◽  
Vol 06 (01) ◽  
Author(s):  
Osama Y Safdar ◽  
Abdulmalik A Alghamdi ◽  
Duaa F Jastaniyyah ◽  
Daniya O Abdouh ◽  
Feras L AlKindi ◽  
...  
Keyword(s):  
Bacterial Infection ◽  
Diagnostic Biomarker

scholarly journals Clinical application of presepsin as diagnostic biomarker of infection: overview and updates

2019 ◽  
Vol 58 (1) ◽  
pp. 11-17 ◽  
Author(s):  
Emanuela Galliera ◽  
Luca Massaccesi ◽  
Elena de Vecchi ◽  
Giuseppe Banfi ◽  
Massimiliano M. Corsi Romanelli
Keyword(s):  
Intensive Care ◽  
Bacterial Infection ◽  
Pulmonary Infection ◽  
Immune Cell ◽  
Fungal Infections ◽  
Neonatal Infection ◽  
Diagnostic Biomarker ◽  
Infective Disease ◽  
Immune Cell Response ◽  
And Control

Abstract The appropriate identification of bacterial infection is the basis for effective treatment and control of infective disease. Among this context, an emerging biomarker of infection is presepsin (PSP), recently described as early marker of different infections. PSP secretion has been shown to be associated with monocyte phagocytosis and plasmatic levels of PSP increase in response to bacterial infection and decrease after antibiotic treatment, therefore it can be considered a marker of activation of immune cell response towards an invading pathogen. Different methods have been developed to measure PSP and this review will briefly describe the different clinical fields of application of PSP, ranging from intensive care to neonatal infection, to orthopedic and pulmonary infection as well as fungal infections and cardiovascular infections.

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