Recent progress on biocompatible nanocarrier-based genistein delivery systems in cancer therapy

2018 ◽  
Vol 27 (4) ◽  
pp. 394-407 ◽  
Author(s):  
Nisha Tyagi ◽  
Yo Han Song ◽  
Ranjit De
Keyword(s):  
Cancer Therapy ◽  
Recent Progress ◽  
Delivery Systems

scholarly journals Recent progress on nanoparticle-based drug delivery systems for cancer therapy

2017 ◽  
Vol 14 (3) ◽  
pp. 228 ◽  
Author(s):  
Yanru Xin ◽  
Mingming Yin ◽  
Liyuan Zhao ◽  
Fanling Meng ◽  
Liang Luo
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery Systems ◽  
Recent Progress ◽  
Delivery Systems

scholarly journals Recent progress in nanotechnology-based novel drug delivery systems in designing of cisplatin for cancer therapy: an overview

2019 ◽  
Vol 47 (1) ◽  
pp. 1674-1692 ◽  
Author(s):  
Muhammad Asim Farooq ◽  
Md Aquib ◽  
Anum Farooq ◽  
Daulat Haleem Khan ◽  
Mily Bazezy Joelle Maviah ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery Systems ◽  
Recent Progress ◽  
Delivery Systems ◽  
Novel Drug

Nanoparticle-based Drug Delivery Systems for Targeted Epigenetics Cancer Therapy

2020 ◽  
Vol 21 (11) ◽  
pp. 1084-1098
Author(s):  
Fengqian Chen ◽  
Yunzhen Shi ◽  
Jinming Zhang ◽  
Qi Liu
Keyword(s):  
Drug Delivery ◽  
Side Effects ◽  
Cancer Therapy ◽  
Drug Delivery Systems ◽  
Therapeutic Index ◽  
Delivery Systems ◽  
Epigenetic Therapy ◽  
Cancer Therapies ◽  
Therapeutic Benefits ◽  
High Therapeutic Index

This review summarizes the epigenetic mechanisms of deoxyribonucleic acid (DNA) methylation, histone modifications in cancer and the epigenetic modifications in cancer therapy. Due to their undesired side effects, the use of epigenetic drugs as chemo-drugs in cancer therapies is limited. The drug delivery system opens a door for minimizing these side effects and achieving greater therapeutic benefits. The limitations of current epigenetic therapies in clinical cancer treatment and the advantages of using drug delivery systems for epigenetic agents are also discussed. Combining drug delivery systems with epigenetic therapy is a promising approach to reaching a high therapeutic index and minimizing the side effects.

scholarly journals Targeting Pin1 for Modulation of Cell Motility and Cancer Therapy

Biomedicines ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 359
Author(s):  
Hsiang-Hao Chuang ◽  
Yen-Yi Zhen ◽  
Yu-Chen Tsai ◽  
Cheng-Hao Chuang ◽  
Ming-Shyan Huang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Tumor Suppressors ◽  
Protein Conformation ◽  
Genome Stability ◽  
Recent Progress ◽  
Multiple Roles ◽  
Cancer Development ◽  
Cancer Hallmarks ◽  
Underlying Mechanisms ◽  
And Function

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) specifically binds and isomerizes the phosphorylated serine/threonine-proline (pSer/Thr-Pro) motif, which leads to changes in protein conformation and function. Pin1 is widely overexpressed in cancers and plays an important role in tumorigenesis. Mounting evidence has revealed that targeting Pin1 is a potential therapeutic approach for various cancers by inhibiting cell proliferation, reducing metastasis, and maintaining genome stability. In this review, we summarize the underlying mechanisms of Pin1-mediated upregulation of oncogenes and downregulation of tumor suppressors in cancer development. Furthermore, we also discuss the multiple roles of Pin1 in cancer hallmarks and examine Pin1 as a desirable pharmaceutical target for cancer therapy. We also summarize the recent progress of Pin1-targeted small-molecule compounds for anticancer activity.

scholarly journals Personalized Medicine: Recent Progress in Cancer Therapy

Cancers ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 242
Author(s):  
Ann Hoeben ◽  
Elbert A. J. Joosten ◽  
Marieke H. J. van den Beuken-van Everdingen
Keyword(s):  
Cancer Therapy ◽  
Personalized Medicine ◽  
Precision Medicine ◽  
Recent Progress ◽  
Tumor Treatment ◽  
Treatment And Prevention

Personalized medicine (PM) or precision medicine in oncology is an emerging approach for tumor treatment and prevention that takes into account inter- and intra-tumor variability in genes, tumor (immune) environment, and lifestyle and morbidities of each person diagnosed with cancer [...]

Stimuli-Responsive Nano-Drug Delivery Systems for Cancer Therapy

2020 ◽  
pp. 151-162
Author(s):  
Sauraj ◽  
Anuj Kumar ◽  
Bijender Kumar ◽  
Ruchir Priyadarshi ◽  
Chhavi Sharma ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Stimuli Responsive ◽  
Nano Drug Delivery
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