Curcuma roscoeana Wall. is a tuberous perennial plant with tuberous rhizomes. It is an endangered species. In nature, it has a very low rate of multiplication. Propagation of C. roscoeana in vitro was done by culturing 0.5 × 1.0-mm shoot tips from young buds onto modified Murashige and Skoog (MS)+ 0.25 mg/L kinetin. Stem explants 10.0 mm in size, measured from the base of the plantlets longitudinally cut in half, were used in the experiments. The first experiment was done by varying the concentration of both kinetin and NAA, in MS liquid medium, at 0–8.0 mg/L and 0–0.05 mg/L, respectively. There were no significant differences of kinetin and NAA concentrations on the number of plantlets obtained. The 0.5-mg/L kinetin treatment gave the highest yield in number of new plantlets (3.1 plantlets/cultured explant). In the second experiment, various concentrations of BAP from 0 to 8.0 mg/l were tested. 2.8–3.7 plantlets were formed in the media with 0.05–2.0 mg/L of BAP. The most-suitable concentration of BAP was at 1.0 mg/L, providing 3.7 plantlets/cultured explants. Kinetin or BAP alone could be used in MS medium for rapid clonal propagation of C. roscoeana. The rooted plantlets could be successfully transferred into growing pots. Acknowledgement: The studies were supported in part by The King's Initiative Centre for Fruit and Flower propagation and Development, Ban Rai, Chiang Mai.