Chronic hypoxia promotes an aggressive phenotype in rat prostate cancer cells

2007 ◽  
Vol 41 (7) ◽  
pp. 788-797 ◽  
Author(s):  
Omar Alqawi ◽  
Hong P. Wang ◽  
Myrna Espiritu ◽  
Gurmit Singh
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Chronic Hypoxia ◽  
Prostate Cancer Cells ◽  
Aggressive Phenotype ◽  
Rat Prostate

OXIDATIVE STRESS IS INHERENT IN PROSTATE CANCER CELLS AND MEDIATES AGGRESSIVE PHENOTYPE

2008 ◽  
Vol 179 (4S) ◽  
pp. 192-193 ◽  
Author(s):  
Binod Kumar ◽  
Sweaty Koul ◽  
Lakshmipathi Khandrika ◽  
Randall B Meacham ◽  
Hari K Koul
Keyword(s):  
Oxidative Stress ◽  
Prostate Cancer ◽  
Cancer Cells ◽  
Prostate Cancer Cells ◽  
Aggressive Phenotype

A Study of Membrane Activity in Rat Prostate Cancer Cells: An Evaluation of the FM1–43 Dye Technique

2000 ◽  
Vol 20 (1) ◽  
pp. 31-40 ◽  
Author(s):  
Maria E. Mycielska ◽  
Monika Schäfer ◽  
Scott P. Fraser ◽  
Mustafa B. A. Djamgoz ◽  
C. Lindsay Bashford
Keyword(s):  
Prostate Cancer ◽  
Cell Division ◽  
Cancer Cells ◽  
Cell Lines ◽  
Prostate Cancer Cells ◽  
Excitable Cells ◽  
Membrane Activity ◽  
Variable Pattern ◽  
Cells In Culture ◽  
Rat Prostate

A study was initiated to test whether the FM1–43 dye technique could beapplied to the study of endocytic membrane activity in two rodent prostatecancer (MAT-LyLu and AT-2) cell lines of markedly different metastaticability. The lipophilic dye FM1–43, which has frequently been used tomonitor endo/exocytic activity in excitable cells was employed. We found,as in excitable tissues, that both strongly metastatic (MAT-LyLu) andweakly metastatic (AT-2) cells in culture take up FM1–43 to give vesicularstaining of a variable pattern, which appeared to differ between the twocell lines. However, unlike excitable tissues, neither cell linesubsequently released the dye. Indeed, both cell lines retained the dyethrough several rounds of cell division suggesting that dye incorporatedby cells does not enter the endo/exocytotic cycle. Uptake of dye wasindependent of temperature, Na+/K+ gradients, pH or metabolism. Wesuggest that passive accumulation of FM1–43 can occur in cancer cells andshould not, automatically, be interpreted as evidence of endocytosis.

A short peptide reverses the aggressive phenotype of prostate cancer cells

2018 ◽  
Vol 838 ◽  
pp. 129-137
Author(s):  
Hongjiao Liu ◽  
Xiaomian Lin ◽  
Tao Huang ◽  
Li Song ◽  
Cairong Zhu ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Prostate Cancer Cells ◽  
Short Peptide ◽  
Aggressive Phenotype

Abstract 351: HO-1 modulates the actin stress fiber architecture in prostate cancer cells: Towards a less aggressive phenotype

2015 ◽  
Author(s):  
Alejandra V. Paez ◽  
Carla Pallavicini ◽  
Jimena Giudice ◽  
Noelia Carabelos ◽  
Nicolas Anselmino ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Stress Fiber ◽  
Actin Stress Fiber ◽  
Fiber Architecture ◽  
Prostate Cancer Cells ◽  
Aggressive Phenotype

The Vav3 oncogene enhances the malignant potential of prostate cancer cells under chronic hypoxia

2014 ◽  
Vol 32 (2) ◽  
pp. 101-109 ◽  
Author(s):  
Kenichi Hirai ◽  
Takeo Nomura ◽  
Mutsushi Yamasaki ◽  
Toru Inoue ◽  
Takahiro Narimatsu ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Chronic Hypoxia ◽  
Malignant Potential ◽  
Prostate Cancer Cells

scholarly journals Acidosis induces multi-drug resistance in rat prostate cancer cells (AT1)in vitroandin vivoby increasing the activity of the p-glycoproteinviaactivation of p38

2008 ◽  
Vol 123 (11) ◽  
pp. 2532-2542 ◽  
Author(s):  
Christoph Sauvant ◽  
Martin Nowak ◽  
Claudia Wirth ◽  
Bettina Schneider ◽  
Anne Riemann ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Drug Resistance ◽  
Cancer Cells ◽  
Multi Drug Resistance ◽  
Prostate Cancer Cells ◽  
Rat Prostate

Rat Prostate Cancer Cells Contain Functional Receptors for Transforming Growth Factorβ*

Endocrinology ◽  
1990 ◽  
Vol 126 (2) ◽  
pp. 818-825 ◽  
Author(s):  
SYDNEY A. SHAIN ◽  
ALAN L. LIN ◽  
JUDITH D. ROGER ◽  
ANDREW G. KARAGANIS
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Prostate Cancer Cells ◽  
Rat Prostate
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