Abstract
Objective
Intra-individual variability (IIV) has been associated with cognitive dysfunction and traumatic brain injury (TBI) severity. This study examined IIV in physical medicine and rehabilitation patients grouped by TBI severity and performance validity.
Method
Participants (N = 213) were 32% female and 90% white with average age and education of 42 (SD = 13) and 14 (SD = 2) years, respectively. Participants completed an outpatient evaluation using a flexible battery of up to 33 common neuropsychological measures. Participants were grouped by TBI severity and validity: mild (32%), moderate (14%), severe (32%), and questionable performance validity (QPV; 22%). QPV was determined on the basis of embedded and freestanding validity measures. Test battery scores were converted to T scores. Cases with four or more scores below 36 T were identified as impaired. Measures of IIV were calculated including overall test battery mean (OTBM), test battery standard deviation (SD), kurtosis, skew, range, and unbiased coefficient of variation (UCV). IIV measures were compared across groups.
Results
Groups were significantly different in OTBM (p < .001), kurtosis (p < .03), and UCV (p < .001). In valid cases, TBI severity was associated with OTBM (rho = −.31), SD (.19), kurtosis (−.16), and UCV (.33). Impaired and unimpaired cases were significantly different in OTBM (p < .001), SD (p < .001), range (p < .01), and UCV (p < .001). QPV cases were similar to impaired cases on measures of IIV.
Conclusions
IIV measures have potential clinical utility in characterizing cognitive deficits in TBI and warrant further study.