Higher serum level of CTRP15 in patients with coronary artery disease is associated with disease severity, body mass index and insulin resistance

Author(s):  
Abolfazl Shokoohi Nahrkhalaji ◽  
Reza Ahmadi ◽  
Reza Fadaei ◽  
Ghodratollah Panahi ◽  
Malihe Razzaghi ◽  
...  
2014 ◽  
Vol 167 (4) ◽  
pp. 514-520 ◽  
Author(s):  
Caleb M. Stalls ◽  
Matthew A. Triplette ◽  
Anthony J. Viera ◽  
Donald E. Pathman ◽  
Mauricio G. Cohen ◽  
...  

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 449-P
Author(s):  
TAKESHI KOMATSU ◽  
KAZUYA FUJIHARA ◽  
MAYUKO H. YAMADA ◽  
TAKAAKI SATO ◽  
MASARU KITAZAWA ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Anne B. Gregory ◽  
Kendra K. Lester ◽  
Deborah M. Gregory ◽  
Laurie K. Twells ◽  
William K. Midodzi ◽  
...  

Background and Aim. Obesity is associated with an increased risk of cardiovascular disease and may be associated with more severe coronary artery disease (CAD); however, the relationship between body mass index [BMI (kg/m2)] and CAD severity is uncertain and debatable. The aim of this study was to examine the relationship between BMI and angiographic severity of CAD. Methods. Duke Jeopardy Score (DJS), a prognostic tool predictive of 1-year mortality in CAD, was assigned to angiographic data of patients ≥18 years of age (N=8,079). Patients were grouped into 3 BMI categories: normal (18.5–24.9 kg/m2), overweight (25.0–29.9 kg/m2), and obese (≥30 kg/m2); and multivariable adjusted hazard ratios for 1-year all-cause and cardiac-specific mortality were calculated. Results. Cardiac risk factor prevalence (e.g., diabetes, hypertension, and hyperlipidemia) significantly increased with increasing BMI. Unadjusted all-cause and cardiac-specific 1-year mortality tended to rise with incremental increases in DJS, with the exception of DJS 6 (p<0.001). After adjusting for potential confounders, no significant association of BMI and all-cause (HR 0.70, 95% CI .48–1.02) or cardiac-specific (HR 1.11, 95% CI .64–1.92) mortality was found. Conclusions. This study failed to detect an association of BMI with 1-year all-cause or cardiac-specific mortality after adjustment for potential confounding variables.


Heart Asia ◽  
2015 ◽  
Vol 7 (2) ◽  
pp. 12-18 ◽  
Author(s):  
Hirofumi Hioki ◽  
Takashi Miura ◽  
Hirohiko Motoki ◽  
Hideki Kobayashi ◽  
Masanori Kobayashi ◽  
...  

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