Two new secondary metabolites from the mangrove endophytic fungus Pleosporales sp. SK7

2019 ◽  
Vol 34 (20) ◽  
pp. 2919-2925 ◽  
Author(s):  
Shitong Wen ◽  
Weilong Fan ◽  
Huixian Guo ◽  
Cuiying Huang ◽  
Zhangyuan Yan ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Endophytic Fungus ◽  
Mangrove Endophytic Fungus

scholarly journals Secondary Metabolites of a Mangrove Endophytic Fungus Aspergillus terreus (No. GX7-3B) from the South China Sea

Marine Drugs ◽  
2013 ◽  
Vol 11 (7) ◽  
pp. 2616-2624 ◽  
Author(s):  
Chun-Mei Deng ◽  
Shi-Xin Liu ◽  
Cai-Huan Huang ◽  
Ji-Yan Pang ◽  
Yong-Cheng Lin
Keyword(s):  
Secondary Metabolites ◽  
South China Sea ◽  
South China ◽  
Endophytic Fungus ◽  
Aspergillus Terreus ◽  
The South China Sea ◽  
The South ◽  
China Sea ◽  
Mangrove Endophytic Fungus

scholarly journals Secondary Metabolites with α-Glucosidase Inhibitory Activity from Mangrove Endophytic Fungus Talaromyces sp. CY-3

Marine Drugs ◽  
2021 ◽  
Vol 19 (9) ◽  
pp. 492
Author(s):  
Wencong Yang ◽  
Qi Tan ◽  
Yihao Yin ◽  
Yan Chen ◽  
Yi Zhang ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
13C Nmr ◽  
Inhibitory Activity ◽  
Endophytic Fungus ◽  
Spectroscopic Data ◽  
Positive Control ◽  
Mangrove Endophytic Fungus ◽  
Chemical Hydrolysis ◽  
Ic50 Value ◽  
New Compounds

Eight new compounds, including two sambutoxin derivatives (1–2), two highly oxygenated cyclopentenones (7–8), four highly oxygenated cyclohexenones (9–12), together with four known sambutoxin derivatives (3–6), were isolated from semimangrove endophytic fungus Talaromyces sp. CY-3, under the guidance of molecular networking. The structures of new isolates were elucidated by analysis of detailed spectroscopic data, ECD spectra, chemical hydrolysis, 13C NMR calculation, and DP4+ analysis. In bioassays, compounds 1–5 displayed better α-glucosidase inhibitory activity than the positive control 1-deoxynojirimycin (IC50 = 80.8 ± 0.3 μM), and the IC50 value was in the range of 12.6 ± 0.9 to 57.3 ± 1.3 μM.

scholarly journals Secondary Metabolites from the Mangrove Endophytic Fungus Penicillium sp. (SBE-8)

2009 ◽  
Vol 4 (11) ◽  
pp. 1934578X0900401 ◽  
Author(s):  
Zhiyong Guo ◽  
Fan Cheng ◽  
Kun Zou ◽  
Junzhi Wang ◽  
Zhigang She ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Cell Lines ◽  
Endophytic Fungus ◽  
Spectroscopic Methods ◽  
Penicillium Sp ◽  
Mtt Method ◽  
Mangrove Endophytic Fungus

A new metabolite, 7-hydroxyjanthinone (1), was isolated from the mangrove endophytic fungus Penicillium sp. (SBE-8), together with two known compounds, janthinone (2) and citrinin (3). The structures of these compounds were identified by spectroscopic methods. Compounds 1 and 2 showed no cytotoxicity against KB and KBv cell lines when tested by the MTT method, but compound 3 was weakly active.

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