Utilization of Red Apple Peel Extract in Dyeing of Wool Fabric

2021 ◽  
pp. 1-14
Author(s):  
Hosam El-sayed ◽  
Nagla El-Shemy
Keyword(s):  
Author(s):  
Nurarita Fadila Zesiorani ◽  
Effionora Anwar

Objective: This study aims to formulate and characterize a transfersome apple peel extract, formulate it into a gel, and compare it with a control gelmade without transfersome.Methods: Both gels were evaluated, stability tested, and penetration tested using Franz diffusion cells on the skin of female Sprague-Dawley rats. Thetransfersome preparations were formulated with different concentrations of the active substance, quercetin: 0.5% (F1); 0.7% (F2), and 1.0% (F3).Results: Based on the characterization results, F1 was selected as the optimum gel formulation because it had spherical morphology, a Dmean volume of106.44±2.70 nm, a polydispersity index of 0.078±0.01, a zeta potential of −49.96±2.05 mV, and a drug efficiency entrapment percentage of 78.78±0.46%.The cumulative amount of quercetin that was penetrated with the transfersome gel was 1514.41±26.31 μg/cm2, whereas the penetration with thecontrol gel extract was 1133.62±18.96 μg/cm2. The cumulative percentages of the penetrated gel transfersome and gel extract were 78.40±1.89%and 49.89±0.88%, respectively. The fluxes of transfersome gel and control gel extract were 52.33±0.11 μg/cm²/hrs and 40.89±0.68 μg/cm²/hrs,respectively.Conclusions: Based on these results, it can be concluded that the gel with transfersome exhibited better penetration than the gel extract alone.


2003 ◽  
Vol 279 (11) ◽  
pp. 10670-10676 ◽  
Author(s):  
Min Ding ◽  
Yongju Lu ◽  
Linda Bowman ◽  
Chuanshu Huang ◽  
Stephen Leonard ◽  
...  

2012 ◽  
Vol 135 (4) ◽  
pp. 2320-2325 ◽  
Author(s):  
Nileeka Balasuriya ◽  
H.P. Vasantha Rupasinghe

2020 ◽  
Vol 63 (2) ◽  
pp. 117-123 ◽  
Author(s):  
Eun-Ho Lee ◽  
Hye-Jin Park ◽  
Byung-Oh Kim ◽  
Hyong-Woo Choi ◽  
Kyeung-Il Park ◽  
...  

Author(s):  
Retno Susilowati ◽  
Jauharotul Jannah ◽  
Zahrotul Maghfuroh ◽  
MeikeTiya Kusuma

Author(s):  
Abdul Mudabbir Rehan

Introduction: The Chemotherapy-Induced Anemia (CIA) is a complex phenomenon impacted by many treatments and patient related variables. Some variations within CIA are type of chemotherapeutic agent, dose and schedule of administration of agent, type as well as stage of cancer, time of intervention, age, gender, nutritional status and renal function. The variety of patient presentation and symptomatology in CIA is very thought-provoking while setting up widespread measures to oversee ideal administration of treatments. This study will be focused on protective role of apple peel extract (APPE) on carboplatin induced fall in blood RBC count bone marrow erythroid cell percentage in mice. Aims & Objective: To evaluate the protective effect of Malus domestica peel extract on carboplatin induced fall in red blood cell count and bone marrow erythroid cell percentage in mice. Place and duration of study: The study was conducted at Pharmacology Department of Postgraduate Medical institute, Lahore in June 2016. The total duration of study was 1 month. Material & Methods: Forty adult male mice were randomly divided into 5 groups (n=8) and maintained on standard diet and water adlibitum. Group A was negative control. Group B was disease control wherein each animal received one dose of 125mg/kg carboplatin intraperitoneally. Group C, D & E experimental groups were administered same dose carboplatin followed by the ethanolic apple peel extract in three different single oral doses of 25, 50 & 75mg/kg respectively for 7 days. Blood & tissue sampling was done on the 8th day. Data was analyzed using Graf Pad prism 7. Results: Acute Carboplatin anaemia resulted in 4.01±0.851012/L RBC Count & 21.6±1.06% bone marrow erythroid cell percentage in Disease Control Group B. Subsequent Apple peel extract administration in a dose of 25, 50 and 75mg/kg\ countered carboplatin induced fall in Groups C, D & E, simultaneously raising RBC counts & bone marrow erythroid cell percentage to (6.19±0.70×1012/L & 21.3±1.28%) (6.56±0.37×1012/L & 25.3±1.04%) and (6.26±0.74×1012/L & 23.5±1.41%.) respectively. The increase in RBC as well as erythroid cell counts was most significant with the dose of 50mg/kg and nearing that of healthy control levels (Group A) Conclusion: Apple Peel Extract effectively prevented carboplatin induced fall in RBC count and erythroid cell percentage and produced most significant results in a dose of 50 mg/kg.


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