scholarly journals Child deaths at National District Hospital, Free State: one a month is better than one a week

2017 ◽  
Vol 59 (5) ◽  
pp. 172-174
Author(s):  
H Brits
Keyword(s):  
District Hospital ◽  
Free State ◽  
Child Deaths ◽  
Better Than

scholarly journals Women who give birth before arriving at National District Hospital in Bloemfontein, Free State

2017 ◽  
Vol 59 (6) ◽  
pp. 228-229
Author(s):  
A Beukes ◽  
T Mabasa ◽  
L Mkhungo ◽  
C Olivier ◽  
N Ramoo ◽  
...  
Keyword(s):  
District Hospital ◽  
Free State

scholarly journals 771. Prospective validation of the universal vital assessment (UVA) score to predict the in-hospital mortality of patients with acute illness admitted to a government district hospital in KwaZulu-Natal, South Africa

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S430-S430
Author(s):  
Amiya A Ahmed ◽  
Joseph B Ladines-Lim ◽  
Christopher Moore ◽  
Sipho Malinga ◽  
Anthony Moll ◽  
...  
Keyword(s):  
South Africa ◽  
High Risk ◽  
District Hospital ◽  
Characteristic Curve ◽  
Predictive Ability ◽  
Roc Curves ◽  
Routine Care ◽  
Resource Limited ◽  
Tract Infections ◽  
Better Than

Abstract Background Critical illness is a frequent cause of mortality in resource-limited settings. Improved triage on admission could improve mortality, but existing tools depend on variables that often are not available. We prospectively evaluated the universal vital assessment (UVA) score to predict mortality among patients admitted to a district hospital in rural, highly HIV-prevalent South Africa. Figure 1. Receiver operator characteristic (ROC) curves for the UVA and qSOFA scoring tools. Methods In February-March 2020, adults admitted to the medical wards were enrolled, prior to interruption by covid19, and 30-day mortality assessed. Clinical parameters including temperature, heart and respiratory rates, systolic blood pressure, oxygen saturation, Glasgow Coma Scale score, and HIV status were collected within 24 hours of admission as part of routine care. Lower respiratory tract infections (LRTI) included pneumonia and suspected pulmonary tuberculosis. To evaluate the predictive ability of the UVA score, area under the receiver operating characteristic curve (aROC) and age-sex adjusted binary logistic regression models were generated, and compared to the sequential organ failure assessment (qSOFA). Results Sixty one patients were enrolled; outcomes were available for 56 patients. Patients had a mean age of 52 (SD+17), 51% were women, and 46% were HIV infected. The 30-day mortality was 16.1% (9/56) with infections and non-communicable diseases comprising 47% and 47% of admission diagnoses, respectively. The most common admitting diagnosis was LRTI (24.6%). The median (+IQR) UVA score was 2 (+3) accounting for 36% of participants. Medium-risk (2-4) and high-risk (>4) UVA groups were not associated with 30-day mortality, although the high-risk score trended towards significance (p=0.07). However, a UVA score > 3 was significantly associated with 30-day mortality, both alone and after adjusting for age and sex (aOR 6.2, 95% CI 1.2-33.1; p=0.03). The aROC (95% CI) for the UVA score was 0.74 (0.55 – 0.93), which performed better than qSOFA (aROC 0.59, 95% CI 0.37-0.81) and is shown in Figure 1. Conclusion In this resource-limited, HIV-prevalent setting, the UVA score predicted mortality better than the qSOFA score. A moderate-risk UVA score (>3) was predictive of 30-day mortality, though needs to be confirmed in larger studies. Disclosures All Authors: No reported disclosures

scholarly journals Child deaths at National District Hospital, Free State: one a month is better than one a week

2017 ◽  
Vol 59 (3) ◽  
pp. 36
Author(s):  
H Brits
Keyword(s):  
Child Mortality ◽  
District Hospital ◽  
Integrated Management ◽  
Scale Up ◽  
Hiv Care ◽  
Treatment And Prevention ◽  
Child Deaths ◽  
Before And After ◽  
Development Goals ◽  
Mdg 4

Background: The United Nations set a two-thirds reduction in child mortality between 1990 and 2015 in the Millennium Development Goals (MDGs) of 2000. The National Department of Health (NDoH) introduced strategies to achieve these MDGs, which included new vaccines, better HIV care and training of healthcare workers. This study investigated whether the strategies implemented by the NDoH decreased child mortality (MDG 4) at National District Hospital (NDH). Method: A retrospective file review was done on all children that died in NDH from 2008 to 2015. Data were collected from patient files and ChildPIP data forms. Deaths before and after the implementation of the strategies were compared. Results: A total of 209 children died during the study period. The mortality rate decreased from 47 per thousand admissions and stabilised at 15 per thousand admissions for the past five years. Deaths due to acute gastroenteritis decreased from 67% of the total to less than 40%. Pneumonia as the main cause of death decreased from 44 during the 2008–2010 period to 19 during the 2011–2015 period. More than 90% of the children who died were malnourished. There was no statistically significant improvement in the malnutrition rates during the study periods (p = 0.85). Conclusion: Child deaths decreased from one a week to one a month at NDH. Strategies to meet the MDG 4 targets, like the introduction of the Rotavirus and Pneumococcal vaccine, the scale-up of anti-retroviral treatment and Prevention of Mother to Child transmission of HIV and better Integrated Management of Childhood Illness training all contributed to the better outcome. (Full text of the research articles are available online at www.medpharm.tandfonline.com/ojfp) S Afr Fam Pract 2017; DOI: 10.1080/20786190.2017.1317991

scholarly journals Physiotherapists` knowledge of the transmission and prevention of communicable diseases

2003 ◽  
Vol 59 (1) ◽  
Author(s):  
L. Grobler ◽  
N. Kleynhans ◽  
A. Lubbe ◽  
T. Smit ◽  
C. Retief ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Hepatitis B ◽  
Hepatitis A ◽  
Communicable Diseases ◽  
Free State ◽  
Effective Protection ◽  
Adequate Knowledge ◽  
Preventative Measures ◽  
Better Than ◽  
Hiv Aids

With the world-wide increase of communicable diseases, adequate knowledge by health professionals of the transmission and prevention of these diseases is essential to ensure effective protection.  The aim of this study was to determine whether practising physiotherapists’ knowledge of the transmission and prevention of tuberculosis, hepatitis A, hepatitis B, hepatitis C and HIV/AIDS was adequate to ensure effective protection.A descriptive study was conducted.  One hundred and forty six practising physiotherapists in the Free State received questionnaires on which they had to indicate the relevant transmission and preventative measures for each disease. One hundred and three (70.5%) questionnaires were returned.  Points were allocated for the knowledge of transmission and preventative measures.  The medians with respect to transmission were: tuberculosis 83%, hepatitis A 58%, hepatitis B 67%, hepatitis C 75% and HIV/AIDS 92%.  The medians with respect to preventative measures were: tuberculosis 57%, hepatitis A 58%, hepatitis B 77%, hepatitis C 67% and HIV/AIDS 71%.  The knowledge of transmission was better than the knowledge of preventative measures.  An increase in the knowledge of practising physiotherapists in the Free State is needed to ensure their maximal protection against communicable diseases.

Time and Latitude in South Africa

1972 ◽  
Vol 1 ◽  
pp. 27-38
Author(s):  
J. Hers
Keyword(s):  
South Africa ◽  
Cape Town ◽  
Astronomical Observations ◽  
Royal Observatory ◽  
The Republic ◽  
Astronomical Determination ◽  
Limited Accuracy ◽  
Better Than

In South Africa the modern outlook towards time may be said to have started in 1948. Both the two major observatories, The Royal Observatory in Cape Town and the Union Observatory (now known as the Republic Observatory) in Johannesburg had, of course, been involved in the astronomical determination of time almost from their inception, and the Johannesburg Observatory has been responsible for the official time of South Africa since 1908. However the pendulum clocks then in use could not be relied on to provide an accuracy better than about 1/10 second, which was of the same order as that of the astronomical observations. It is doubtful if much use was made of even this limited accuracy outside the two observatories, and although there may – occasionally have been a demand for more accurate time, it was certainly not voiced.

Localization of immunolabels by electron microscopy and image averaging

1983 ◽  
Vol 41 ◽  
pp. 282-283
Author(s):  
J. Frank ◽  
P.-Y. Sizaret ◽  
A. Verschoor ◽  
J. Lamy
Keyword(s):  
Electron Microscopy ◽  
Single Particle ◽  
Attachment Site ◽  
Uranyl Acetate ◽  
Limulus Polyphemus ◽  
Resolution Limit ◽  
Electron Microscopic ◽  
Image Averaging ◽  
Top View ◽  
Better Than

The accuracy with which the attachment site of immunolabels bound to macromolecules may be localized in electron microscopic images can be considerably improved by using single particle averaging. The example studied in this work showed that the accuracy may be better than the resolution limit imposed by negative staining (∽2nm).The structure used for this demonstration was a halfmolecule of Limulus polyphemus (LP) hemocyanin, consisting of 24 subunits grouped into four hexamers. The top view of this structure was previously studied by image averaging and correspondence analysis. It was found to vary according to the flip or flop position of the molecule, and to the stain imbalance between diagonally opposed hexamers (“rocking effect”). These findings have recently been incorporated into a model of the full 8 × 6 molecule.LP hemocyanin contains eight different polypeptides, and antibodies specific for one, LP II, were used. Uranyl acetate was used as stain. A total of 58 molecule images (29 unlabelled, 29 labelled with antl-LPII Fab) showing the top view were digitized in the microdensitometer with a sampling distance of 50μ corresponding to 6.25nm.

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