Age, Sex, and Performance Influence the Visuospatial Working Memory Network in Childhood

2013 ◽  
Vol 38 (4) ◽  
pp. 236-255 ◽  
Author(s):  
Megan Spencer-Smith ◽  
Barbara Catherine Ritter ◽  
Ines Mürner-Lavanchy ◽  
Marwan El-Koussy ◽  
Maja Steinlin ◽  
...  
Keyword(s):  
Working Memory ◽  
Visuospatial Working Memory ◽  
Memory Network ◽  
And Performance

scholarly journals The Fear to Move in a Crowded Environment. Poor Spatial Memory Related to Agoraphobic Disorder

2021 ◽  
Vol 11 (6) ◽  
pp. 796
Author(s):  
Micaela Maria Zucchelli ◽  
Laura Piccardi ◽  
Raffaella Nori
Keyword(s):  
Working Memory ◽  
Spatial Information ◽  
Theoretical Background ◽  
Exploratory Activity ◽  
Visuospatial Working Memory ◽  
Spatial Tasks ◽  
And Performance ◽  
The Relationship ◽  
Crowded Environment ◽  
Active Processing

Individuals with agoraphobia exhibit impaired exploratory activity when navigating unfamiliar environments. However, no studies have investigated the contribution of visuospatial working memory (VSWM) in these individuals’ ability to acquire and process spatial information while considering the use of egocentric and allocentric coordinates or environments with or without people. A total of 106 individuals (53 with agoraphobia and 53 controls) navigated in a virtual square to acquire spatial information that included the recognition of landmarks and the relationship between landmarks and themselves (egocentric coordinates) and independent of themselves (allocentric coordinates). Half of the participants in both groups navigated in a square without people, and half navigated in a crowded square. They completed a VSWM test in addition to tasks measuring landmark recognition and egocentric and allocentric judgements concerning the explored square. The results showed that individuals with agoraphobia had reduced working memory only when active processing of spatial elements was required, suggesting that they exhibit spatial difficulties particularly in complex spatial tasks requiring them to process information simultaneously. Specifically, VSWM deficits mediated the relationship between agoraphobia and performance in the allocentric judgements. The results are discussed considering the theoretical background of agoraphobia in order to provide useful elements for the early diagnosis of this disorder.

Co-ordination within and between verbal and visuospatial working memory: network modulation and anterior frontal recruitment

NeuroImage ◽  
2003 ◽  
Vol 20 (2) ◽  
pp. 1298-1308 ◽  
Author(s):  
A Kübler ◽  
K Murphy ◽  
J Kaufman ◽  
E.A Stein ◽  
H Garavan
Keyword(s):  
Working Memory ◽  
Visuospatial Working Memory ◽  
Memory Network

166. Expression of GABA Neuron Markers across the Cortical Visuospatial Working Memory Network in Schizophrenia

2017 ◽  
Vol 81 (10) ◽  
pp. S69
Author(s):  
Makoto Tsubomoto ◽  
Rika Kawabata ◽  
Yoshio Minabe ◽  
Takanori Hashimoto ◽  
David Lewis
Keyword(s):  
Working Memory ◽  
Visuospatial Working Memory ◽  
Gaba Neuron ◽  
Memory Network

scholarly journals The association of visuospatial working memory with dysthymic disorder in pre-pubertal children

2009 ◽  
Vol 40 (2) ◽  
pp. 253-261 ◽  
Author(s):  
T. Franklin ◽  
A. Lee ◽  
N. Hall ◽  
S. Hetrick ◽  
J. Ong ◽  
...  
Keyword(s):  
Working Memory ◽  
Cross Sectional Study ◽  
Dysthymic Disorder ◽  
Control Group ◽  
Visuospatial Working Memory ◽  
Cross Sectional ◽  
Spatial Span ◽  
Matched Healthy Control ◽  
Healthy Control ◽  
And Performance

BackgroundVisuospatial working memory (VSWM) deficits have not been investigated specifically in children with dysthymic disorder (DD), although they are associated with impairments in attention that commonly occur in DD. This study investigates VSWM impairment in children with DD.MethodA cross-sectional study of VSWM in 6- to 12-year-old children with medication-naive DD (n=26) compared to an age-, gender- and ‘performance IQ’ (PIQ)-matched healthy control group (n=28) was completed.ResultsThe DD group demonstrated impairment in VSWM, including impairment in the spatial span and strategy components of VSWM. Furthermore, the VSWM impairment remained after controlling for spatial span. Inattentive symptoms were significantly associated with the VSWM impairment.ConclusionsThis study of children with DD found deficits in performance on VSWM tasks, suggesting that fronto-striatal–parietal neural networks that underlie processes of attention and the executive component of VSWM are dysfunctional in children with DD. These findings further our understanding of DD and suggest more specific interventions that might improve functioning.

T202. Expression of Stau2-Regulated Transcripts Across the Cortical Visuospatial Working Memory Network in Schizophrenia

2018 ◽  
Vol 83 (9) ◽  
pp. S206-S207
Author(s):  
Sohei Kimoto ◽  
Takanori Hashimoto ◽  
Makoto Tsubomoto ◽  
Yasunari Yamaguchi ◽  
Rika Kawabata ◽  
...  
Keyword(s):  
Working Memory ◽  
Visuospatial Working Memory ◽  
Memory Network

scholarly journals Altered Gradients of Glutamate and Gamma-Aminobutyric Acid Transcripts in the Cortical Visuospatial Working Memory Network in Schizophrenia

2018 ◽  
Vol 83 (8) ◽  
pp. 670-679 ◽  
Author(s):  
Gil D. Hoftman ◽  
Samuel J. Dienel ◽  
Holly H. Bazmi ◽  
Yun Zhang ◽  
Kehui Chen ◽  
...  
Keyword(s):  
Working Memory ◽  
Aminobutyric Acid ◽  
Gamma Aminobutyric Acid ◽  
Visuospatial Working Memory ◽  
Memory Network

T50. Laminar and Cellular Developmental Trajectories of GABA Transcripts in Cortical Regions of the Visuospatial Working Memory Network in Monkeys

2019 ◽  
Vol 85 (10) ◽  
pp. S148
Author(s):  
Gil Hoftman ◽  
Jennifer Burns ◽  
Elizabeth Profozich ◽  
H. Holly Bazmi ◽  
Kenneth Fish ◽  
...  
Keyword(s):  
Working Memory ◽  
Developmental Trajectories ◽  
Visuospatial Working Memory ◽  
Memory Network ◽  
Cortical Regions

Stronger Synaptic Connectivity as a Mechanism behind Development of Working Memory-related Brain Activity during Childhood

2007 ◽  
Vol 19 (5) ◽  
pp. 750-760 ◽  
Author(s):  
Fredrik Edin ◽  
Julian Macoveanu ◽  
Pernille Olesen ◽  
Jesper Tegnér ◽  
Torkel Klingberg
Keyword(s):  
Working Memory ◽  
Developmental Process ◽  
Brain Activity ◽  
Working Memory Capacity ◽  
Developmental Changes ◽  
Synaptic Connectivity ◽  
Visuospatial Working Memory ◽  
Functional Magnetic Resonance ◽  
And Performance ◽  
Synaptic Pruning

The cellular maturational processes behind cognitive development during childhood, including the development of working memory capacity, are still unknown. By using the most standard computational model of visuospatial working memory, we investigated the consequences of cellular maturational processes, including myelination, synaptic strengthening, and synaptic pruning, on working memory-related brain activity and performance. We implemented five structural developmental changes occurring as a result of the cellular maturational processes in the biophysically based computational network model. The developmental changes in memory activity predicted from the simulations of the model were then compared to brain activity measured with functional magnetic resonance imaging in children and adults. We found that networks with stronger fronto-parietal synaptic connectivity between cells coding for similar stimuli, but not those with faster conduction, stronger connectivity within a region, or increased coding specificity, predict measured developmental increases in both working memory-related brain activity and in correlations of activity between regions. Stronger fronto-parietal synaptic connectivity between cells coding for similar stimuli was thus the only developmental process that accounted for the observed changes in brain activity associated with development of working memory during childhood.

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