scholarly journals THE ASSAY OF HYPERTENSIN FROM THE ARTERIAL BLOOD OF NORMOTENSIVE AND HYPERTENSIVE HUMAN BEINGS

1952 ◽  
Vol 95 (6) ◽  
pp. 523-529 ◽  
Author(s):  
Joseph R. Kahn ◽  
Leonard T. Skeggs ◽  
Norman P. Shumway ◽  
Paul E. Wisenbaugh
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Normal Blood ◽  
Moderate Degree ◽  
Human Beings ◽  
Normal Blood Pressure ◽  
Arterial Blood ◽  
The Mean ◽  
Mean Concentration ◽  
Benign Group

Hypertensin has been assayed in the blood of patients with normal blood pressure and in those with essential hypertension in both the benign and malignant phases. 250 ml. samples of arterial blood were obtained, chemically purified, and concentrated to a volume of 1 ml. These extracts were then assayed in anesthetized rats. The concentrations of hypertensin in the blood of patients with the malignant phase of essential hypertension were found to be greatly increased. The concentrations of hypertensin found in patients with benign hypertension had a moderate degree of overlapping with those found in the normotensive group, but the mean concentration of hypertensin in the former group was twice that of the controls. Although these results are statistically significant, the amounts of hypertensin recovered in the benign group are so small that no conclusions can be drawn as to its effectiveness in producing vasoconstriction in these patients.

Sex-dependent relation between ionized calcium in serum and blood pressure.

1984 ◽  
Vol 30 (1) ◽  
pp. 116-118 ◽  
Author(s):  
N Fogh-Andersen ◽  
L Hedegaard ◽  
J Thode ◽  
O Siggaard-Andersen
Keyword(s):  
Blood Pressure ◽  
Ionized Calcium ◽  
Thiazide Diuretics ◽  
Normal Blood Pressure ◽  
Arterial Blood ◽  
Dependent Relation ◽  
The Mean ◽  
Adrenergic Blocking ◽  
Beta Adrenergic Blocking Agents ◽  
Mean Concentration

Abstract In an epidemiological study of 977 45-year-olds, both the mean concentration of ionized calcium in serum, [Ca2+]7.4, and arterial blood pressure were higher in men than in women. Among the men, there was a weak positive correlation between [Ca2+]7.4 and the systolic blood pressure, but no other significant correlation was found within each separate sex. Postmenopausal women had slightly increased [Ca2+]7.4 but normal blood pressure. Patients taking thiazide diuretics or beta-adrenergic blocking agents had normal [Ca2+]7.4.

scholarly journals A longitudinal analysis of the progression from normal blood pressure to stage 2 hypertension: A 12-year Korean cohort

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Eun Sun Yu ◽  
Kwan Hong ◽  
Byung Chul Chun
Keyword(s):  
Blood Pressure ◽  
Health Insurance ◽  
American Heart Association ◽  
American Heart ◽  
Heart Association ◽  
Normal Blood ◽  
Normal Blood Pressure ◽  
The Mean ◽  
Stage 1

Abstract Background The study aimed to estimate the incidence of and period of progression to stage 2 hypertension from normal blood pressure. Methods We selected a total of 21,172 normotensive individuals between 2003 and 2004 from the National Health Insurance Service-Health Screening and followed them up until 2015. The criteria for blood pressure were based on the American College of Cardiology/American Heart Association 2017 guideline (normal BP: SBP < 120 and DBP < 80 mmHg, elevated BP: SBP 120–129 and DBP < 80 mmHg, stage 1 hypertension: SBP 130–139 or DBP 80–89 mmHg, stage 2 hypertension: SBP ≥140 or DBP ≥ 90 mmHg). We classified the participants into four courses (Course A: normal BP → elevated BP → stage 1 hypertension→ stage 2 hypertension, Course B: normal BP → elevated BP → stage 2 hypertension, Course C: normal BP → stage 1 hypertension → stage 2 hypertension, Course D: normal BP → stage 2 hypertension) according to their progression from normal blood pressure to stage 2 hypertension. Results During the median 12.23 years of follow-up period, 52.8% (n= 11,168) and 23.6% (n=5004) of the participants had stage 1 and stage 2 hypertension, respectively. In particular, over 60 years old had a 2.8-fold higher incidence of stage 2 hypertension than 40–49 years old. After the follow-up period, 77.5% (n=3879) of participants with stage 2 hypertension were found to be course C (n= 2378) and D (n=1501). After the follow-up period, 77.5% (n=3879) of participants with stage 2 hypertension were found to be course C (n= 2378) and D (n=1501). The mean years of progression from normal blood pressure to stage 2 hypertension were 8.7±2.6 years (course A), 6.1±2.9 years (course B), 7.5±2.8 years (course C) and 3.2±2.0 years, respectively. Conclusions This study found that the incidence of hypertension is associated with the progression at each stage. We suggest that the strategies necessary to prevent progression to stage 2 hypertension need to be set differently for each target course.

Abnormalities of peripheral venous tone in women with pregnancy-induced hypertension

1986 ◽  
Vol 70 (2) ◽  
pp. 155-157 ◽  
Author(s):  
Karen Stainer ◽  
Rachel Morrison ◽  
C. Pickles ◽  
A. J. Cowley
Keyword(s):  
Blood Pressure ◽  
Pregnant Women ◽  
Inverse Correlation ◽  
The Other ◽  
Normal Blood ◽  
Pregnancy Induced Hypertension ◽  
Normal Blood Pressure ◽  
Venous Tone ◽  
Arterial Blood ◽  
Induced Hypertension

1. Forearm venous tone was measured in two groups of pregnant women: one group with pregnancy-induced hypertension and the other group with normal blood pressure. 2. The women with pregnancy-induced hypertension were venoconstricted in the forearm (P < 0.01) compared with the pregnant women with normal blood pressure. However, there was no difference in venous tone between the women with pregnancy-induced hypertension and nonpregnant women. 3. There was an inverse correlation between mean arterial blood pressure and forearm venous tone (r = −0.581, P < 0.001) for all the pregnant women studied. Further evaluation of peripheral venous tone may provide valuable information about the pathophysiology and treatment of women with pregnancy-induced hypertension.

Water, Cations, and Norepinephrine Content of Cardiovascular Tissues of Unilaterally Nephrectomized Dogs Treated with Deoxycorticosterone and NaCl

1975 ◽  
Vol 53 (5) ◽  
pp. 866-872 ◽  
Author(s):  
George Constantopoulos ◽  
Jacques Genest ◽  
Miyako Kusumoto ◽  
José-Manuel Rojo-Ortega
Keyword(s):  
Blood Pressure ◽  
Mesenteric Arteries ◽  
Normal Blood Pressure ◽  
Sodium Potassium ◽  
Arterial Blood ◽  
Cardiovascular Tissues ◽  
Norepinephrine Content ◽  
The Mean ◽  
Potassium Magnesium ◽  
Drinking Solution

Deoxycorticosterone pivalate (2.5 mg/kg) given intramuscularly on four occasions 10–15 days apart over a period of 45 days to unilaterally nephrectomized adult male mongrel dogs, receiving as drinking solution 0.9% NaCl in 5% dextrose, resulted in an average sustained rise in the mean arterial blood pressure of 30 mm Hg (1 mm Hg = 133 N/m2) in 60% of the animals. Hypertensive dogs had in their arterial tissues generally more sodium, potassium, magnesium, and calcium than the similarly treated but non-hypertensive dogs, but compared to the tissues of operated untreated or unoperated normotensive dogs, only sodium and calcium were significantly higher. The dogs who were similarly treated but did not develop hypertension had in their arterial tissues less sodium, potassium, and magnesium than operated untreated or unoperated normotensive dogs. Norepinephrine content in the branches of mesenteric arteries of all deoxycorticosterone- and NaCl-treated animals, irrespective of their blood pressure, was significantly lower, and in the myocardium significantly higher, than either the unoperated normotensive or operated but not further treated dogs. It is concluded, therefore, that in deoxycorticosterone + NaCl treatment the dogs which developed hypertension had more arterial sodium, potassium, magnesium, and calcium than those who were similarly treated but remained within the limits of normal blood pressure, and that there was no difference between hypertensive and non-hypertensive dogs in regard to their cardiovascular norepinephrine content.

THE FLUSH METHOD FOR DETERMINING BLOOD PRESSURES IN INFANTS

PEDIATRICS ◽  
1958 ◽  
Vol 21 (6) ◽  
pp. 950-957
Author(s):  
Arthur J. Moss ◽  
Wilbert Liebling ◽  
Forrest H. Adams
Keyword(s):  
Blood Pressure ◽  
Body Weight ◽  
Normal Blood ◽  
First Year ◽  
Pressure Measurements ◽  
Normal Blood Pressure ◽  
Chronic Infections ◽  
Arithmetic Means ◽  
Blood Pressures ◽  
The Mean

Observations were made on 551 Caucasian infants from 1 day to 1 year of age. All subjects had normal cardiovascular status and were free from acute or chronic infections. A total of 1,712 measurements of blood pressure were obtained by the flush technique. It is known that measurements made using the flush technique approximate the mean rather than the systolic blood pressure. The values obtained were analyzed in relation to sex, age and body weight. No correlation is found between sex and blood pressure or between body weight within a given monthly age category and blood pressure. Measurements of blood pressure show a pronounced and highly significance rise following the first week of life. During the first 9 months of life the readings are somewhat higher at the wrist than at the ankle. Thereafter, the converse is true. The significance of these findings is discussed. Arithmetic means and the range of normal blood pressure are presented. Exclusive of the first week of life, the range of normal blood pressure during the first year is from 51 to 93 mm Hg for the upper extremity and from 44 to 92 mm Hg for the lower extremity.

scholarly journals NORMAL BLOOD PRESSURE IN OFFSPRING OF PATIENTS WITH ESSENTIAL HYPERTENSION

1977 ◽  
Vol 11 (4) ◽  
pp. 437-437
Author(s):  
Bernard S Kaplan ◽  
Hyman Fox ◽  
Ernest Seidman ◽  
Keith N Drummond
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Normal Blood ◽  
Normal Blood Pressure

scholarly journals Oat Consumption Does Not Affect Resting Casual and Ambulatory 24-h Arterial Blood Pressure in Men with High-Normal Blood Pressure to Stage I Hypertension

2002 ◽  
Vol 132 (3) ◽  
pp. 394-398 ◽  
Author(s):  
Brenda M. Davy ◽  
Christopher L. Melby ◽  
Stacy D. Beske ◽  
Richard C. Ho ◽  
Linda R. Davrath ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Arterial Blood Pressure ◽  
Stage I ◽  
Normal Blood ◽  
Normal Blood Pressure ◽  
Arterial Blood
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