scholarly journals Risk of Fatal Adverse Events after H1N1 Influenza Vaccine: Limitations of Passive Surveillance Data

2010 ◽  
Vol 51 (7) ◽  
pp. 871-872 ◽  
Author(s):  
Michael M. McNeil ◽  
Karen R. Broder ◽  
Claudia Vellozzi ◽  
Frank DeStefano
Keyword(s):  
Adverse Events ◽  
Influenza Vaccine ◽  
H1n1 Influenza ◽  
Surveillance Data ◽  
Passive Surveillance ◽  
Fatal Adverse Events

scholarly journals Gastrointestinal Events in High-Dose vs Standard-Dose Influenza Vaccine Recipients

2018 ◽  
Vol 5 (6) ◽  
Author(s):  
H Keipp Talbot ◽  
Andrew J Dunning ◽  
Corwin A Robertson ◽  
Victoria A Landolfi ◽  
David P Greenberg ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Adverse Events ◽  
Influenza Vaccine ◽  
Randomized Clinical Trial ◽  
Standard Dose ◽  
High Dose ◽  
Passive Surveillance ◽  
Prospective Randomized Clinical Trial ◽  
Gastrointestinal Events ◽  
Gastrointestinal Adverse Events

Abstract Passive surveillance data had signaled the possibility of gastrointestinal adverse events occurring after the administration of high-dose inactivated influenza vaccine (IIV-HD). However, in a large, prospective randomized clinical trial, rates of serious gastrointestinal events were no greater among IIV-HD recipients than among those who received a standard-dose influenza vaccine.

scholarly journals Risk of Fatal Adverse Events after H1N1 Influenza Vaccination

2010 ◽  
Vol 50 (11) ◽  
pp. 1548-1549 ◽  
Author(s):  
Haruka Nakada ◽  
Hiroto Narimatsu ◽  
Masaharu Tsubokura ◽  
Naoko Murashige ◽  
Tomoko Matsumura ◽  
...  
Keyword(s):  
Adverse Events ◽  
Influenza Vaccination ◽  
H1n1 Influenza ◽  
Fatal Adverse Events

Monovalent H1N1 influenza vaccine safety in pregnant women, risks for acute adverse events

Vaccine ◽  
2014 ◽  
Vol 32 (39) ◽  
pp. 4985-4992 ◽  
Author(s):  
James D. Nordin ◽  
Elyse Olshen Kharbanda ◽  
Gabriela Vazquez-Benitez ◽  
Heather Lipkind ◽  
Grace M. Lee ◽  
...  
Keyword(s):  
Adverse Events ◽  
Influenza Vaccine ◽  
Pregnant Women ◽  
Vaccine Safety ◽  
H1n1 Influenza

scholarly journals Strengths and limitations of assessing influenza vaccine effectiveness using routinely collected, passive surveillance data in Ontario, Canada, 2007 to 2012: balancing efficiency versus quality

2015 ◽  
Vol 20 (16) ◽  
Author(s):  
R D Savage ◽  
A L Winter ◽  
L C Rosella ◽  
R Olsha ◽  
J B Gubbay ◽  
...  
Keyword(s):  
Influenza Vaccine ◽  
Vaccine Effectiveness ◽  
Surveillance Data ◽  
Passive Surveillance ◽  
Binary File ◽  
Balancing Efficiency

Binary file ES_Abstracts_Final_ECDC.txt matches

scholarly journals Correlates of 2009 H1N1 influenza vaccine acceptability among parents and their adolescent children

2011 ◽  
Vol 26 (5) ◽  
pp. 751-760 ◽  
Author(s):  
J. E. Painter ◽  
L. M. Gargano ◽  
J. M. Sales ◽  
C. Morfaw ◽  
L. M. Jones ◽  
...  
Keyword(s):  
Influenza Vaccine ◽  
H1n1 Influenza ◽  
Vaccine Acceptability ◽  
2009 H1n1

Safety of the Pandemic H1N1 Influenza Vaccine Among Pregnant U.S. Military Women and Their Newborns

2013 ◽  
Vol 121 (3) ◽  
pp. 511-518 ◽  
Author(s):  
Ava Marie S. Conlin ◽  
Anna T. Bukowinski ◽  
Carter J. Sevick ◽  
Connie DeScisciolo ◽  
Nancy F. Crum-Cianflone
Keyword(s):  
Influenza Vaccine ◽  
H1n1 Influenza ◽  
Military Women ◽  
Pandemic H1n1 ◽  
Pandemic H1n1 Influenza

scholarly journals Predictors of adverse prognosis in patients with infective endocarditis in a surgical referral center

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
V Scheggi ◽  
I Olivotto ◽  
N Ceschia ◽  
I Merilli ◽  
V Andrei ◽  
...  
Keyword(s):  
Renal Failure ◽  
Infective Endocarditis ◽  
Adverse Events ◽  
Ejection Fraction ◽  
Relapse Rate ◽  
Left Ventricular Ejection ◽  
All Cause Mortality ◽  
Fatal Adverse Events

Abstract Background Despite optimal medical and surgical treatment, mortality in infective endocarditis (IE) remains high. Aim of this study was to identify predictors of long term mortality for any cause, adverse event rate, relapse rate and valvular dysfunction at follow-up, in a high-volume surgical center. Methods We retrospectively analyzed 358 consecutive patients (127 women) admitted to our department with definite diagnosis of IE not device-related. IE occurred on native valves in 224 patients (63%); the infection involved the aortic valve in 192 (54%), mitral valve in 139 (39%) and tricuspid valve in 26 (7%). Overall 285 (80%) patients underwent surgery and 73 (20%) were treated conservatively, 38 due to absence of surgical indication and 35 due to refusal or prohibitive surgical risk. Long-term follow-up was obtained by structured telephone interviews. Primary endpoints were all-cause mortality, freedom from recurrent endocarditis, postoperative incidence of major adverse events (hospitalization for any cause, pace-maker implantation, new onset of atrial fibrillation, sternal dehiscence), worsening of left ventricular ejection fraction (LVEF) and valvular dysfunction. Results Mean age was 65 years (SD 15.2). Mean vegetation length was 8.9 mm (SD 7.6). Endocarditis was left-sided in 332 (93%). Average follow-up was 6 months. At univariable analysis, mortality was associated with female gender (p=0.031), age (p<0.001), higher EuroSCORE 2 (p<0.001), chronic renal failure (p<0.001), diabetes (p=0.002), brain embolism on presentation (p=0.05), double valve infection (p=0.008), low ejection fraction (p<0.001), paravalvular extension (p=0.031), prosthetic infection (p=0.018), exclusion from surgery if indicated (p<0.001), high procalcitonin levels (p=0.035); factors associated with a significantly lower mortality were streptococcal infection (p=0.04; OR 0.34) and early surgery (p=0.009, OR 0.55). At multivariable analysis independent predictors of all-cause mortality were lower EF, EuroSCORE2, procalcitonin levels and diabetes. Non-fatal adverse events were associated with renal failure (p 0.035, OR 2.8). Relapse rate was associated with S aureus infection (p=0.005, OR 3.8), right-sided endocarditis (p<0.001, OR 6.7) and drug abuse (p<0.001, OR 9.4). Conclusions The present study shows that low EF, EuroSCORE2, procalcitonin levels and diabetes are independent predictors of death in patients with IE. Non-fatal adverse events are more frequent in patients with renal failure. Relapse rate is higher in drug abusers. These informations may help personalize follow-up strategies after acute admission for IE. Funding Acknowledgement Type of funding source: None

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