A logical approach to optimize the nanostructured lipid carrier system of irinotecan: efficient hybrid design methodology

2012 ◽  
Vol 24 (1) ◽  
pp. 015104 ◽  
Author(s):  
Lalit Mohan Negi ◽  
Manu Jaggi ◽  
Sushama Talegaonkar
Keyword(s):  
Design Methodology ◽  
Hybrid Design ◽  
Nanostructured Lipid Carrier ◽  
Carrier System ◽  
Logical Approach

Formulation, Optimization and Evaluation of Nanostructured Lipid Carrier System of Acyclovir for Topical Delivery

2014 ◽  
Vol 8 (4) ◽  
pp. 235-247 ◽  
Author(s):  
M. A. Iqbal ◽  
Shadab Md ◽  
Gulam Mustafa ◽  
Manish Kumar ◽  
Sanjula Baboota ◽  
...  
Keyword(s):  
Topical Delivery ◽  
Nanostructured Lipid Carrier ◽  
Carrier System ◽  
Formulation Optimization

Hybrid (Symbolic-Numerical) Optimization in Mechanism Design for the Elimination of Redundant Constraints

1991 ◽  
Vol 113 (2) ◽  
pp. 110-123 ◽  
Author(s):  
D. A. Hoeltzel ◽  
Wei-Hua Chieng
Keyword(s):  
Design Optimization ◽  
Numerical Optimization ◽  
Design Methodology ◽  
Degrees Of Freedom ◽  
Systematic Approach ◽  
Hybrid Design ◽  
New Approach ◽  
Symbolic Reasoning ◽  
Algorithmic Analysis ◽  
Programming Algorithms

Hybrid optimization, a new approach to design optimization employing both symbolic reasoning and algorithmic analysis, has been applied to the design of kinematic pairs in mechanisms. This hybrid design methodology provides a three-step systematic approach for (1) combining the degrees-of-freedom found in simple, lower kinematic pairs to obtain more complex but robust higher pairs, (2) judging inappropriately assigned joints for the elimination of redundant kinematic constraints and harmful mobilities, and (3) assisting nonexpert designers in applying nonlinear programming algorithms for detailed numerical design optimization of kinematic pairs. An example taken from the design of a spatial mechanism, specifically a universal joint, is presented and serves to demonstrate the utility of this procedure for detailed hybrid design optimization of kinematic pairs in mechanisms.

scholarly journals Nanostructured lipid carrier system for topical delivery of terbinafine hydrochloride

2015 ◽  
Vol 53 (2) ◽  
pp. 147-159 ◽  
Author(s):  
Bharti Gaba ◽  
Mohammad Fazil ◽  
Saba Khan ◽  
Asgar Ali ◽  
Sanjula Baboota ◽  
...  
Keyword(s):  
Topical Delivery ◽  
Nanostructured Lipid Carrier ◽  
Carrier System ◽  
Terbinafine Hydrochloride
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