Accelerometry: providing an integrated, practical method for long-term, ambulatory monitoring of human movement

2004 ◽  
Vol 25 (2) ◽  
pp. R1-R20 ◽  
Author(s):  
Merryn J Mathie ◽  
Adelle C F Coster ◽  
Nigel H Lovell ◽  
Branko G Celler
2013 ◽  
Vol 36 (9) ◽  
pp. 795-798 ◽  
Author(s):  
Paolo Giorgini ◽  
Rinaldo Striuli ◽  
Marco Petrarca ◽  
Luisa Petrazzi ◽  
Paolo Pasqualetti ◽  
...  

Measurement ◽  
2020 ◽  
Vol 157 ◽  
pp. 107671
Author(s):  
Chihiro Kamio ◽  
Tatsuhito Aihara ◽  
Gaku Minorikawa

Blood ◽  
1970 ◽  
Vol 36 (5) ◽  
pp. 623-627 ◽  
Author(s):  
J. HIRSH ◽  
J. F. CADE ◽  
A. S. GALLUS

Abstract The safest and most practical method of administering long-term anticoagulants in pregnancy is uncertain because treatment of the mother with vitamin K antagonists may be complicated by hemorrhage in the fetus. The effects on the fetus of giving coumadin in pregnancy was evaluated in rabbits. When coumadin was given from early pregnancy until term, all of the fetuses were stillborn with widespread hemorrhages. However, the fetuses were born alive and without hemorrhage when (1) coumadin was stopped 4-5 days before delivery, at which time the level of coagulation factors had almost returned to normal and (2) when delivery was performed by cesarean section at a time when the fetal coagulation defect was severe. It is suggested that the risk of fetal hemorrhage is high only when fetuses with a severe coagulation defect are exposed to the trauma of delivery.


2011 ◽  
Vol 4 ◽  
pp. 4193-4198 ◽  
Author(s):  
Régis Farret ◽  
Philippe Gombert ◽  
Franz Lahaie ◽  
Auxane Cherkaoui ◽  
Stéphane Lafortune ◽  
...  

2013 ◽  
Vol 13 (02) ◽  
pp. 1350041 ◽  
Author(s):  
MITSURU YONEYAMA ◽  
HIROSHI MITOMA ◽  
YASUYUKI OKUMA

Accelerometry-based motion analysis is widely recognized as a promising tool in health care and medical settings since it is unobtrusive, inexpensive, and capable of providing useful information on human movement disorders. Patients suffering from neurological diseases such as Parkinson's disease (PD) often exhibit a combination of multiple motion symptoms during everyday activities. Thus, there is a need in clinical practice to capture as many types of abnormal movements as possible with minimal instrumentation that does not interfere with the subject's usual behavioral patterns. This paper presents the prospect of total health monitoring with a single accelerometer-based technique. The behavior of a PD patient was continuously recorded for a period of 36 h using a portable device with a triaxial accelerometer worn on the waist. Data were analyzed by newly developed computer programs to extract relevant movement parameters that might underlie pathological motor performance. We found that the state of the disease could be quantified in terms of distinctive aspects such as gait force, synchronization between both legs, and falls during diurnal walking, and turnover and respiration during nocturnal sleep. Our method may be a useful and practical tool that enables refined clinical assessment of the overall health status of patients with motion disorders.


2022 ◽  
Author(s):  
Furong Ju ◽  
Wenling Jian ◽  
Yaning Han ◽  
Tianwen Huang ◽  
Jin Ke ◽  
...  

The spinal cord is critical to integrating peripheral information under sensory-guided motor behaviors in health and disease. However, the cellular activity underlie spinal cord function in freely behaving animals is not clear. Here, we developed a new method for imaging the spinal cord at cellular and subcellular resolution over weeks under naturalistic conditions. The method involves an improved surgery to reduce spinal movement, and the installation of a miniaturized two-photon microscope to obtain high-resolution imaging in moving mice. In vivo calcium imaging demonstrated that dorsal horn neurons show a sensorimotor program-dependent synchronization and heterogeneity under distinct cutaneous stimuli in behaving mice. The long-term imaging of sensory neurons revealed that in the spinal cord, healthy mice demonstrated stereotyped responses. However, in a neuropathic pain model, plasticity changes and neuronal sensitization were observed. We provide a practical method to study the function of spinal cord on sensory perception and disorders in freely behaving mice.


2021 ◽  
Author(s):  
Steven M Peterson ◽  
Satpreet H Singh ◽  
Benjamin Dichter ◽  
Michael Scheid ◽  
Rajesh P. N. Rao ◽  
...  

Understanding the neural basis of human movement in naturalistic scenarios is critical for expanding neuroscience research beyond constrained laboratory paradigms. Here, we describe our Annotated Joints in Long-term Electrocorticography for 12 human participants (AJILE12) dataset, the largest human neurobehavioral dataset that is publicly available; the dataset was recorded opportunistically during passive clinical epilepsy monitoring. AJILE12 includes synchronized intracranial neural recordings and upper body pose trajectories across 55 semi-continuous days of naturalistic movements, along with relevant metadata, including thousands of wrist movement events and annotated behavioral states. Neural recordings are available at 500 Hz from at least 64 electrodes per participant, for a total of 1280 hours. Pose trajectories at 9 upper-body keypoints were estimated from 118 million video frames. To facilitate data exploration and reuse, we have shared AJILE12 on The DANDI Archive in the Neurodata Without Borders (NWB) data standard and developed a browser-based dashboard.


2000 ◽  
Vol 278 (4) ◽  
pp. H1035-H1041 ◽  
Author(s):  
Naoko Aoyagi ◽  
Kyoko Ohashi ◽  
Shinji Tomono ◽  
Yoshiharu Yamamoto

A newly developed, very long-term (∼7 days) ambulatory monitoring system for assessing beat-to-beat heart rate variability (HRV) and body movements (BM) was used to study the mechanism(s) responsible for the long-period oscillation in human HRV. Data continuously collected from five healthy subjects were analyzed by 1) standard auto- and cross-spectral techniques, 2) a cross-Wigner distribution (WD; a time-frequency analysis) between BM and HRV for 10-s averaged data, and 3) coarse-graining spectral analysis for 600 successive cardiac cycles. The results showed 1) a clear circadian rhythm in HRV and BM, 2) a 1/ f β-type spectrum in HRV and BM at ultradian frequencies, and 3) coherent relationships between BM and HRV only at specific ultradian as well as circadian frequencies, indicated by significant ( P < 0.05) levels of the squared coherence and temporal localizations of the covariance between BM and HRV in the cross-WD. In a single subject, an instance in which the behavioral (mean BM) and autonomic [HRV power >0.15 Hz and mean heart rate (HR)] rhythmicities were dissociated occurred when the individual had an irregular daily life. It was concluded that the long-term HRV in normal humans contained persistent oscillations synchronized with those of BM at ultradian frequencies but could not be explained exclusively by activity levels of the subjects.


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