Progress in ionizing radiation resistance modification of polymer materials

Abstract With the wide application of polymer materials, much attention has been paid to the modification methods of polymer materials with high-energy radiation resistance to satisfy special environment, such as nuclear industry, space technology, medical equipmen. In this review, progress in ionizing radiation resistance modification of polymer materials is introduced in depth and different modification methods are compared. Finally, future perspectives of this field are discussed.

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Directed Evolution of Ionizing Radiation Resistance in Escherichia coli

Journal of Bacteriology ◽

10.1128/jb.00502-09 ◽

2009 ◽

Vol 191 (16) ◽

pp. 5240-5252 ◽

Cited By ~ 83

Author(s):

Dennis R. Harris ◽

Steve V. Pollock ◽

Elizabeth A. Wood ◽

Reece J. Goiffon ◽

Audrey J. Klingele ◽

...

Keyword(s):

Escherichia Coli ◽

Ionizing Radiation ◽

Directed Evolution ◽

Radiation Resistance ◽

Bacterial Species ◽

Repair System ◽

Multiple Alleles ◽

Evolutionary Pathways ◽

K 12 ◽

Ionizing Radiation Resistance

ABSTRACT We have generated extreme ionizing radiation resistance in a relatively sensitive bacterial species, Escherichia coli, by directed evolution. Four populations of Escherichia coli K-12 were derived independently from strain MG1655, with each specifically adapted to survive exposure to high doses of ionizing radiation. D37 values for strains isolated from two of the populations approached that exhibited by Deinococcus radiodurans. Complete genomic sequencing was carried out on nine purified strains derived from these populations. Clear mutational patterns were observed that both pointed to key underlying mechanisms and guided further characterization of the strains. In these evolved populations, passive genomic protection is not in evidence. Instead, enhanced recombinational DNA repair makes a prominent but probably not exclusive contribution to genome reconstitution. Multiple genes, multiple alleles of some genes, multiple mechanisms, and multiple evolutionary pathways all play a role in the evolutionary acquisition of extreme radiation resistance. Several mutations in the recA gene and a deletion of the e14 prophage both demonstrably contribute to and partially explain the new phenotype. Mutations in additional components of the bacterial recombinational repair system and the replication restart primosome are also prominent, as are mutations in genes involved in cell division, protein turnover, and glutamate transport. At least some evolutionary pathways to extreme radiation resistance are constrained by the temporally ordered appearance of specific alleles.

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Bacterial sensitivity to UV light as a model for ionizing radiation resistance

Journal of Microbiological Methods ◽

10.1016/0167-7012(93)90029-h ◽

1993 ◽

Vol 18 (2) ◽

pp. 127-136 ◽

Cited By ~ 15

Author(s):

Andrew A. Arrange ◽

Tommy J. Phelps ◽

Robert E. Benoit ◽

Anthony V. Palumbo ◽

David C. White

Keyword(s):

Ionizing Radiation ◽

Radiation Resistance ◽

Uv Light ◽

Bacterial Sensitivity ◽

Ionizing Radiation Resistance

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A variant of the Escherichia coli anaerobic transcription factor FNR exhibiting diminished promoter activation function enhances ionizing radiation resistance

PLoS ONE ◽

10.1371/journal.pone.0199482 ◽

2019 ◽

Vol 14 (1) ◽

pp. e0199482 ◽

Cited By ~ 2

Author(s):

Steven T. Bruckbauer ◽

Joseph D. Trimarco ◽

Camille Henry ◽

Elizabeth A. Wood ◽

John R. Battista ◽

...

Keyword(s):

Escherichia Coli ◽

Transcription Factor ◽

Ionizing Radiation ◽

Radiation Resistance ◽

Activation Function ◽

Promoter Activation ◽

Ionizing Radiation Resistance

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Downregulation of Survivin Gene Expression Affects Ionizing Radiation Resistance of Human T98 Glioma Cells

Cellular and Molecular Neurobiology ◽

10.1007/s10571-017-0560-7 ◽

2017 ◽

Vol 38 (4) ◽

pp. 861-868 ◽

Cited By ~ 3

Author(s):

Jicheng Li ◽

Yong Han ◽

Dai Zhou ◽

Youxin Zhou ◽

Ming Ye ◽

...

Keyword(s):

Gene Expression ◽

Ionizing Radiation ◽

Radiation Resistance ◽

Glioma Cells ◽

Survivin Gene ◽

Ionizing Radiation Resistance

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Untargeted metabolite profiling reveals that nitric oxide bioynthesis is an endogenous modulator of carotenoid biosynthesis in Deinococcus radiodurans and is required for extreme ionizing radiation resistance

Archives of Biochemistry and Biophysics ◽

10.1016/j.abb.2015.10.010 ◽

2016 ◽

Vol 589 ◽

pp. 38-52 ◽

Cited By ~ 9

Author(s):

Alex Hansler ◽

Qiuying Chen ◽

Yuliang Ma ◽

Steven S. Gross

Keyword(s):

Nitric Oxide ◽

Ionizing Radiation ◽

Radiation Resistance ◽

Metabolite Profiling ◽

Deinococcus Radiodurans ◽

Carotenoid Biosynthesis ◽

Endogenous Modulator ◽

Untargeted Metabolite Profiling ◽

Ionizing Radiation Resistance

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Heat-Shock Induction of Ionizing Radiation Resistance in Saccharomyces cerevisiae. Transient Changes in Growth Cycle Distribution and Recombinational Ability

Radiation Research ◽

10.2307/3575853 ◽

1982 ◽

Vol 92 (1) ◽

pp. 182 ◽

Cited By ~ 22

Author(s):

R. E. J. Mitchel ◽

D. P. Morrison

Keyword(s):

Saccharomyces Cerevisiae ◽

Heat Shock ◽

Ionizing Radiation ◽

Radiation Resistance ◽

Growth Cycle ◽

Ionizing Radiation Resistance ◽

Heat Shock Induction

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Ionizing Radiation for Preparation and Functionalization of Membranes and Their Biomedical and Environmental Applications

Membranes ◽

10.3390/membranes9120163 ◽

2019 ◽

Vol 9 (12) ◽

pp. 163 ◽

Cited By ~ 1

Author(s):

Casimiro ◽

Ferreira ◽

Leal ◽

Pereira ◽

Monteiro

Keyword(s):

Ionizing Radiation ◽

Low Cost ◽

High Energy ◽

Environmental Applications ◽

Radiation Processing ◽

Processing Technologies ◽

High Energy Radiation ◽

X Ray ◽

Radiation Sources ◽

Wide Range

The use of ionizing radiation processing technologies has proven to be one of the most versatile ways to prepare a wide range of membranes with specific tailored functionalities, thus enabling them to be used in a variety of industrial, environmental, and biological applications. The general principle of this clean and environmental friendly technique is the use of various types of commercially available high-energy radiation sources, like 60Co, X-ray, and electron beam to initiate energy-controlled processes of free-radical polymerization or copolymerization, leading to the production of functionalized, flexible, structured membranes or to the incorporation of functional groups within a matrix composed by a low-cost polymer film. The present manuscript describes the state of the art of using ionizing radiation for the preparation and functionalization of polymer-based membranes for biomedical and environmental applications.

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