scholarly journals Synthesis and Characterization of Dextran coated Iron Oxide Nanoparticles as a T1 Contrast Agent

2021 ◽  
Vol 2114 (1) ◽  
pp. 012037
Author(s):  
Z Ra’ad ◽  
L Q Al-Karam ◽  
N K Abid Alsahib

Abstract This is a second part of iron oxide nanoparticles synthesis by co-precipitation method with various PH values. This study includes stabilizing iron oxide nanoparticles with dextran of molecular weight 10000 Da by aqueous route, then study its characteristics with AFM, FTIR and VSM also using the stabilized material as a contrast agent in T1-weighted image then compare the contrast enhancement with gadolinium based commercially available contrast agent (MagnevistTM). Ph values were (7,11,14), all samples were injected to mice bodies then imaged with MRI best result of T1 contrast enhancement was obtained from sample with Ph 14 compared with gadolinium-based T1 contrast agent with no toxic effects.

Nanoscale ◽  
2021 ◽  
Author(s):  
Maximilian O. Besenhard ◽  
Luca Panariello ◽  
Céline Kiefer ◽  
Alec P. LaGrow ◽  
Liudmyla Storozhuk ◽  
...  

Small iron oxide nanoparticles (IONPs) were synthesised in water via co-precipitation by quenching particle growth after the magnetic iron oxide phase formed.


2013 ◽  
Vol 756 ◽  
pp. 74-79 ◽  
Author(s):  
Bashiru Kayode Sodipo ◽  
Azlan Abdul Aziz

Superparamagnetic iron oxide nanoparticles (SPION) of sizes 5 to10 nm were synthesized by the co-precipitation method. They are coated with silica nanoparticles using sonication method. The SPION was produced under the optimum pH of 10, peptized in acidic medium and redispersed in water. The silica nanoparticles were produced through the Stöbermethod. Sonochemical coating of silica nanoparticle on the SPION was successfulat a pH value lower than 5. Otherwise, at higher pH value (but lower than point zero charge (PZC)), the SPION were found to be unstable. Fast hydrolysis of triethoxyvinylsilane(TEVS) shows that silica forms its own particles without coating onto the surfaces of the SPION. Under optimized experimental condition, sonochemical method of coating silica nanoparticles onto the SPION can be considered as an alternative for effective and prompt method that rely mainly on pH of the suspension.


2017 ◽  
Vol 41 (5) ◽  
pp. 2055-2061 ◽  
Author(s):  
Tokeer Ahmad ◽  
Ruby Phul ◽  
Nafeesa Khatoon ◽  
Meryam Sardar

Iron oxide nanoparticles (IONPs) were preparedviaa co-precipitation method and were then characterized and evaluated for their antibacterial activity after modification withOcimum sanctumleaf extract.


2015 ◽  
Vol 15 (5) ◽  
pp. 3870-3878 ◽  
Author(s):  
S. Vikram ◽  
M. Dhakshnamoorthy ◽  
R. Vasanthakumari ◽  
A. R. Rajamani ◽  
Murali Rangarajan ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Xiao-Chen Yang ◽  
Yun-Long Shang ◽  
Yin-Hua Li ◽  
Jing Zhai ◽  
Neil R. Foster ◽  
...  

Monodisperse iron oxide nanoparticles could be successfully synthesized with two kinds of precipitants through a precipitation method. As-prepared nanoparticles in the size around 10 nm with regular spherical-like shape were achieved by adjusting pH values. NaOH and NH3·H2O were used as two precipitants for comparison. The average size of nanoparticles with NH3·H2O precipitant got smaller and represented better dispersibility, while nanoparticles with NaOH precipitant represented better magnetic property. This work provided a simple method without using any organic solvents, organic metal salts, or surfactants which could easily obtain monodisperse nanoparticles with tunable morphology.


2017 ◽  
Vol 105 (2) ◽  
Author(s):  
Gehan E. Sharaf El-Deen ◽  
Neama G. Imam ◽  
Refaat R. Ayoub

AbstractSuperparamagnetic iron oxide nanoparticles (IO-MNPs) coated with natural polymers, starch (IO-S MNPs) and dextrin (IO-D MNPs), were synthesized by modified co-precipitation method. IO and hybrid-IO-MNPs were characterized by XRD, SEM, HRTEM, FT-IR spectroscopy, vibrating sample magnetometer (VSM) and zeta potential (ZP). IO-S MNPs and IO-D MNPs have IO core-shell structure with core of 10.8 nm and 13.8 nm and shell of 7.5 nm and 5.9 nm, respectively. The efficiency of the hybrid IO-MNPs for sorption of


RSC Advances ◽  
2015 ◽  
Vol 5 (24) ◽  
pp. 18420-18428 ◽  
Author(s):  
A. B. Salunkhe ◽  
V. M. Khot ◽  
J. M. Ruso ◽  
S. I. Patil

Superparamagnetic iron oxide nanoparticles are synthesized through the co precipitation method by using the new generation base diisopropylamine (DIPA) which electrostatically complexes with the iron ions, reduces them and subsequently caps the nanoparticles.


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