The effects of pile diameter, the property of pile end bearing stratum, the material parameters of pile shaft and the changes of pile length on the bearing performance of extra-long and large-diameter single pile were examined with the finite element software ABAQUS to make the numerical simulation analysis, by establishing the overall axial symmetry model, which was based on the data of static load test of single pile at the Yellow River Bridge site. The results show that the ultimate bearing capacity of single pile, the stiffness and the end resistance ratio would increase gradually, whereas the compression settlement ratio decreases slowly; the pile end grouting can significantly increase the ultimate loads, and therefore, improve the bearing performance of piles, but it has little effect on the stiffness of pile when loading was smaller; the elastic modulus of pile shaft has no effect on the ultimate bearing capacity of friction piles, little on the end resistance ratio, while the pile compression settlement ratio would gradually decrease and the stiffness would increased with the increase of the elastic modulus of pile shaft, and this increase of stiffness would slow down with the increase of elastic modulus of pile shaft; it is unreasonable to improve the ultimate bearing capacity of extra-long single pile only by means of increasing the pile length.