scholarly journals Antioxidant activity and bioactive compounds of extracts from the Algerian plant Moltkia ciliata

2021 ◽  
Vol 1204 (1) ◽  
pp. 012001
Author(s):  
Soumaia Chihi ◽  
Oumelkheir Rahim ◽  
Ali Douadi ◽  
Rabab Zatout
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Antioxidant Properties ◽  
Etoac Extract ◽  
Potential Source ◽  
Effective Antioxidant ◽  
The Difference ◽  
In Vitro Antioxidant Activity

Abstract In the present study, we reported the evaluation of antioxidant properties using electrochemical and spectrophotometric assays and determination of total bioactive compounds content of the ethyl acetate (EtOAc) and n-butanol (n-BuOH) extracts of Moltkia ciliata growing in Algeria. The results obtained showed that the EtOAc extract was rich in bioactive compounds, which showed the most effective antioxidant capacity in all tests compared to the n-BuOH extract. This was confirmed by the chromatographic analysis and HPLC of the extract of many compounds in different quantities. The difference in antioxidant activity can be explained by differences in the levels of polyphenols and flavonoids. The study concludes this plant is a rich source of phenols and flavonoids, and also showed good in-vitro antioxidant activity by all methods. Thus, the plant M. ciliata can be explored as a potential source of natural antioxidant.

scholarly journals Evaluation of Bioactive Compounds, in Vitro Antioxidant Activity and Acute Toxicity of Ethanol Extract of Morinda lucida Leaves

2021 ◽  
pp. 32-38
Author(s):  
F. M. Idih ◽  
O. V. Alagbe ◽  
V. D. Sheneni ◽  
J. Ebune
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Lethal Dose ◽  
Ethanol Extract ◽  
Gas Chromatography Mass Spectrometry ◽  
Medium Size ◽  
Traditional Treatment ◽  
In Vitro Antioxidant Activity

Plants are known to contain phytochemicals of pharmacological relevance and as such have been utilized in the treatment and management of various diseases. Morinda lucida, a medium size tropical tree belonging to the rubiaceae family and widely distributed in Africa is one of these plants. It has been reportedly used in the traditional treatment and management of diseases. This study is aimed at identifying compounds with pharmacological relevance in the ethanol extract of Morinda lucida leaves, the antioxidant activity and lethal dose determination of the extract. The leaves of Morinda lucida was extracted with ethanol; phytochemical and bioactive compounds analysis, in vitro antioxidant activity and lethal dose (LD50) determinations were carried out. It was observed in the study that the extract contains alkaloids, quinines, quinones, flavonoids and tannins. The gas chromatography mass spectrometry (GC-MS) identified phenol 2, 4-bis (1,1-dimethylethyl) (2.82%), Stilbenes (12.32%), Phenoxazine (2.60%) and Benz(cd) indol-2(1H)-one, 1-methyl- (2.60%) amongst other compounds in the extract. The in vitro antioxidant activity evaluation of the extract revealed that it possesses a significant antioxidant activity which increased with increasing concentration. The LD50 determination revealed the extract was safe as there was no death recorded even at a dose as high as 5000 mg/kg. This study shows that Morinda lucida possesses enormous pharmacological potentials.

scholarly journals Bioactive compounds content and total antioxidant activity of two savoy cabbages

2014 ◽  
Vol 32 (No. 6) ◽  
pp. 549-554 ◽  
Author(s):  
M.A. Fernández-León ◽  
M. Lozano ◽  
D. González ◽  
M.C. Ayuso ◽  
M.F. Fernández-León
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Total Phenolic Content ◽  
Phenolic Content ◽  
Total Phenolic ◽  
Total Antioxidant Activity ◽  
Fresh Weight ◽  
Total Antioxidant ◽  
In Vitro Antioxidant Activity

The bioactive compounds, as well as the in vitro antioxidant activity of two Savoy cabbage cultivars, Dama and Leticia, grown in west of Spain under similar conditions were identified, quantified and compared. We found that cv. Dama presented in general betters results when compared with cv. Leticia. Cv. Dama presented higher concentrations of chlorophyll a (2.26 mg/100 g fresh weight), total phenolic content (102.71 mg of chlorogenic acid equivalent/100 g fresh weight) and total intact glucosinolates (195.22 µmol of sinigrin equivalent/100 g fresh weight). Thus, cv. Dama exhibited higher values of in vitro antioxidant activity.  

Determination of in vitro antioxidant activity of fennel (Foeniculum vulgare) seed extracts

LWT ◽  
2003 ◽  
Vol 36 (2) ◽  
pp. 263-271 ◽  
Author(s):  
Münir Oktay ◽  
İlhami Gülçin ◽  
Ö.İrfan Küfrevioğlu
Keyword(s):  
Antioxidant Activity ◽  
Foeniculum Vulgare ◽  
Seed Extracts ◽  
In Vitro Antioxidant Activity

scholarly journals Evaluation of physicochemical and antioxidant properties of nanosized copolymeric micelles loaded with kaempferol

Pharmacia ◽  
2020 ◽  
Vol 67 (2) ◽  
pp. 49-54
Author(s):  
Krassimira Yoncheva ◽  
Nadia Hristova-Avakumova ◽  
Vera Hadjimitova ◽  
Trayko Traykov ◽  
Petar Petrov
Keyword(s):  
Antioxidant Activity ◽  
Propylene Oxide ◽  
Encapsulation Efficiency ◽  
Antioxidant Properties ◽  
In Vitro Release ◽  
Before And After ◽  
Poly Propylene ◽  
Vitro Release

The study was focused on the evaluation of two copolymers as micellar carriers for kaempferol delivery. The copolymers comprised identical hydrophilic blocks of poly(2-(dimethylamino)ethyl methacrylate and different hydrophobic blocks of either poly(ε-caprolactone) (PDMAEMA9-b-PCL70-b-PDMAEMA9) or poly(propylene oxide) (PDMAEMA13-b-PPO69-b-PDMAEMA13). The calculation of Flory-Huggins parameters and determination of encapsulation efficiency showed that PDMAEMA-b-PCL-b-PDMAEMA copolymer possessed higher capacity for kaempferol loading. The diameter of the micelles before and after lyophilization was not changed, suggesting that the micelles could be lyophilized and redispersed before administration. The in vitro release of kaempferol from PDMAEMA-b-PPO-b-PDMAEMA micelles was faster than the release from PDMAEMA-b-PCL-b-PDMAEMA micelles, probably due to the higher affinity of kaempferol to this copolymer. Further, the higher affinity resulted in a retention of antioxidant activity of kaempferol in the presence of DPPH and KO2 radicals. Thus, PDMAEMA-PCL-PDMAEMA was considered more appropriate carrier because of the higher encapsulation efficiency and preservation of antioxidant activity of the drug.

Sign in / Sign up

Export Citation Format

Share Document