Differential Impact of Resistance-Associated Mutations to Protease Inhibitors and Nonnucleoside Reverse Transcriptase Inhibitors on HIV-1 Replication Capacity

Differential Impact ◽

Hiv 1

(Alkylamino) piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1IIIB with reduced replication phenotypes.

Journal of Virology ◽

10.1128/jvi.70.6.3698-3705.1996 ◽

1996 ◽

Vol 70 (6) ◽

pp. 3698-3705 ◽

Cited By ~ 22

Author(s):

R A Olmsted ◽

D E Slade ◽

L A Kopta ◽

S M Poppe ◽

T J Poel ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Broad Spectrum ◽

Drug Resistant ◽

Immunodeficiency Virus ◽

Hiv 1

Structure of HIV-1 nonnucleoside reverse transcriptase inhibitors derivatives of N-benzyl-benzimidazole with different substituents in position 4

Journal of Molecular Structure ◽

10.1016/j.molstruc.2009.10.034 ◽

2010 ◽

Vol 963 (2-3) ◽

pp. 188-193 ◽

Cited By ~ 3

Author(s):

Natasza E. Ziółkowska ◽

Christopher J. Michejda ◽

Grzegorz D. Bujacz

Keyword(s):

Reverse Transcriptase ◽

Derivatives Of ◽

Hiv 1

Superiority of Protease Inhibitors over Nonnucleoside Reverse-Transcriptase Inhibitors when Highly Active Antiretroviral Therapy Is Resumed after Treatment Interruption

Clinical Infectious Diseases ◽

10.1086/432887 ◽

2005 ◽

Vol 41 (6) ◽

pp. 897-900 ◽

Cited By ~ 8

Author(s):

P. Barreiro ◽

C. de Mendoza ◽

J. Gonzalez-Lahoz ◽

V. Soriano

Keyword(s):

Antiretroviral Therapy ◽

Reverse Transcriptase ◽

Protease Inhibitors ◽

Highly Active Antiretroviral Therapy ◽

Treatment Interruption ◽

Highly Active

PIN20 THE COST-EFFECTIVENESS OF ANTIRETROVIRAL REGIMENS CONTAINING PROTEASE INHIBITORS (PIS) OR NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS (NNRTI) IN THE TREATMENT OF HIV-INFACTED INDIVIDUALS IN POLAND

Value in Health ◽

10.1016/s1098-3015(10)61498-2 ◽

2002 ◽

Vol 5 (6) ◽

pp. 569

Author(s):

E Kowalik ◽

MK Jakubczyk ◽

MP Niewada ◽

B Kamiñski

Keyword(s):

Cost Effectiveness ◽

Reverse Transcriptase ◽

Protease Inhibitors ◽

The Cost

Application of 3D-QSAR, Pharmacophore, and Molecular Docking in the Molecular Design of Diarylpyrimidine Derivatives as HIV-1 Nonnucleoside Reverse Transcriptase Inhibitors

International Journal of Molecular Sciences ◽

10.3390/ijms19051436 ◽

2018 ◽

Vol 19 (5) ◽

pp. 1436 ◽

Cited By ~ 12

Author(s):

Genyan Liu ◽

Wenjie Wang ◽

Youlan Wan ◽

Xiulian Ju ◽

Shuangxi Gu

Keyword(s):

Molecular Docking ◽

Reverse Transcriptase ◽

Molecular Design ◽

3D Qsar ◽

Hiv 1

Mechanisms of HIV-1 drug resistance to nucleoside and nonnucleoside reverse transcriptase inhibitors

Molecular Biology ◽

10.1134/s0026893311010092 ◽

2011 ◽

Vol 45 (1) ◽

pp. 93-109 ◽

Cited By ~ 7

Author(s):

G. N. Nikolenko ◽

A. T. Kotelkin ◽

S. F. Oreshkova ◽

A. A. Ilyichev

Keyword(s):

Drug Resistance ◽

Reverse Transcriptase ◽

Hiv 1

Fragment hopping-based discovery of novel sulfinylacetamide-diarylpyrimidines (DAPYs) as HIV-1 nonnucleoside reverse transcriptase inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.111874 ◽

2020 ◽

Vol 185 ◽

pp. 111874 ◽

Cited By ~ 3

Author(s):

Sheng Han ◽

Yali Sang ◽

Yan Wu ◽

Yuan Tao ◽

Christophe Pannecouque ◽

...

Keyword(s):

Reverse Transcriptase ◽

Hiv 1

Therapeutic Effects of Nonnucleoside Reverse Transcriptase Inhibitors on the Central Nervous System in HIV-1–Infected Patients

JAIDS Journal of Acquired Immune Deficiency Syndromes ◽

10.1097/00042560-200204010-00006 ◽

2002 ◽

Vol 29 (4) ◽

pp. 363-367

Author(s):

Hans Jürgen von Giesen ◽

Hubertus Köller ◽

Albert Theisen ◽

Gabriele Arendt

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Reverse Transcriptase ◽

Therapeutic Effects ◽

The Central Nervous System ◽

Hiv 1

Viro-immunological efficacy and tolerability of dolutegravir-based regimens compared to regimens based on other integrase strand inhibitors, protease inhibitors or non-nucleoside reverse transcriptase inhibitors in patients with acute HIV-1 infection: A multicenter retrospective cohort study

International Journal of Antimicrobial Agents ◽

10.1016/j.ijantimicag.2019.06.003 ◽

2019 ◽

Vol 54 (4) ◽

pp. 487-490 ◽

Cited By ~ 3

Author(s):

F. Lagi ◽

G. Baldin ◽

M. Colafigli ◽

A. Capetti ◽

G. Madeddu ◽

...

Keyword(s):

Cohort Study ◽

Reverse Transcriptase ◽

Protease Inhibitors ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Acute Hiv ◽

Hiv 1

Crystal structures of HIV-1 nonnucleoside reverse transcriptase inhibitors: N-benzyl-4-methyl-benzimidazoles

Journal of Molecular Structure ◽

10.1016/j.molstruc.2009.05.007 ◽

2009 ◽

Vol 930 (1-3) ◽

pp. 157-161 ◽

Cited By ~ 4

Author(s):

Natasza E. Ziółkowska ◽

Christopher J. Michejda ◽

Grzegorz D. Bujacz

Keyword(s):

Reverse Transcriptase ◽

Crystal Structures ◽

Hiv 1