NAS Recommends Methods for Safety Assessment of Altered Food Products/ Thailand Reverses Course on Genetically Altered Plants/ German Legislature Split on Genetically Modified Plants

2004 ◽  
Vol 23 (6) ◽  
pp. 752-753
2019 ◽  
Vol 70 (1) ◽  
pp. 699-726 ◽  
Author(s):  
Joachim Schiemann ◽  
Antje Dietz-Pfeilstetter ◽  
Frank Hartung ◽  
Christian Kohl ◽  
Jörg Romeis ◽  
...  

This review describes the current status and future challenges of risk assessment and regulation of plants modified by modern biotechniques, namely genetic engineering and genome editing. It provides a general overview of the biosafety and regulation of genetically modified plants and details different regulatory frameworks with a focus on the European situation. The environmental risk and safety assessment of genetically modified plants is explained, and aspects of toxicological assessments are discussed, especially the controversial debate in Europe on the added scientific value of untargeted animal feeding studies. Because RNA interference (RNAi) is increasingly explored for commercial applications, the risk and safety assessment of RNAi-based genetically modified plants is also elucidated. The production, detection, and identification of genome-edited plants are described. Recent applications of modern biotechniques, namely synthetic biology and gene drives, are discussed, and a short outlook on the future follows.


Plant Biology ◽  
2006 ◽  
Vol 8 (5) ◽  
pp. 662-672 ◽  
Author(s):  
S. B. Metzdorff ◽  
E. J. Kok ◽  
P. Knuthsen ◽  
J. Pedersen

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