scholarly journals Intranasal Adeno-Associated Virus Mediated Gene Delivery and Expression of Human Iduronidase in the Central Nervous System: A Noninvasive and Effective Approach for Prevention of Neurologic Disease in Mucopolysaccharidosis Type I

2017 ◽  
Vol 28 (7) ◽  
pp. 576-587 ◽  
Author(s):  
Lalitha R. Belur ◽  
Alexa Temme ◽  
Kelly M. Podetz-Pedersen ◽  
Maureen Riedl ◽  
Lucy Vulchanova ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Gene Delivery ◽  
Type I ◽  
Mucopolysaccharidosis Type ◽  
Neurologic Disease ◽  
Mucopolysaccharidosis Type I ◽  
Adeno Associated Virus ◽  
System A ◽  
The Central Nervous System

In vivo electroporation of the central nervous system: A non-viral approach for targeted gene delivery

2010 ◽  
Vol 92 (3) ◽  
pp. 227-244 ◽  
Author(s):  
Jochen De Vry ◽  
Pilar Martínez-Martínez ◽  
Mario Losen ◽  
Yasin Temel ◽  
Thomas Steckler ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Gene Delivery ◽  
In Vivo Electroporation ◽  
Targeted Gene Delivery ◽  
System A ◽  
The Central Nervous System

Mills' syndrome. A clinical case of a rare degenerative pathology of the central nervous system

2020 ◽  
pp. 57-60
Author(s):  
Konstantin Gulyabin
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neurological Diseases ◽  
Cortical Atrophy ◽  
Primary Lateral Sclerosis ◽  
System A ◽  
The Central Nervous System ◽  
Primary Lateral ◽  
Lateral Sclerosis ◽  
Mills Syndrome

Mills' syndrome is a rare neurological disorder. Its nosological nature is currently not completely determined. Nevertheless, Mills' syndrome is considered to be a rare variant of the degenerative pathology of the central nervous system – a variant of focal cortical atrophy. The true prevalence of this pathology is unknown, since this condition is more often of a syndrome type, observed in the clinical picture of a number of neurological diseases (primary lateral sclerosis, frontotemporal dementia, etc.) and is less common in isolated form.

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