Caffeine for the Treatment of Central Apnea in Trisomy 18: A Case Study in the Novel Use of Methylxanthines in Palliative Transport

Author(s):  
Sydney Ariagno ◽  
Megan Thorvilson ◽  
Lezlie Andersen ◽  
Christopher Collura
Keyword(s):  
TAPPI Journal ◽  
2012 ◽  
Vol 11 (10) ◽  
pp. 9-17
Author(s):  
ALESSANDRA GERLI ◽  
LEENDERT C. EIGENBROOD

A novel method was developed for the determination of linting propensity of paper based on printing with an IGT printability tester and image analysis of the printed strips. On average, the total fraction of the surface removed as lint during printing is 0.01%-0.1%. This value is lower than those reported in most laboratory printing tests, and more representative of commercial offset printing applications. Newsprint paper produced on a roll/blade former machine was evaluated for linting propensity using the novel method and also printed on a commercial coldset offset press. Laboratory and commercial printing results matched well, showing that linting was higher for the bottom side of paper than for the top side, and that linting could be reduced on both sides by application of a dry-strength additive. In a second case study, varying wet-end conditions were used on a hybrid former machine to produce four paper reels, with the goal of matching the low linting propensity of the paper produced on a machine with gap former configuration. We found that the retention program, by improving fiber fines retention, substantially reduced the linting propensity of the paper produced on the hybrid former machine. The papers were also printed on a commercial coldset offset press. An excellent correlation was found between the total lint area removed from the bottom side of the paper samples during laboratory printing and lint collected on halftone areas of the first upper printing unit after 45000 copies. Finally, the method was applied to determine the linting propensity of highly filled supercalendered paper produced on a hybrid former machine. In this case, the linting propensity of the bottom side of paper correlated with its ash content.


2020 ◽  
Vol 73 (3) ◽  
pp. 497-520
Author(s):  
Nicola Pozza

AbstractNumerous studies have dealt with the process of globalization and its various cultural products. Three such cultural products illustrate this process: Vikas Swarup’s novel Q and A (2005), the TV quiz show Kaun banega crorepati? (Who Wants to Be a Millionaire?), and Danny Boyle’s film Slumdog Millionaire (2008). The novel, the TV show and the film have so far been studied separately. Juxtaposing and comparing Q and A, Kaun banega crorepati, and Slumdog Millionaire provides an effective means to shed light on the dialogic and interactive nature of the process of globalization. It is argued through this case study that an analysis of their place of production, language and content, helps clarify the derivative concepts of “glocalization” and “grobalization” with regard to the way(s) contemporary cultural products respond to globalization.


2020 ◽  
Vol 35 (9) ◽  
pp. 2675-2679 ◽  
Author(s):  
Katharine Lawrence ◽  
Kathleen Hanley ◽  
Jennifer Adams ◽  
Daniel J Sartori ◽  
Richard Greene ◽  
...  

2008 ◽  
Vol 72 (1) ◽  
pp. 515-519 ◽  
Author(s):  
E. Valsami-Jones ◽  
D. Berhanu ◽  
A. Dybowska ◽  
S. Misra ◽  
A. R. Boccaccini ◽  
...  

AbstractIn recent years it has become apparent that the novel properties of nanomaterials may predispose them to a hitherto unknown potential for toxicity. A number of recent toxicological studies of nanomaterials exist, but these appear to be fragmented and often contradictory. Such discrepancies may be, at least in part, due to poor description of the nanomaterial or incomplete characterization, including failure to recognise impurities, surface modifications or other important physicochemical aspects of the nanomaterial. Herew em ake a casef or the importance of good quality, well-characterized nanomaterials for future toxicological studies, combined with reliable synthesis protocols, and we present our efforts to generate such materials. The model system for which we present results is TiO2 nanoparticles, currently used in a variety of commercial products.


2021 ◽  
Vol 9 (6) ◽  
pp. 624
Author(s):  
Antonino Cirello ◽  
Tommaso Ingrassia ◽  
Antonio Mancuso ◽  
Vincenzo Nigrelli ◽  
Davide Tumino

The process of designing a sail can be a challenging task because of the difficulties in predicting the real aerodynamic performance. This is especially true in the case of downwind sails, where the evaluation of the real shapes and aerodynamic forces can be very complex because of turbulent and detached flows and the high-deformable behavior of structures. Of course, numerical methods are very useful and reliable tools to investigate sail performances, and their use, also as a result of the exponential growth of computational resources at a very low cost, is spreading more and more, even in not highly competitive fields. This paper presents a new methodology to support sail designers in evaluating and optimizing downwind sail performance and manufacturing. A new weakly coupled fluid–structure interaction (FSI) procedure has been developed to study downwind sails. The proposed method is parametric and automated and allows for investigating multiple kinds of sails under different sailing conditions. The study of a gennaker of a small sailing yacht is presented as a case study. Based on the numerical results obtained, an analytical formulation for calculating the sail corner loads has been also proposed. The novel proposed methodology could represent a promising approach to allow for the widespread and effective use of numerical methods in the design and manufacturing of yacht sails.


Author(s):  
Michael Stubbs

Abstract In an influential book on literary linguistics, first published in 1981 and revised in 2007, Geoffrey Leech and his colleague Mick Short discuss linguistic methods of analysing long texts of prose fiction. This article develops their arguments in two ways: (1) by relating them to classic puzzles in the philosophy of science; and (2) by illustrating them with a computer-assisted study of Bram Stoker’s 1897 novel Dracula. This case study shows that software can identify a linguistic feature of the novel which is central to its major themes, but which is unlikely to be consciously noticed by human readers. Quantitative data on the novel show that it contains a large number of negatives. Their function is often to deny something which would normally be expected, and therefore to express the protagonists’ distrust of their own senses in the extraordinary world in which they find themselves.


2021 ◽  
Author(s):  
Stanley Oifoghe ◽  
Nora Alarcon ◽  
Lucrecia Grigoletto

Abstract Hydrocarbons are bypassed in known fields. This is due to reservoir heterogeneities, complex lithology, and limitations of existing technology. This paper seeks to identify the scenarios of bypassed hydrocarbons, and to highlight how advances in reservoir characterization techniques have improved assessment of bypassed hydrocarbons. The present case study is an evaluation well drilled on the continental shelf, off the West African Coastline. The targeted thin-bedded reservoir sands are of Cenomanian age. Some technologies for assessing bypassed hydrocarbon include Gamma Ray Spectralog and Thin Bed Analysis. NMR is important for accurate reservoir characterization of thinly bedded reservoirs. The measured NMR porosity was 15pu, which is 42% of the actual porosity. Using the measured values gave a permeability of 5.3mD as against the actual permeability of 234mD. The novel model presented in this paper increased the porosity by 58% and the permeability by 4315%.


2021 ◽  
Vol 40 (3) ◽  
pp. 233-247 ◽  
Author(s):  
Alicja Relidzyńska

Expressions of nostalgia for the 1980s in contemporary American culture are diverse. The most interesting of them go beyond a wistful longing for the past. A complex ‘nostalgia trip’ offered by Netflix’s Stranger Things serves as a notable case study of a distinctive type of this sentiment. Instead of yearning for the restoration of previous times, it plays with past aesthetics in a critically articulate manner, effectively demythologizing the depicted decade. I argue that this significant alteration of the traditional sentiment stems largely from the recent acknowledgment of the Anthropocene and its irreversibility. This article aims to examine the peculiar, self-aware, paradoxical nostalgia, which is coloured by the current, Anthropocene-induced fears for the environment and, thus, our future. The analysis of Stranger Things – its thematics, genre, visuals and the meticulously reconstructed image of the presented era – draws parallels to the techniques employed by the ‘novel nostalgia’: bitter, ironic depiction of the past and references to natural phenomena. The study thus investigates the show at the intersection of contemporary nostalgia for the 1980s and the cultural repercussions of the Anthropocene. In so doing, it will unravel the innovation in the programme’s discourse on the 1980s decade in American culture.


2003 ◽  
Vol 103 (7) ◽  
pp. 81-83 ◽  
Author(s):  
Beth Glassford
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document