Spinal Cord Diffusion Tensor Imaging and Fiber Tracking Can Identify White Matter Tract Disruption and Glial Scar Orientation Following Lateral Funiculotomy

2005 ◽  
Vol 22 (12) ◽  
pp. 1388-1398 ◽  
Author(s):  
Eric D. Schwartz ◽  
Jeffrey Duda ◽  
Jed S. Shumsky ◽  
Emily T. Cooper ◽  
James Gee
Keyword(s):  
Spinal Cord ◽  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Diffusion Tensor ◽  
Fiber Tracking ◽  
Glial Scar ◽  
White Matter Tract

scholarly journals Noninvasive diffusion tensor imaging of evolving white matter pathology in a mouse model of acute spinal cord injury

2007 ◽  
Vol 58 (2) ◽  
pp. 253-260 ◽  
Author(s):  
Joong Hee Kim ◽  
David N. Loy ◽  
Hsiao-Fang Liang ◽  
Kathryn Trinkaus ◽  
Robert E. Schmidt ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Mouse Model ◽  
Diffusion Tensor ◽  
Acute Spinal Cord Injury ◽  
Cord Injury ◽  
White Matter Pathology

scholarly journals Non-invasive diffusion tensor imaging detects white matter degeneration in the spinal cord of a mouse model of amyotrophic lateral sclerosis

NeuroImage ◽  
2011 ◽  
Vol 55 (2) ◽  
pp. 455-461 ◽  
Author(s):  
Clare K. Underwood ◽  
Nyoman D. Kurniawan ◽  
Tim J. Butler ◽  
Gary J. Cowin ◽  
Robyn H. Wallace
Keyword(s):  
Spinal Cord ◽  
Amyotrophic Lateral Sclerosis ◽  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Mouse Model ◽  
Diffusion Tensor ◽  
Non Invasive ◽  
White Matter Degeneration ◽  
Lateral Sclerosis

Diffusion tensor imaging: serial quantitation of white matter tract maturity in premature newborns

NeuroImage ◽  
2004 ◽  
Vol 22 (3) ◽  
pp. 1302-1314 ◽  
Author(s):  
Savannah C Partridge ◽  
Pratik Mukherjee ◽  
Roland G Henry ◽  
Steven P Miller ◽  
Jeffrey I Berman ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Diffusion Tensor ◽  
White Matter Tract ◽  
Premature Newborns

Diffusion Tensor Imaging of Brain Tumours at 3T: A Potential Tool for Assessing White Matter Tract Invasion?

2003 ◽  
Vol 58 (6) ◽  
pp. 455-462 ◽  
Author(s):  
S.J. Price ◽  
N.G. Burnet ◽  
T. Donovan ◽  
H.A.L. Green ◽  
A. Peña ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Brain Tumours ◽  
Diffusion Tensor ◽  
White Matter Tract ◽  
Potential Tool

Diffusion Tensor Imaging Tractography Tutorial and Introduction to Major White Matter Tract Anatomy and Function

Neurographics ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 62-74 ◽  
Author(s):  
T.A. Hijaz ◽  
E.N. McComb ◽  
S. Badhe ◽  
B.P. Liu ◽  
A.W. Korutz
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Diffusion Tensor ◽  
White Matter Tract ◽  
And Function ◽  
Diffusion Tensor Imaging Tractography

Migraine affects white-matter tract integrity: A diffusion-tensor imaging study

Cephalalgia ◽  
2015 ◽  
Vol 35 (13) ◽  
pp. 1162-1171 ◽  
Author(s):  
Catherine D Chong ◽  
Todd J Schwedt
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Corticospinal Tract ◽  
Diffusion Tensor ◽  
Mean Diffusivity ◽  
Imaging Study ◽  
White Matter Tract ◽  
Inferior Longitudinal Fasciculus ◽  
Left And Right ◽  
The Right

Background Specific white-matter tract alterations in migraine remain to be elucidated. Using diffusion tensor imaging (DTI), this study investigated whether the integrity of white-matter tracts that underlie regions of the “pain matrix” is altered in migraine and interrogated whether the number of years lived with migraine modifies fibertract structure. Methods Global probabilistic tractography was used to assess the anterior thalamic radiations, the corticospinal tracts and the inferior longitudinal fasciculi in 23 adults with migraine and 18 healthy controls. Results Migraine patients show greater mean diffusivity (MD) in the left and right anterior thalamic radiations, the left corticospinal tract, and the right inferior longitudinal fasciculus tract. Migraine patients also show greater radial diffusivity (RD) in the left anterior thalamic radiations, the left corticospinal tract as well as the left and right inferior longitudinal fasciculus tracts. No group fractional anisotropy (FA) differences were identified for any tracts. Migraineurs showed a positive correlation between years lived with migraine and MD in the right anterior thalamic radiations ( r = 0.517; p = 0.012) and the left corticospinal tract ( r = 0.468; p = 0.024). Conclusion Results indicate that white-matter integrity is altered in migraine and that longer migraine history is positively correlated with greater alterations in tract integrity.

IC-P-047: White matter tract changes in mild-to-moderate Alzheimer's disease revealed by tensor-based registration analyses of diffusion tensor imaging

2012 ◽  
Vol 8 (4S_Part_1) ◽  
pp. P31-P32 ◽  
Author(s):  
Shiva Keihaninejad ◽  
Hui Zhang ◽  
Natalie Ryan ◽  
Ian Malone ◽  
Chris Frost ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Diffusion Tensor ◽  
White Matter Tract

Identification of Severities of Spinal Cord Injury during Acute Phase in Rats by Diffusion Tensor Imaging

2020 ◽  
Author(s):  
Beike Chen ◽  
Qiang Tan ◽  
Weikang Zhao ◽  
Qiming Yang ◽  
Hongyan Zhang ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Diffusion Tensor ◽  
Motor Evoked Potentials ◽  
Ex Vivo ◽  
Female Rats ◽  
Aneurysm Clip ◽  
Cord Injury

Abstract Background: Diffusion tensor imaging (DTI) was an effective method to identify subtle changes to normal‐appearing white matter (WM). Here we analyzed the DTI data with other examinations, including motor evoked potentials (MEPs), histopathological images, and behavioral results, to reflect the lesion development in different degrees of spinal cord injury (SCI) in acute and subacute stage. Method: Except for 2 Sprague -Dawley rats died from anesthesia accident, the rest 42 female rats were randomized into 3 groups: control (n=6), moderate group (n=18), and severe group (n=18). Moderate (a 50-g aneurysm clip with 0.4-mm thickness spacer) or severe (a 50-g aneurysm clip with no spacer) contusion SCI at T8 vertebrae were induced. Then the electrophysiological assessments via MEPs, behavioral deterioration via the Basso, Beattie, and Bresnaha (BBB) scores, DTI data, and histopathology examination were analyzed. Results: In this study, we found that the damage of WM myelin, MEPs amplitude, BBB scores and the decreases in values of fractional anisotropy (FA) and axial diffusivity (AD) were more obvious in the severe injury group than that of the moderate group. Additionally, the FA and AD values could identify the extent of SCI in subacute and early acute SCI respectively, reflected in the robust correlations with MEPs and BBB scores. While the values of radial diffusivity (RD) showed no significant changes. Conclusions: Our data confirmed that DTI was a valuable in ex vivo imaging tool to identify damaged white matter tracts after graded SCI in rat, which may provide useful information for the early identification of the severity of SCI.

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