191AN INVESTIGATION OF THE RELATIONSHIP BETWEEN SLEEP DURATION AND COGNITIVE FUNCTION IN OLDER ADULTS

The aim of this study was to examine the association between lifestyle activities, including physical, cognitive, and social activities, and Alzheimer’s disease (AD) signature cortical thickness, as well as to examine the mediating role of AD signature cortical thickness in lifestyle activities and cognitive function in community-dwelling healthy older adults. Participants were 1026 older adults who met the study inclusion criteria. The physical, cognitive, and social activities of daily life were assessed using a self-reporting questionnaire. AD signature cortical thickness was determined using FreeSurfer software. Cognitive function was evaluated using the National Center for Geriatrics and Gerontology-Functional Assessment Tool. Path analysis (based on structural equation modeling (SEM)) of cognitive activities indicated that the direct path from cognitive activities to cognitive function was significant (p < 0.001), as was the direct path from AD signature cortical thickness to cognitive function (p < 0.001). Physical (p < 0.05) or social activities (p < 0.05) had a direct effect on cognitive function. However, AD signature cortical thickness did not mediate the relationship between physical or social activities and cognitive function. Our findings suggest that higher levels of cognitive activities later in life have a significant and positive direct effect on cognitive function. Additionally, AD signature cortical thickness significantly mediates the relationship between cognitive activities and cognitive function.

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Sleep Duration in Relation to Cognitive Function among Older Adults: A Systematic Review of Observational Studies

Neuroepidemiology ◽

10.1159/000442418 ◽

2016 ◽

Vol 46 (1) ◽

pp. 57-78 ◽

Cited By ~ 24

Author(s):

Elizabeth E. Devore ◽

Francine Grodstein ◽

Eva S. Schernhammer

Keyword(s):

Systematic Review ◽

Older Adults ◽

Cognitive Function ◽

Sleep Duration ◽

Observational Studies ◽

English Language ◽

Data Extraction ◽

Meta Analysis ◽

Short Sleep ◽

Sleep Parameters

Context: Increasing evidence suggests that circadian and sleep parameters influence cognitive function with aging. Objective: To evaluate observational studies of sleep duration and cognition in older adults. Data Sources: A systematic review of OVID Medline and PsycINFO through September 2015, and review of bibliographies from studies identified. Study Selection: English-language articles reporting observational studies of sleep duration and cognitive function in older populations. Data Extraction: Data extraction by 2 authors using predefined categories of desired information. Results: Thirty-two studies met our inclusion criteria, with nearly two-thirds published in the past 4 years. One-third of studies indicated that extreme sleep durations were associated with worse cognition in older adults. More studies favored an association with long vs. short sleep durations (35 vs. 26% of studies, respectively). Four studies found that greater changes in sleep duration over time were related to lower cognition. Study design and analytic methods were very heterogeneous across studies; therefore, meta-analysis was not undertaken. Limitations: We reviewed English-language manuscripts only, with a qualitative summary of studies identified. Conclusions and Implications of Key Findings: Observational studies of sleep duration and cognitive function in older adults have produced mixed results, with more studies suggesting that long (rather than short) sleep durations are related to worse cognition. Studies more consistently indicate that greater changes in sleep duration are associated with poor cognition. Future studies should be prospectively designed, with objective sleep assessment and longer follow-up periods; intervention studies are also needed to identify strategies for promoting cognitive health with aging.

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Education modifies the relationship between height and cognitive function in a cross-sectional population-based study of older adults in Rural South Africa

European Journal of Epidemiology ◽

10.1007/s10654-018-0453-1 ◽

2018 ◽

Vol 34 (2) ◽

pp. 131-139 ◽

Cited By ~ 5

Author(s):

Lindsay C. Kobayashi ◽

Lisa F. Berkman ◽

Ryan G. Wagner ◽

Kathleen Kahn ◽

Stephen Tollman ◽

...

Keyword(s):

South Africa ◽

Older Adults ◽

Cognitive Function ◽

Population Based ◽

Cross Sectional ◽

Rural South ◽

Population Based Study ◽

The Relationship ◽

Rural South Africa

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THE RELATIONSHIP BETWEEN THE EXPERIENCE OF SIGNIFICANT HISTORICAL EVENTS AND COGNITIVE FUNCTION AMONG OLDER ADULTS

Innovation in Aging ◽

10.1093/geroni/igz038.3406 ◽

2019 ◽

Vol 3 (Supplement_1) ◽

pp. S936-S937

Author(s):

Stephanie M Bergren ◽

Gabriella Dong

Keyword(s):

Older Adults ◽

Working Memory ◽

Cognitive Function ◽

Episodic Memory ◽

Processing Speed ◽

Historical Event ◽

Historical Events ◽

Chinese Older Adults ◽

Global Cognition ◽

The Relationship

Abstract Research has found relationships between experiencing stressful events and lower cognitive function in late life. However, there is little research about the cumulative experiences of significant historical events and cognitive function. Historical events may be unique compared to other life events due to their potential distal relationship to the individual. This study aims to examine the relationship between experiencing significant historical events and cognitive function among Chinese older adults. Data were drawn from the PINE Study, a cohort study of 3,126 US Chinese older adults collected from 2017-2019. Participants were asked if they experienced the Japanese invasion, famine, Great Leap Forward, Vietnam War, Cultural Revolution, and the Tian’anmen Square Protests. A composite score of 0-6 was calculated to count the number experienced. Cognitive function was measured through global cognition, episodic memory, working memory, processing speed, and Chinese MMSE. Linear and quantile regression were performed. Among the participants, 1908 (61.04%) were female with mean age of 75.33 (SD=8.22) years. The average number of historical events experienced was 2.36 (SD=1.44). After adjusting for covariates, every one additional historical event experience was associated with better global cognition (b=0.26, SE=0.009, p<.01), episodic memory (b = 0.045, SE=0.012, p<.001), and processing speed (b=0.383, SE=0.135, p<.01). Number of historical events was not significantly associated with working memory or C-MMSE. The positive relationship between historical events and some cognitive domains suggests a potential resilience effect after experiencing historical events. Future research should examine whether participants found events stressful and whether there are differential relationships to cognitive function.

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COGNITIVE AGING IN OLDER MINORITY POPULATIONS: LONGITUDINAL EVIDENCE FROM U.S. CHINESE OLDER ADULTS

Innovation in Aging ◽

10.1093/geroni/igz038.3001 ◽

2019 ◽

Vol 3 (Supplement_1) ◽

pp. S814-S814

Author(s):

XinQi Dong ◽

Melissa Simon

Keyword(s):

Older Adults ◽

Cognitive Function ◽

Longitudinal Data ◽

Cognitive Aging ◽

Well Being ◽

Population Based ◽

Minority Populations ◽

Physical Factors ◽

Chinese Older Adults ◽

The Relationship

Abstract The increasing diversity in the aging population warrants systematic investigations regarding ethnic differences related to cognitive aging and ethnicity-unique risk factors. However, due to the great paucity of population-based longitudinal data on cognitive aging in racial/ethnic minority populations, our knowledge in this area remain limited. The purpose of this symposium is, therefore, to examine various psychological, socio-cultural, and physical factors associated with cognitive aging among U.S. Chinese older adults, representing one of the biggest and fastest growing older minority populations nationally. Using longitudinal data from a population-based prospective cohort study, namely The Population Study of ChINese Elderly in Chicago (PINE) with a sample size of 3,157, this symposium presents findings from five research projects. Session 1 investigates the relationship between psychological well-being and change of cognitive function over four years. Session 2 and 3 examine the relationships between two socio-cultural factors and cognitive function. Specifically, session 2 investigates the associations between immigration-related factors and the incidence of cognitive impairment. Session 3 explores the relationship between cognitive function and Tai-Chi practice. Session 4 and 5 examine the relationships between two physical health indicators and cognitive aging. Specifically, session 4 examines the relationship between physical function and change of cognitive function over two years. Session 5 explores the association between body mass index and cognitive function decline over two years. Taken together, this symposium aims to further our knowledge of cognitive aging among ethnically/culturally diverse populations. The research findings will identify unique factors related to cognitive aging in older minority populations.

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The Relationship between Subjective Cognitive Decline and Health Literacy in Healthy Community-Dwelling Older Adults

Healthcare ◽

10.3390/healthcare8040567 ◽

2020 ◽

Vol 8 (4) ◽

pp. 567

Author(s):

Akio Goda ◽

Shin Murata ◽

Hideki Nakano ◽

Koji Nonaka ◽

Hiroaki Iwase ◽

...

Keyword(s):

Older Adults ◽

Health Literacy ◽

Cognitive Function ◽

Cognitive Decline ◽

Depression Scale ◽

Community Dwelling ◽

Subjective Cognitive Decline ◽

Healthy Community ◽

Community Dwelling Older Adults ◽

The Relationship

Few studies have examined the effects of health literacy on people at risk of developing dementia; its effects on the pathogenesis of subjective cognitive decline (SCD) are particularly unclear. This study aimed to clarify the relationship between health literacy and SCD in a population of healthy community-dwelling older adults. SCD status was assessed using the Cognitive Function domain of the Kihon Checklist (KCL-CF). Health literacy, in turn, was evaluated using the Communicative and Critical Health Literacy (CCHL) scale. Global cognitive function and depressive symptoms were evaluated using the Mini-Mental State Examination (MMSE) and a five-item version of the Geriatric Depression Scale (GDS-5), respectively. Participants who were suspected of having SCD were significantly older than their non-SCD peers, and scored significantly worse on the CCHL, MMSE, and GDS-5. In addition, SCD status was found to be associated with CCHL and GDS-5 scores, as well as age, according to a logistic regression analysis. These findings suggest that low health literacy is linked to SCD morbidity in healthy community-dwelling older adults and should prove useful in the planning of dementia prevention and intervention programs for this population.

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