Effect of Food Intake on Amino Acids in Human Plasma

1956 ◽  
Vol 4 (3) ◽  
pp. 275-278 ◽  
Author(s):  
E. STATEN WYNNE ◽  
CORA L. COTT
Keyword(s):  
Amino Acids ◽  
Food Intake ◽  
Human Plasma ◽  
Effect Of Food

Dietary intake of tryptophan tied emotion-related impulsivity in humans

2019 ◽  
pp. 1-8 ◽  
Author(s):  
Florian Javelle ◽  
Descartes Li ◽  
Philipp Zimmer ◽  
Sheri L. Johnson
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Food Intake ◽  
Essential Amino Acid ◽  
Food Habits ◽  
Psychological Disorder ◽  
Serotonin Synthesis ◽  
Amino Acid Tryptophan ◽  
Pass Through ◽  
Three Factor

Abstract. Emotion-related impulsivity, defined as the tendency to say or do things that one later regret during periods of heightened emotion, has been tied to a broad range of psychopathologies. Previous work has suggested that emotion-related impulsivity is tied to an impaired function of the serotonergic system. Central serotonin synthesis relies on the intake of the essential amino acid, tryptophan and its ability to pass through the blood brain barrier. Objective: The aim of this study was to determine the association between emotion-related impulsivity and tryptophan intake. Methods: Undergraduate participants (N = 25, 16 women, 9 men) completed a self-rated measure of impulsivity (Three Factor Impulsivity Index, TFI) and daily logs of their food intake and exercise. These data were coded using the software NutriNote to evaluate intakes of tryptophan, large neutral amino acids, vitamins B6/B12, and exercise. Results: Correlational analyses indicated that higher tryptophan intake was associated with significantly lower scores on two out of three subscales of the TFI, Pervasive Influence of Feelings scores r =  –.502, p < . 010, and (lack-of) Follow-Through scores, r =  –.407, p < . 050. Conclusion: Findings provide further evidence that emotion-related impulsivity is correlated to serotonergic indices, even when considering only food habits. It also suggests the need for more research on whether tryptophan supplements might be beneficial for impulsive persons suffering from a psychological disorder.

scholarly journals Determination of Branched-Chain Amino Acids in Food Supplements and Human Plasma by a CE-MS/MS Method with Enhanced Resolution

2021 ◽  
Vol 22 (15) ◽  
pp. 8261
Author(s):  
Juraj Piestansky ◽  
Michaela Matuskova ◽  
Ivana Cizmarova ◽  
Dominika Olesova ◽  
Peter Mikus
Keyword(s):  
Amino Acids ◽  
Human Plasma ◽  
Limit Of Detection ◽  
Background Electrolyte ◽  
Branched Chain Amino Acids ◽  
Fused Silica ◽  
Suitable Alternative ◽  
Enhanced Resolution ◽  
Validation Parameters ◽  
Branched Chain

In the presented study, a capillary electrophoresis-mass spectrometry method combining high separation efficiency and sensitive detection has been developed and validated, for the first time, to quantify branched chain amino acids (valine, isoleucine, leucine) in commercial food and sport supplement samples and human plasma samples. The separations were performed in a bare fused silica capillary. The background electrolyte was composed of 500 mM formic acid with pH 2.0. The plasma sample pretreatment was realized by simple protein precipitation with acetonitrile. Injection of a short zone of highly basic electrolyte before the sample injection and application of the negative pressure on the separation were accompanied by enhanced resolution of the isobaric amino acids—isoleucine and leucine. The developed method was characterized by favorable validation parameters, such as linearity (r2 > 0.99), accuracy and precision, the limit of detection, lower limit of quantification, or robustness. These parameters were more than sufficient for the quantification of branched chain amino acids in various samples. The determined concentrations of branched chain amino acids in food and sports supplements were in very good agreement with the content declared by the manufacturer. The investigated concentrations of branched chain amino acids were in the range 294.68–359.24 µM for valine, 91.76–95.67 µM for isoleucine, and 196.78–251.24 µM for leucine. These concentrations fall within the physiological limits. The developed CE-MS/MS method represents a suitable alternative to traditional approaches used in branched chain amino acid quality control and bioanalysis.

Effects of thermal processing on the allergenicity, structure, and critical epitope amino acids of crab tropomyosin

2021 ◽  
Author(s):  
Meng Liu ◽  
Tian-Jiao Han ◽  
Fei Huan ◽  
Meng-Si Li ◽  
Fei Xia ◽  
...  
Keyword(s):  
Amino Acids ◽  
Food Processing ◽  
Thermal Processing ◽  
Effect Of Food

Food processing can change the structure and immunoreactivity of purified allergens, but the effect of food processing on the immunoreactivity of the processed and purified allergen is still poorly understood.

Antibody to antihemophilic factor and its lack of reaction with hemophilic plasma

1965 ◽  
Vol 208 (3) ◽  
pp. 499-507 ◽  
Author(s):  
William D. McLester ◽  
Robert H. Wagner
Keyword(s):  
Amino Acids ◽  
Human Plasma ◽  
Measurable Effect ◽  
Rabbit Plasma ◽  
Canine Plasma ◽  
Inhibitor Titer ◽  
Antihemophilic Factor ◽  
Immune Rabbit

A partially purified preparation of canine antihemophilic factor was obtained utilizing amino acids as precipitating agents. This AHF preparation was used as the antigen in an immunologic investigation of canine hemophilia. Plasma from rabbits immunized with this preparation contained antibodies which inhibited the coagulation of normal canine plasma. The immune rabbit plasma inhibited AHF activity but had no measurable effect on any other procoagulant. Neither canine hemophilic plasma nor fractions prepared from canine hemophilic plasma contained an antigen capable of neutralizing the inhibitor (no cross-reacting material). The inhibitor titer was inversely proportional to the amount of added AHF in the form of a fraction of normal canine plasma. The inhibitor cross-reacted with human plasma AHF, but not with porcine, bovine, or rabbit AHF. The results of these studies are interpreted as providing further evidence that hemophilia, specifically canine hemophilia, is due to the failure of production of the antihemophilic factor.

Capillary electrophoretic and micellar electrokinetic separations of asymmetric dimethyl-L-arginine and structurally related amino acids: Quantitation in human plasma

2004 ◽  
Vol 27 (17-18) ◽  
pp. 1483-1490 ◽  
Author(s):  
Gabriele Trapp ◽  
Karsten Sydow ◽  
Maria T. Dulay ◽  
Tina Chou ◽  
John P. Cooke ◽  
...  
Keyword(s):  
Amino Acids ◽  
Human Plasma ◽  
Electrokinetic Separations ◽  
Capillary Electrophoretic

Effect of food intake on exercise fatigue in trained and untrained subjects

1985 ◽  
Vol 54 (3) ◽  
pp. 297-300 ◽  
Author(s):  
Amichai Arieli ◽  
Yoram Epstein ◽  
Shay Brill ◽  
Michael Winer ◽  
Yair Shapiro
Keyword(s):  
Food Intake ◽  
Effect Of Food ◽  
Exercise Fatigue

scholarly journals Monitoring of Irinotecan in Human Plasma: Sensitive Fluorescent Nanogels by Molecular Imprinting

2019 ◽  
Author(s):  
Martina Tommasini ◽  
Elena Pellizzoni ◽  
Valentina Iacuzzi ◽  
Elena Marangon ◽  
Paola Posocco ◽  
...  
Keyword(s):  
Amino Acids ◽  
Fluorescence Quenching ◽  
Human Plasma ◽  
Molecular Imprinting ◽  
Plasma Sample ◽  
Direct Detection ◽  
Fluorescent Nanoparticles ◽  
High Dilution ◽  
Molecularly Imprinted

A series of fluorescent molecularly imprinted nanogels to detect irinotecan (CPT11) were prepared and characterized. A set of amino acids and napthalimide polymerisable derivatives allowed to obtain polymers as soluble fluorescent nanoparticles by high dilution imprinted synthesis. The direct detection of irinotecan in human plasma was obtained by fluorescence quenching of the naphtalimide-based imprinted materials. The plasma sample treated with acetonitrile allowed the detection of irinotecan in the 10nM – 30μM range. The LOD was 9.4 nM, with within-run variability 10% and day to day variability 13%.<br>

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