Mediterranean dietary pattern and skin cancer risk: A prospective cohort study in French women

ABSTRACT Background The Mediterranean diet (MD) has been reported to be associated with lower cancer risk. However, while previous studies explored major single components of the MD, only 1 previous study has investigated adherence to the MD in relation to melanoma risk. Objective The aim of this study was to explore the relations between adherence to the MD and the risk of skin cancer, including melanomas, basal cell carcinomas (BCCs), and squamous cell carcinomas (SCCs). Design Etude Epidémiologique auprès de femmes de la Mutuelle Générale de l'Education Nationale (E3N) is a prospective cohort of 98,995 French women aged 40–65 y in 1990. Dietary data were collected via a validated food questionnaire in 1993. Adherence to the MD was assessed using a 9-unit dietary score that incorporates intakes of fruit, vegetables, legumes, cereal products, olive oil, fish, dairy products, meat products, and alcohol. We used Cox proportional hazards regression models to compute HRs and 95% CIs adjusted for age and main known skin cancer risk factors. Results From 1993 to 2008, a total of 2003 skin cancer cases were ascertained among 67,332 women, including 404 melanomas, 1367 BCCs, and 232 SCCs. Score of adherence to the MD was associated with lower risk of skin cancer (HR: 0.83; 95% CI: 0.73, 0.93 for high compared with low score, Ptrend = 0.001). MD score was also inversely and linearly associated with risks of melanoma (HR: 0.72; 95% CI: 0.54, 0.96; Ptrend = 0.02) and BCC (HR: 0.77; 95% CI: 0.66, 0.90; Ptrend = 0.0006) but not SCC (HR: 1.08; 95% CI: 0.75, 1.55; Ptrend = 0.68), although with no heterogeneity across skin cancer types (Pheterogeneity = 0.23). Conclusion These findings suggest that adherence to the MD is associated with a lower skin cancer risk in women, particularly melanoma and BCC. If confirmed in future research, these findings may have important implications in skin cancer prevention.

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Association of sunbed use with skin cancer risk factors in Europe: an investigation within the Euromelanoma skin cancer prevention campaign

Journal of the European Academy of Dermatology and Venereology ◽

10.1111/jdv.15307 ◽

2019 ◽

Vol 33 ◽

pp. 76-88 ◽

Cited By ~ 1

Author(s):

M. Suppa ◽

S. Gandini ◽

H. Njimi ◽

J.L. Bulliard ◽

O. Correia ◽

...

Keyword(s):

Risk Factors ◽

Skin Cancer ◽

Cancer Risk ◽

Cancer Prevention ◽

Skin Cancer Prevention ◽

Cancer Risk Factors ◽

Skin Cancer Risk ◽

Prevention Campaign ◽

Sunbed Use

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Photosensitizing Medications and Skin Cancer: A Comprehensive Review

Cancers ◽

10.3390/cancers13102344 ◽

2021 ◽

Vol 13 (10) ◽

pp. 2344

Author(s):

Elisabeth A. George ◽

Navya Baranwal ◽

Jae H. Kang ◽

Abrar A. Qureshi ◽

Aaron M. Drucker ◽

...

Keyword(s):

Skin Cancer ◽

Cancer Risk ◽

Cell Carcinoma ◽

The United States ◽

In Vivo Studies ◽

Cancer Risk Factors ◽

Skin Cancer Risk ◽

Number Of Patients

(1) The incidence of skin cancer is increasing in the United States (US) despite scientific advances in our understanding of skin cancer risk factors and treatments. In vitro and in vivo studies have provided evidence that suggests that certain photosensitizing medications (PSMs) increase skin cancer risk. This review summarizes current epidemiological evidence on the association between common PSMs and skin cancer. (2) A comprehensive literature search was conducted to identify meta-analyses, observational studies and clinical trials that report on skin cancer events in PSM users. The associated risks of keratinocyte carcinoma (squamous cell carcinoma and basal cell carcinoma) and melanoma are summarized, for each PSM. (3) There are extensive reports on antihypertensives and statins relative to other PSMs, with positive and null findings, respectively. Fewer studies have explored amiodarone, metformin, antimicrobials and vemurafenib. No studies report on the individual skin cancer risks in glyburide, naproxen, piroxicam, chlorpromazine, thioridazine and nalidixic acid users. (4) The research gaps in understanding the relationship between PSMs and skin cancer outlined in this review should be prioritized because the US population is aging. Thus the number of patients prescribed PSMs is likely to continue to rise.

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Skin cancer risk factors and screening among sexual minority and heterosexual women

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2019.02.024 ◽

2019 ◽

Vol 81 (4) ◽

pp. 1015-1018 ◽

Cited By ~ 3

Author(s):

Howa Yeung ◽

Marissa L.H. Baranowski ◽

Suephy C. Chen

Keyword(s):

Risk Factors ◽

Skin Cancer ◽

Cancer Risk ◽

Sexual Minority ◽

Cancer Risk Factors ◽

Skin Cancer Risk ◽

Heterosexual Women

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Analysis of skin cancer risk factors in immunosuppressed renal transplant patients shows high levels of UV-specific tandem CC to TT mutations of the p53 gene

Carcinogenesis ◽

10.1093/carcin/bgl191 ◽

2006 ◽

Vol 28 (3) ◽

pp. 724-731 ◽

Cited By ~ 30

Author(s):

S. Queille ◽

L. Luron ◽

A. Spatz ◽

M. F. Avril ◽

V. Ribrag ◽

...

Keyword(s):

Risk Factors ◽

Skin Cancer ◽

Renal Transplant ◽

Cancer Risk ◽

P53 Gene ◽

Cancer Risk Factors ◽

Skin Cancer Risk ◽

Transplant Patients ◽

Renal Transplant Patients

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P-047 Pilot Study of Skin Cancer Risk Factors and Photosensitivity in Patients with Inflammatory Bowel Disease Newly Initiating Immunosuppression

Inflammatory Bowel Diseases ◽

10.1097/01.mib.0000480149.83036.82 ◽

2016 ◽

Vol 22 ◽

pp. S24

Author(s):

Millie Long ◽

Kimberly Weaver ◽

Michael Kappelman ◽

Hans Herfarth ◽

Clare Pipkin

Keyword(s):

Risk Factors ◽

Inflammatory Bowel Disease ◽

Pilot Study ◽

Skin Cancer ◽

Cancer Risk ◽

Bowel Disease ◽

Cancer Risk Factors ◽

Skin Cancer Risk ◽

Inflammatory Bowel

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Web-Based Skin Cancer Prevention Training for Massage Therapists: Protocol for the Massage Therapists Skin Health Awareness, Referral, and Education Study (Preprint)

10.2196/preprints.13480 ◽

2019 ◽

Author(s):

Lois J Loescher ◽

Kelly M Heslin ◽

Laura A Szalacha ◽

Graciela E Silva ◽

Myra L Muramoto

Keyword(s):

Skin Cancer ◽

Cancer Risk ◽

Risk Reduction ◽

The United States ◽

Skin Cancer Prevention ◽

Health Awareness ◽

Web Based ◽

Skin Cancer Risk ◽

Massage Therapists ◽

Cancer Risk Reduction

BACKGROUND Skin cancer, the most common cancer in the United States, is costly and potentially deadly. Its burden can be reduced by early detection and prevention activities. The scope of skin cancer requires going beyond traditional health care providers to promote risk reduction. Partnering with the nonbiomedical workforce, such as massage therapists (MTs), may reach more individuals at risk. MTs see much of their clients’ skin and are amenable to performing skin cancer risk reduction activities during massage appointments. OBJECTIVE The objective of this study is to describe the Massage Therapists Skin Health Awareness, Referral, and Education protocol, presenting an overview of our systematic approach to developing rigorous e-training for MTs to enable them to be partners in skin cancer risk reduction. We also describe procedures for usability and feasibility testing of the training. METHODS We developed an integrated electronic learning system that includes electronic training (e-training) technology, simulated client interactions, online data collection instruments, and in-person assessment of MTs’ application of their training. RESULTS A total of 20 participants nationally scored the e-training as high for usability and satisfaction. We have screened an additional 77 MTs in Arizona for interest and eligibility, and currently have 37 enrolled participants, of whom 32 have completed the Web-based training. CONCLUSIONS The structured and rigorous development approach for this skin cancer risk reduction and brief behavioral intervention e-training for MTs begins to fill a gap in skin cancer risk reduction research. Iterative usability testing of our asynchronous Web-based training resulted in positive participant response. Our e-training approach offers greater learner accessibility, increased convenience, and greater scalability than the few existing programs and has the potential to reach many MTs nationally. INTERNATIONAL REGISTERED REPOR DERR1-10.2196/13480

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Skin Cancer Risk-Lowering Behaviors and Skincare Habits of Youth Ages 18-25 Years

International Journal of Studies in Nursing ◽

10.20849/ijsn.v3i2.314 ◽

2018 ◽

Vol 3 (2) ◽

pp. 14

Author(s):

Elizabeth Rainous ◽

Eli J. Herrmann ◽

Samuel P. Abraham

Keyword(s):

Skin Cancer ◽

Cancer Risk ◽

Risky Behaviors ◽

The Sun ◽

Cross Sectional ◽

Cancer Risk Factors ◽

Skin Cancer Risk ◽

Level Of Knowledge ◽

High Level ◽

Study Participants

Young adults are known for feeling invincible and thus engaging in risky behaviors. One such risky behavior is not protecting themselves from the sun, which can cause skin cancer. The purpose of this study was to determine the skin cancer risk-lowering behaviors and skincare habits among youth ages 18 to 25 years. The findings indicated that a high level of knowledge does not equal regular use of risk-lowering behaviors. This study was quantitative, cross-sectional, and non-experimental. The survey, consisting of 20 Likert-type scale statements, was given in a college consisting of about 2000 students of which 120 college undergraduates participated. Orem’s self-care theory was used as a guide for the study. Participants tended to agree that the use of sunscreen would help protect them from getting skin cancer (M=2.88, SD=0.57), and that sunlight causes skin cancer (M=2.80, SD=0.70). Despite having an adequate level of knowledge on skin cancer risk factors, individuals did not follow through with correct risk-lowering behaviors. For risk-lowering behaviors, more than half of the participants regularly used sunscreen when exposed to the sun (M=2.50, SD=0.90), and most never used tanning beds (M=1.20, SD=0.60).

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