scholarly journals Resting heart rate as a cardiovascular risk factor in hypertensive patients: An update

2020 ◽  
Author(s):  
Paolo Palatini
Keyword(s):  
Heart Rate ◽  
Population Studies ◽  
Large Body ◽  
Resting Heart Rate ◽  
General Population Studies ◽  
Prognostic Information ◽  
Night Time ◽  
Additional Risk ◽  
Hypertensive Patients ◽  
Clinical Conditions

Abstract A large body of evidence has shown that resting heart rate (RHR) holds important prognostic information in several clinical conditions. In the majority of the general population studies, a graded association between RHR and mortality from all causes, cardiovascular disease, ischaemic heart disease, and stroke has been observed. These associations appeared even stronger and more consistent in hypertensive patients. Studies performed with 24h ambulatory recording have shown that an elevated night-time heart rate may confere an additional risk on top of office RHR.

Effect of Evening Bromazepam Administration on Blood Pressure and Heart Rate in Mild Hypertensive Patients

Pharmacology ◽  
2019 ◽  
Vol 104 (1-2) ◽  
pp. 1-6
Author(s):  
Alfredo Costa ◽  
Daniele Bosone ◽  
Matteo Cotta Ramusino ◽  
Giulia Perini ◽  
Natascia Ghiotto ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Ambulatory Monitoring ◽  
Night Time ◽  
Double Blind ◽  
Hypertensive Patients ◽  
Treatment Groups ◽  
Significant Difference ◽  
Nocturnal Increase ◽  
Mild Hypertensive

Aim: To assess the effects of chronic evening oral administration of bromazepam alone or in combination with propranolol on ambulatory blood pressure (BP) and heart rate (HR) in mild hypertensive subjects. Methods: Thirty-seven mild hypertensive patients after a 2-week placebo period were randomized to bromazepam 3 mg, propranolol 40 mg, bromazepam 3 mg plus propranolol 40 mg or placebo for 2 weeks according to a double-blind, double dummy, cross-over design. After each treatment period, 24-h BP and HR ambulatory monitoring was performed by using a non-invasive device. Results: Ambulatory monitoring showed that during night-time SBP and DBP values were unaffected by bromazepam as compared to placebo, whereas SBP was significantly reduced by propranolol both when taken alone and in combination with bromazepam. HR nocturnal values were significantly reduced by propranolol, whereas they were significantly increased by bromazepan both when taken alone (+11.5%, p < 0.05 vs. placebo) and in combination with propranolol (+12.8%, p < 0.05 vs. propranolol). No significant difference in day-time values of SBP, DBP and HR was observed among the 4 treatment groups. Conclusions: In mild hypertensive patients, evening consumption of bromazepam for a 2-week period did not affect BP, while it increased nocturnal HR. Such an increase was observed both when bromazepam was taken alone and in combination with propranolol, which suggests that it depends on a bromazepam mediated decrease in vagal tone. Whatever the mechanism, the HR nocturnal increase might be of clinical relevance, due to the role of high HR as cardiovascular risk factor, particularly in already at risk hypertensive subjects.

Low Resting Heart Rate and Antisocial Behavior

2009 ◽  
Vol 36 (11) ◽  
pp. 1125-1140 ◽  
Author(s):  
Todd A. Armstrong ◽  
Shawn Keller ◽  
Travis W. Franklin ◽  
Scott N. Macmillan
Keyword(s):  
Heart Rate ◽  
Antisocial Behavior ◽  
Multivariate Regression ◽  
Regression Models ◽  
Large Body ◽  
Self Control ◽  
Resting Heart Rate ◽  
Peer Delinquency ◽  
Criminological Theories ◽  
The Relationship

Despite a large body of research demonstrating a clear and consistent relationship between resting heart rate and antisocial behavior, little is understood about the relative influence on antisocial behavior of resting heart rate and other constructs central to criminological theories. Here, the authors offer an initial effort to bridge this gap in the literature by testing the relationship between resting heart rate and a measure of antisocial behavior net of attachment to parents, self-control, peer delinquency, and potential physiological confounds. Results from ANOVA show that those with low resting heart rates have significantly higher rates of severe antisocial behavior and aggressive antisocial behavior net of physiological confounds. Results from multivariate regression models show that low resting heart rate has a statistically significant relationship with severe antisocial behavior and aggressive behavior in models controlling for attachment to parents, self-control, peer delinquency, and physiological confounds.

scholarly journals Resting Heart Rate Pattern During Follow-Up and Mortality in Hypertensive Patients

Hypertension ◽  
2010 ◽  
Vol 55 (2) ◽  
pp. 567-574 ◽  
Author(s):  
Laura Paul ◽  
Claire E. Hastie ◽  
Weiling S. Li ◽  
Craig Harrow ◽  
Scott Muir ◽  
...  
Keyword(s):  
Heart Rate ◽  
Resting Heart Rate ◽  
Hypertensive Patients ◽  
Heart Rate Pattern

Night-time heart rate cut-off point definition by resting office tachycardia in untreated hypertensive patients

2014 ◽  
Vol 32 (5) ◽  
pp. 1016-1024 ◽  
Author(s):  
Ernest Vinyoles ◽  
Alejandro de la Sierra ◽  
Albert Roso ◽  
Juan J. de la Cruz ◽  
Manuel Gorostidi ◽  
...  
Keyword(s):  
Heart Rate ◽  
Night Time ◽  
Hypertensive Patients

scholarly journals The Impact of Resting Heart Rate and Hypertension on the Prevalence of Stroke in Sudanese Adults: A Population- Based Cross Sectional Study

2021 ◽  
pp. 165-175
Author(s):  
D. A. Hassan ◽  
M. I. Elamin ◽  
M. Elamin ◽  
H. M. Beheiry ◽  
A. A. Abdalla ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
Resting Heart Rate ◽  
Sectional Study ◽  
Cross Sectional ◽  
Hypertensive Patients ◽  
Increased Risk ◽  
The Impact

Aims: To investigate the effect of elevated resting heart rate (RHR), hypertension (HTN) and associated risk factors on the prevalence of stroke among Sudanese adults.  Study Design: This is a cross-sectional study based on a survey conducted by Sudanese society of hypertension during the May Month of Measurement (MMM), 2018 campaign. Methods: A total of 12281 respondents (mean age: 32.5±14.5 years, 49% men) were included. Structured questionnaires of demographic data, and self-reported medical history were filled by all respondents and analyzed.  Blood pressure and RHR were measured using an Omron BP monitor. Participants were divided into two main cohorts: normotensive (n=9497, 77.3%) and hypertensive (n=2784, 22.7%) participants. Each cohort was then segregated into three sub-cohorts using RHR tertiles (T1: <79 bpm; T2: RHR: 79 to 100 bpm; and T3:>100 bpm). Results: Multivariate logistic regression analyses were performed to assess the individual and combined effect of RHR and HTN on prevalence of stroke. Hypertensive patients were more likely to develop stroke compared to normotensive participants (OR= 2. 968, 95% CI 2.028-4.345). Within the hypertensive cohort, RHR T3 participants had a significantly increased risk of stroke compared to RHR T1-T2 combined (OR= 2.35, 95% CI1.043-5.323). Individuals of RHR T3 sub-cohort were more likely to be younger, leaner and displayed significantly higher level of both systolic & diastolic blood pressure compared to RHR T1 and T2 groups. Diabetes Mellitus and smoking increased the odds of stroke among both normotensives (OR (95% CI):5.6 (2.24- 14.09), 3.17 (1.71-6.08 respectively), and hypertensives (OR (95% CI): 4.40 (2.26-8.58), 2.03 (0.95-4.32) respectively). Female gender and older age also increases the odds of stroke among hypertensives (OR (95% CI): 1.85 (1.00- 3.45) and 2.00 (1.02- 4.17) respectively.   In conclusion, this study demonstrated that HTN was an independent risk factor of stroke. The effect of elevated RHR on stroke was only prominent when joined to high blood pressure. Prevalence of tachycardia was higher among the young participants which make them more prone to stroke if the condition is associated with HTN. Our results highlight the importance of addressing elevated RHR to reduce the risk of stroke particularly among hypertensive patients.  

Regional Frontal Lobe Response Magnitudes During Affective Shifting Covary With Resting Heart Rate Variability in Healthy Volunteers

2016 ◽  
Vol 30 (4) ◽  
pp. 165-174 ◽  
Author(s):  
Ryan Smith ◽  
John J.B. Allen ◽  
Julian F. Thayer ◽  
Richard D. Lane
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Healthy Subjects ◽  
Emotional Reactivity ◽  
Bold Signal ◽  
Resting Heart Rate ◽  
Functional Magnetic Resonance ◽  
Absolute Value ◽  
Cardiac Vagal Control ◽  
Resting Heart Rate Variability

Abstract. We hypothesized that in healthy subjects differences in resting heart rate variability (rHRV) would be associated with differences in emotional reactivity within the medial visceromotor network (MVN). We also probed whether this MVN-rHRV relationship was diminished in depression. Eleven healthy adults and nine depressed subjects performed the emotional counting stroop task in alternating blocks of emotion and neutral words during functional magnetic resonance imaging (fMRI). The correlation between rHRV outside the scanner and BOLD signal reactivity (absolute value of change between adjacent blocks in the BOLD signal) was examined in specific MVN regions. Significant negative correlations were observed between rHRV and average BOLD shift magnitude (BSM) in several MVN regions in healthy subjects but not depressed subjects. This preliminary report provides novel evidence relating emotional reactivity in MVN regions to rHRV. It also provides preliminary suggestive evidence that depression may involve reduced interaction between the MVN and cardiac vagal control.

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