scholarly journals Synthesis, Characterization and in Vitro Anticancer Activity of DOX-Loaded Copper Oxide Nanoparticles Targeting Breast Cancer

2013 ◽  
Vol 24 ◽  
pp. iii19
Author(s):  
V. Nipun Babu ◽  
R. Thangam ◽  
S. Kannan ◽  
P. Gunasekaran
Keyword(s):  
Breast Cancer ◽  
Copper Oxide ◽  
Anticancer Activity ◽  
Copper Oxide Nanoparticles ◽  
Oxide Nanoparticles

Folic acid modified copper oxide nanoparticles for targeted delivery in in vitro and in vivo systems

RSC Advances ◽  
2015 ◽  
Vol 5 (83) ◽  
pp. 68169-68178 ◽  
Author(s):  
Dipranjan Laha ◽  
Arindam Pramanik ◽  
Sourav Chattopadhyay ◽  
Sandip kumar Dash ◽  
Somenath Roy ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Folic Acid ◽  
Cancer Therapy ◽  
Copper Oxide ◽  
Targeted Delivery ◽  
Copper Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Breast Cancer Therapy

Targeted delivery of copper oxide nanoparticles for breast cancer therapy.

scholarly journals Synthesis and Characterization of Copper Oxide Nanoparticles from Aqueous Extract of Cyanotis tuberosa (Roxb.) Schult. & Schult. F. and Analysis of Antioxidant, Antimicrobial and Anticancer Activity

2021 ◽  
pp. 138-153
Author(s):  
Gorantla Ramakrishna ◽  
Mulla Kaja Peer ◽  
Kavitha Bommana ◽  
Yasodamma Nimmanapalli
Keyword(s):  
Copper Oxide ◽  
Anticancer Activity ◽  
Aqueous Extract ◽  
Human Cancer ◽  
Copper Oxide Nanoparticles ◽  
Klebsiella Pneumonia ◽  
Oxide Nanoparticles ◽  
Face Centered Cubic

Cyanotis tuberosa (Roxb.) Schult. & Schult.f family Commelinaceae is traditionally used as ethnomedicine for curing several health problems in India. In this study copper oxide CuONPs were synthesized using C. tuberosa tubers aqueous extract. The biosynthesized CuONPs were characterized using an Ultra violet–visible spectroscopy, Fourier-Transform Infra Red spectroscopy, X-RAY Diffraction Analysis, Scanning electron microscopy. The results obtained from SEM showed that the copper oxide nanoparticles were a face-centered cubic crystal structure. The characterization of the biosynthesized CuONPs through EDS also indicated that the reaction product was composed of highly pure CuO NPs. The invitro antimicrobial activity of different concentrations of green synthesized copper oxide nanoparticles of C. tuberosa showed that the highest inhibition zone was observed on Klebsiella pneumonia (15.25 mm). Furthermore, the antioxidant activity of green synthesized CuONPs of C. tuberosa tubers aqueous extract was also tested the highest percentage activity was exhibited at 100 μg/ml CuONPs (56.32). The human cancer cell line was used for cytotoxicity analysis at 48 hrs of incubation period, a significant abatement in cell viability was observed against the treated cell lines. The study concludes that the C. tuberosa tubers aqueous extract can be successfully used for the synthesis of CuONPs that exhibit effective in vitro anti-bacterial, antioxidant and anticancer activity.

scholarly journals Synthesis, characterization, anticancer activity assessment and apoptosis signaling of fucoidan mediated copper oxide nanoparticles

2021 ◽  
pp. 103250
Author(s):  
Abdul-Rehman Phull ◽  
Akhtar Ali ◽  
Kyu Ree Dhong ◽  
Muhammad Zia ◽  
Prasad G. Mahajan ◽  
...  
Keyword(s):  
Copper Oxide ◽  
Anticancer Activity ◽  
Copper Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Activity Assessment

scholarly journals In vitro intestinal toxicity of copper oxide nanoparticles in rat and human cell models

2019 ◽  
Vol 13 (6) ◽  
pp. 795-811 ◽  
Author(s):  
Taylor E. Henson ◽  
Jana Navratilova ◽  
Alan H. Tennant ◽  
Karen D. Bradham ◽  
Kim R. Rogers ◽  
...  
Keyword(s):  
Copper Oxide ◽  
Human Cell ◽  
Copper Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Cell Models ◽  
Intestinal Toxicity

Green synthesis of copper oxide nanoparticles using sinapic acid: an underpinning step towards antiangiogenic therapy for breast cancer

2019 ◽  
Vol 24 (5) ◽  
pp. 633-645 ◽  
Author(s):  
Desingh Raj Preeth ◽  
Manickaraj Shairam ◽  
Natarajan Suganya ◽  
Roshandel Hootan ◽  
Ravishankar Kartik ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Copper Oxide ◽  
Green Synthesis ◽  
Antiangiogenic Therapy ◽  
Sinapic Acid ◽  
Copper Oxide Nanoparticles ◽  
Oxide Nanoparticles

Characterization and Anticancer Activities of Green Synthesized CuO Nanoparticles, A Review

2020 ◽  
Vol 20 ◽  
Author(s):  
Seyedeh R. Alizadeh ◽  
Mohammad A. Ebrahimzadeh
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Copper Oxide ◽  
Medical Science ◽  
Copper Oxide Nanoparticles ◽  
Cuo Nanoparticles ◽  
Oxide Nanoparticles ◽  
Anticancer Activities

Background: Cancer is defined as an abnormal/uncontrolled cell growth that shows rapid cell division. This disease is annually recognized in more than ten million people. Nanomaterials can be used as new strategies for cancer therapy. Nanostructured devices have developed for drug delivery and controlled release and created novel anticancer chemotherapies. Nanomaterials were taken into consideration because of their new properties, containing a large specific surface area and high reactivity. Copper oxide nanoparticles (CuONPs) have potential applications in many fields like heterogeneous catalysis, antibacterial, anticancer, antioxidant, antifungal, antiviral, imaging agents, and drug delivery agents in biomedicine. CuONPs display different physical properties, such as hightemperature superconductivity, electron correlation effects, and spin dynamics. NPs can be synthesized using different methods like physical, chemical, and biological methods. Methods: Copper oxide nanoparticles (CuONPs) have been suggested for its broad usage in biomedical applications. In this review, we tried to exhibit the results of significant anticancer activity of green synthesized CuONPs and their characterization by different analytical techniques such as UV-Vis, FT-IR, XRD, EDAX, DLS, SEM, and TEM. Results: The green method for the synthesis of CuO nanoparticles as eco-friendly, cost-effective, and facile method is the more effective method. Synthesized CuONPs from this method have an appropriate size and shape. The Green synthesized CuONPs exhibited high potential against several breast cancer (AMJ-13, MCF-7, and HBL-100 cell lines), cervical cancer (HeLa), colon cancer (HCT-116), gastric cancer (human adenocarcinoma AGS cell line), lung cancer (A549), leukemia cancer, and other cancers with the main toxicity approach of increasing ROS production. Conclusion: The present review confirms the importance of green synthesized CuO nanoparticles in medical science especially cancer therapy that exhibited high activity against different cancer in both in vitro and in vivo. The main toxicity approach of CuONPs is increasing the production of reactive oxygen species (ROS). It needs to perform more studies about in vivo cancer therapy and following clinical trial testing in the future. We believe that green synthesized CuO nanoparticles can be used for the improvement of different diseases.

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